scholarly journals Characterization of Micro‐ and Nanoscale LuPO 4 :Pr 3+ ,Nd 3+ with Strong UV‐C Emission to Reduce X‐Ray Doses in Radiation Therapy

2019 ◽  
Vol 36 (10) ◽  
pp. 1900280 ◽  
Author(s):  
Sara Espinoza ◽  
Matthias Müller ◽  
Heike Jenneboer ◽  
Lukas Peulen ◽  
Tiara Bradley ◽  
...  
Keyword(s):  
X Ray ◽  
2019 ◽  
Vol 46 (3) ◽  
pp. 1355-1370 ◽  
Author(s):  
Bin Cai ◽  
Eric Laugeman ◽  
Thomas R. Mazur ◽  
Justin C. Park ◽  
Lauren E. Henke ◽  
...  

2021 ◽  
Vol 28 (2) ◽  
pp. 392-403
Author(s):  
P. Pellicioli ◽  
M. Donzelli ◽  
J. A. Davis ◽  
F. Estève ◽  
R. Hugtenburg ◽  
...  

Microbeam radiation therapy (MRT) is a developing radiotherapy, based on the use of beams only a few tens of micrometres wide, generated by synchrotron X-ray sources. The spatial fractionation of the homogeneous beam into an array of microbeams is possible using a multislit collimator (MSC), i.e. a machined metal block with regular apertures. Dosimetry in MRT is challenging and previous works still show differences between calculated and experimental dose profiles of 10–30%, which are not acceptable for a clinical implementation of treatment. The interaction of the X-rays with the MSC may contribute to the observed discrepancies; the present study therefore investigates the dose contribution due to radiation interaction with the MSC inner walls and radiation leakage of the MSC. Dose distributions inside a water-equivalent phantom were evaluated for different field sizes and three typical spectra used for MRT studies at the European Synchrotron Biomedical beamline ID17. Film dosimetry was utilized to determine the contribution of radiation interaction with the MSC inner walls; Monte Carlo simulations were implemented to calculate the radiation leakage contribution. Both factors turned out to be relevant for the dose deposition, especially for small fields. Photons interacting with the MSC walls may bring up to 16% more dose in the valley regions, between the microbeams. Depending on the chosen spectrum, the radiation leakage close to the phantom surface can contribute up to 50% of the valley dose for a 5 mm × 5 mm field. The current study underlines that a detailed characterization of the MSC must be performed systematically and accurate MRT dosimetry protocols must include the contribution of radiation leakage and radiation interaction with the MSC in order to avoid significant errors in the dose evaluation at the micrometric scale.


2014 ◽  
Vol 105 (20) ◽  
pp. 203110 ◽  
Author(s):  
Jeffrey S. Souris ◽  
Shih-Hsun Cheng ◽  
Charles Pelizzari ◽  
Nai-Tzu Chen ◽  
Patrick La Riviere ◽  
...  

2019 ◽  
Vol 52 (22) ◽  
pp. 225601 ◽  
Author(s):  
Salvatore Gallo ◽  
Emanuele Artuso ◽  
Maria Grazia Brambilla ◽  
Grazia Gambarini ◽  
Cristina Lenardi ◽  
...  

Author(s):  
R. E. Herfert

Studies of the nature of a surface, either metallic or nonmetallic, in the past, have been limited to the instrumentation available for these measurements. In the past, optical microscopy, replica transmission electron microscopy, electron or X-ray diffraction and optical or X-ray spectroscopy have provided the means of surface characterization. Actually, some of these techniques are not purely surface; the depth of penetration may be a few thousands of an inch. Within the last five years, instrumentation has been made available which now makes it practical for use to study the outer few 100A of layers and characterize it completely from a chemical, physical, and crystallographic standpoint. The scanning electron microscope (SEM) provides a means of viewing the surface of a material in situ to magnifications as high as 250,000X.


Sign in / Sign up

Export Citation Format

Share Document