Effect of clarithromycin on airway obstruction and inflammatory markers in induced sputum in cystic fibrosis: A pilot study

2001 ◽  
Vol 32 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Claudia L. Ordoñez ◽  
Michael Stulbarg ◽  
H. Grundland ◽  
Jane T. Liu ◽  
Homer A. Boushey
2007 ◽  
Vol 42 (4) ◽  
pp. 362-369 ◽  
Author(s):  
Tulay Guran ◽  
Refika Ersu ◽  
Bulent Karadag ◽  
Ihsan Nuri Akpinar ◽  
Gulderen Yanikkaya Demirel ◽  
...  

2004 ◽  
Vol 37 (11) ◽  
pp. 1031-1036 ◽  
Author(s):  
Argyrios A. Smountas ◽  
Larry C. Lands ◽  
Shawn R. Mohammed ◽  
Vijaylaxmi Grey

Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 622
Author(s):  
Dominic Weller ◽  
Samantha Franklin ◽  
Peter White ◽  
Glenn Shea ◽  
Kate Fenner ◽  
...  

This article reports on the results of a survey of racehorse trainers (n = 112) outlining the reasons for tongue-tie (TT) and noseband (NB) use by Thoroughbred trainers (TBTs) (n = 72) and Standardbred trainers (SBTs) (n = 40). The study also investigated the reported effectiveness of TTs and possible complications arising from their use. Tongue-tie use was reported by 62.5% (n = 70) of racehorse trainers. The reasons for TT use varied between TBTs and SBTs. For TBTs, the most common reason for TT use was to prevent or reduce airway obstruction (72.3%, n = 34), followed closely by to prevent or reduce airway noise (55.3%, n = 16). Standardbred trainers assigned equal importance for TT use [to prevent or reduce airway obstruction (69.6%, n = 16) and to prevent the horse from moving its tongue over the bit (69.6%, n = 16)]. Tongue-ties were considered significantly less effective at improving performance than at reducing airway obstruction and preventing the tongue from moving over the bit (t = −2.700, p = 0.0007). For respondents who used both TTs and NBs, there was a mild to moderate positive association between the reasons for using TTs and NBs. Of the 70 TT-using respondents, 51.4% (n = 36) recorded having encountered either a physical or behavioural complication due to TT use, with redness/bruising of the tongue (20.0%, n = 14) being the most common physical complication reported. Duration of use influenced the risk of observing complications. The likelihood of a respondent reporting a behavioural complication due to TT use increased with every minute of reported application and a nine-minute increment in application period doubled the odds of a respondent reporting a complication. Tightness was a risk factor for physical complications: Checking TT tightness by noting the tongue as not moving was associated with increased reporting of physical complications (OR = 6.59; CI 1.1–67.5). This pilot study provides some insight into how and why TTs are applied by some racehorse trainers, and the potential risks associated with their use. A further study of a larger cohort is recommended because these results are valid for only the 112 trainers who responded and cannot be generalized to the equine industry.


2012 ◽  
Vol 11 ◽  
pp. S111
Author(s):  
C. O'Connor ◽  
C. Reilly ◽  
S. Kelly ◽  
A. Leeney ◽  
C. O'Farrell ◽  
...  

2021 ◽  
Vol 20 ◽  
pp. S104
Author(s):  
D. Morrissy ◽  
A. Curran ◽  
T. Vagg ◽  
J. Dorgan ◽  
C. Fleming ◽  
...  

2021 ◽  
pp. 28-31
Author(s):  
А.Г. ИСАЕВА ◽  
Л.Ш. КАСЕНОВА ◽  
Л.Д. БЕКЖАНОВА ◽  
А.М. АБДУКАЛЫКОВ ◽  
З.М. АТАШОВА ◽  
...  

Клиническая симптоматика туберкулеза в сочетании с муковисцидозом была обусловлена суммацией проявлений сочетанной патологии и протекала, как тяжелая хроническая пневмония, непрерывно рецидивирующая, с выраженным синдромом обструкции дыхательных путей. Туберкулезное воспаление характеризовалось большей площадью поражения, деструкцией легочной ткани и обнаружением микобактерий туберкулеза в мокроте. Независимо от наличия сопутствующей патологии применялась химиотерапия в стандартном режиме.Цель исследования: оценить течение заболевания и эффективность лечения туберкулезом органов дыхания с учетом наличия сопутствующих заболеваний. Clinical symptoms of tuberculosis in association with cystic fibrosis was determined by summation of the manifestations of comorbidity and proceeded as severe chronic pneumonia, recurrent continuously, with marked airway obstruction syndrome. Tuberculous inflammation was characterized by a larger lesion area, destruction of the lung tissue and the detection of MBT in sputum. Regardless of the presence of concomitant pathology, chemotherapy was used in standard mode.


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