scholarly journals High Loading Efficiency and Controlled Release of Bioactive Immunotherapeutic Proteins Using Vaterite Nanoparticles (Part. Part. Syst. Charact. 7/2021)

2021 ◽  
Vol 38 (7) ◽  
pp. 2170013
Author(s):  
Ghizlane Choukrani ◽  
Jimena Álvarez Freile ◽  
Natasha Ustyanovska Avtenyuk ◽  
Wei Wan ◽  
Kerstin Zimmermann ◽  
...  
Keyword(s):  
Controlled Release ◽  
High Loading ◽  
Loading Efficiency

scholarly journals High Loading Efficiency and Controlled Release of Bioactive Immunotherapeutic Proteins Using Vaterite Nanoparticles

2021 ◽  
pp. 2100012
Author(s):  
Ghizlane Choukrani ◽  
Jimena Álvarez Freile ◽  
Natasha Ustyanovska Avtenyuk ◽  
Wei Wan ◽  
Kerstin Zimmermann ◽  
...  
Keyword(s):  
Controlled Release ◽  
High Loading ◽  
Loading Efficiency

CONTROLLED RELEASE OF IMIDACLOPRID FROM POLY (STYRENE–DIACETONE CRYLAMIDE)-BASED NANOFORMULATION

2012 ◽  
Vol 11 (06) ◽  
pp. 1240036 ◽  
Author(s):  
KUN QIAN ◽  
YANZHEN GUO ◽  
LIN HE
Keyword(s):  
Controlled Release ◽  
Environmental Pollution ◽  
Active Ingredient ◽  
Release Formulation ◽  
Effective Utilization ◽  
Loading Efficiency ◽  
Diffusion Controlled ◽  
Controlled Release Formulations ◽  
Higher Temperature ◽  
Potential Interactions

Imidacloprid is a neonicotinoids insecticide, which is important for the cash crops such as tomato, rape and so on. The conventional formulation does not only increase the loss of pesticide but also leads to environmental pollution. Controlled-release formulations of pesticide are highly desirable not only for attaining the most effective utilization of the pesticide, but also for reducing environmental pollution. Pesticide imidacloprid was incorporated in poly (styrene–diacetone crylamide)-based formulation to obtain controlled release properties, and the imidacloprid nanocontrolled release formulation was characterized by infrared (IR) and field emission scanning electron microscope (FESEM). Factors related to loading efficiency, swelling and release behaviors of the formulation were investigated. It showed that the loading efficiency could reach about 40% (w/w). The values for the diffusion exponent "n" were in the range of 0.31–0.58, which indicated that the release of imidacloprid was diffusion-controlled. The time taken for 50% of the active ingredient to be released into water, T50, was also calculated for the comparison of formulations in different conditions. The results showed that the formulation with higher temperature and more diacetone crylamide had lower value of T50, which means a quicker release of the active ingredient. This study highlighted some pieces of evidence that improved pesticide incorporation and slower release were linked to potential interactions between the pesticide and the polymer.

Lysozyme Release from Lipid-Based Implants

2014 ◽  
Vol 1060 ◽  
pp. 83-86
Author(s):  
Joana Portugal Mota ◽  
Alexandre Campos ◽  
Duangratana Shuwisitkul ◽  
Nuno Saraiva ◽  
Marisa Nicolai
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Smooth Surface ◽  
Surface Protein ◽  
Protein Release ◽  
Protein Loading ◽  
Loading Efficiency ◽  
Model Protein ◽  
Preparation Techniques ◽  
Potential Use

To better understand lipid-based implants applied to proteins, lysozyme was used as a model protein and was loaded into lipid-based implants in different contents. Cylindrical and spherical implants loaded with lysozyme presented a smooth surface. Protein loading efficiency decreased with increasing lysozyme loading. Lysozyme kept its activity after different implant preparation techniques. Drug release tremendously increased by increasing protein loading from 8.9 to 13.7% (w/w), for cylindrical implants. Lysozyme release was faster from cylindrical implants when compared with the spherical ones. Furthermore, by increasing the hydrophobicity of the lipid, protein release decreased. This study demonstrates the potential use of lipid-based implants for the controlled release of proteins.

Recent research and development of local anesthetic-loaded microspheres

2020 ◽  
Vol 8 (30) ◽  
pp. 6322-6332
Author(s):  
Yi Wei ◽  
Youbin Wu ◽  
Kang Wen ◽  
Nardana Bazybek ◽  
Guanghui Ma
Keyword(s):  
Research And Development ◽  
Local Anesthetic ◽  
Release Rate ◽  
Preparation Method ◽  
High Loading ◽  
Loading Efficiency

This review introduces the recent research and development in local anesthetic-loaded microsphere, as efficient microspheres formulation, the efficient microspheres: optimum preparation method, high loading efficiency, and ideal release rate.

Development of a Chlorantraniliprole Microcapsule Formulation with a High Loading Content and Controlled-Release Property

2017 ◽  
Vol 66 (26) ◽  
pp. 6561-6568 ◽  
Author(s):  
Baoxia Liu ◽  
Yan Wang ◽  
Fei Yang ◽  
Haixin Cui ◽  
Decheng Wu
Keyword(s):  
Controlled Release ◽  
High Loading ◽  
Release Property
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