Neuroticism, cancer mortality salience, and physician avoidance in cancer survivors: Proximity of treatment matters

2021 ◽  
Author(s):  
Patrick Boyd ◽  
Ashley B. Murray ◽  
Travis Hyams ◽  
Alix G. Sleight ◽  
Richard P. Moser ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Cancer Mortality ◽  
Mortality Salience

Mammography Surveillance and Mortality in Older Breast Cancer Survivors

2007 ◽  
Vol 25 (21) ◽  
pp. 3001-3006 ◽  
Author(s):  
Timothy L. Lash ◽  
Matthew P. Fox ◽  
Diana S.M. Buist ◽  
Feifei Wei ◽  
Terry S. Field ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Survivors ◽  
Cancer Mortality ◽  
Breast Cancer Survivors ◽  
Care Delivery ◽  
Breast Cancer Mortality ◽  
The United States ◽  
Stage I ◽  
Early Stage Disease

Purpose There are more than 2,000,000 breast cancer survivors in the United States today. While surveillance for asymptomatic recurrence and second primary is included in consensus recommendations, the effectiveness of this surveillance has not been well characterized. Our purpose is to estimate the effectiveness of surveillance mammography in a cohort of breast cancer survivors with complete ascertainment of surveillance mammograms and negligible losses to follow-up. Patients and Methods We enrolled 1,846 stage I and II breast cancer patients who were at least 65 years old at six integrated health care delivery systems. We used medical record review and existing databases to ascertain patient, tumor, and therapy characteristics, as well as receipt of surveillance mammograms. We linked personal identifiers to the National Death Index to ascertain date and cause of death. We matched four controls to each breast cancer decedent to estimate the association between receipt of surveillance mammogram and breast cancer mortality. Results One hundred seventy-eight women died of breast cancer during 5 years of follow-up. Each additional surveillance mammogram was associated with a 0.69-fold decrease in the odds of breast cancer mortality (95% CI, 0.52 to 0.92). The protective association was strongest among women with stage I disease, those who received mastectomy, and those in the oldest age group. Conclusion Given existing recommendations for post-therapy surveillance, trials to compare surveillance with no surveillance are unlikely. This large observational study provides support for the recommendations, suggesting that receipt of surveillance mammograms reduces the rate of breast cancer mortality in older patients diagnosed with early-stage disease.

Marital status and suicide as a competing cause of mortality among cancer survivors.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e19113-e19113
Author(s):  
Nosayaba Osazuwa-Peters ◽  
Matthew C Simpson ◽  
Eric Y Du ◽  
Scott A Hong ◽  
Aleksandr R Bukatko ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Marital Status ◽  
Head And Neck ◽  
Cancer Patients ◽  
Cancer Mortality ◽  
The United States ◽  
Mortality Rates ◽  
Suicide Mortality ◽  
Cancer Site ◽  
Mortality Risks

e19113 Background: The risk of suicide among cancer survivors more than double that of the general population, highlighting the need to mitigating risk factors for suicide. While several studies have described marital status, a surrogate for social support, as associated with cancer mortality, it is inconclusive whether marital status impacts suicide as a competing cause of cancer mortality. We tested this hypothesis by describing the association of marital status and suicide among survivors of four cancer sites with the highest suicide mortality rates in the United States. Methods: Adult cancer patients were identified from the Surveillance, Epidemiology and End Results database from 2004 to 2016 for four index cancer sites previously identified with highest suicide mortality rates: pancreas, head and neck, lung/bronchus and stomach ( n = 800,798). Cumulative incidence curves stratified by marital status (divorced/separated, widowed, never unmarried, and married/partnered) estimated unadjusted probability of suicide (outcome of interest). A multivariable competing risk proportional hazards model yielded sub-distribution hazard ratios (sdHRs) and 95% confidence intervals (CI) to estimate the association of marital status with suicide for each cancer site, while controlling for clinical and nonclinical factors. Results: Half (50.7%) of the cohort were married/partnered, males (56.8%), and non-Hispanic whites (71.0%). Mean age at diagnosis was 67.3 years. Most patients (60.9%) had cancer in the lung/bronchus, 17.9% head and neck, 13.8% pancreas, and 8.3% stomach. Unadjusted probability of suicide was highest among head and neck cancer survivors (0.3%). In the fully adjusted model, mortality by suicide was more likely among divorced/separated patients vs. married/partnered patients across cancer sites (sdHRhead and neck = 1.81; 95% CI 1.38, 2.37; sdHRlung/bronchus = 1.68; 95% CI 1.28, 2.19; sdHRpancreas = 2.19; 95% CI 1.27, 3.78; and sdHRstomach = 2.38; 95% CI 1.17, 4.58). Additionally, for lung/bronchus cancer, patients who were never married patients were more likely to die by suicide than those married/partnered (sdHRlung/bronchus = 1.47; 95% CI 1.09, 1.98). Conclusions: Marital status is associated with suicide mortality among cancer survivors, and divorced/separated survivors may have greater suicide mortality risks, independent of cancer site. As overall probability of suicide remains low, these findings might help identify cancer survivors who may be candidates for ongoing surveillance and psychosocial support to mitigate suicide mortality risks.

scholarly journals Long-term non-cancer mortality in pediatric and young adult cancer survivors in Finland

2011 ◽  
Vol 58 (3) ◽  
pp. 421-427 ◽  
Author(s):  
Pinki K. Prasad ◽  
Lisa B. Signorello ◽  
Debra L. Friedman ◽  
John D. Boice ◽  
Eero Pukkala
Keyword(s):  
Young Adult ◽  
Cancer Survivors ◽  
Cancer Mortality ◽  
Young Adult Cancer Survivors ◽  
Adult Cancer Survivors ◽  
Young Adult Cancer

scholarly journals The Impact of Plant-Based Dietary Patterns on Cancer-Related Outcomes: A Rapid Review and Meta-Analysis

Nutrients ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 2010 ◽  
Author(s):  
Esther Molina-Montes ◽  
Elena Salamanca-Fernández ◽  
Belén Garcia-Villanova ◽  
Maria José Sánchez
Keyword(s):  
Prognostic Factors ◽  
Cancer Survivors ◽  
Mediterranean Diet ◽  
Dietary Patterns ◽  
Cancer Mortality ◽  
Meta Analysis ◽  
Vegetarian Diet ◽  
Rapid Review ◽  
Cancer Outcomes ◽  
The Impact

Long-term cancer survivors represent a sizeable portion of the population. Plant-based foods may enhance the prevention of cancer-related outcomes in these patients. We aimed to synthesize the current evidence regarding the impact of plant-based dietary patterns (PBDPs) on cancer-related outcomes in the general population and in cancer survivors. Considered outcomes included overall cancer mortality, cancer-specific mortality, and cancer recurrence. A rapid review was conducted, whereby 2234 original articles related to the topic were identified via Pubmed/Medline. We selected 26 articles, which were classified into studies on PBDPs and cancer outcomes at pre-diagnosis: vegan/vegetarian diet (N = 5), provegetarian diet (N = 2), Mediterranean diet (N = 13), and studies considering the same at post-diagnosis (N = 6). Pooled estimates of the associations between the aforementioned PBDPs and the different cancer outcomes were obtained by applying random effects meta-analysis. The few studies available on the vegetarian diet failed to support its prevention potential against overall cancer mortality when compared with a non-vegetarian diet (e.g., pooled hazard ratio (HR) = 0.97; 95% confidence interval (CI): 0.88–1.06). The insufficient number of studies evaluating provegetarian index scores in relation to cancer mortality did not permit a comprehensive assessment of this association. The association between adherence to the Mediterranean diet and cancer mortality reached statistical significance (e.g., pooled HR = 0.84; 95% CI: 0.79–0.89). However, no study considered the influence of prognostic factors on the associations. In contrast, post-diagnostic studies accounted for prognostic factors when assessing the chemoprevention potential of PBDPs, but also were inconclusive due to the limited number of studies on well-defined plant-based diets. Thus, whether plant-based diets before or after a cancer diagnosis prevent negative cancer-related outcomes needs to be researched further, in order to define dietary guidelines for cancer survivors.

Racial disparities in breast cancer mortality among women with diabetes mellitus.

2017 ◽  
Vol 35 (5_suppl) ◽  
pp. 116-116 ◽  
Author(s):  
Nana Gegechkori ◽  
Pamela Pak ◽  
Juan P. Wisnivesky ◽  
Jenny J Lin
Keyword(s):  
Breast Cancer ◽  
Cancer Survivors ◽  
Cancer Treatment ◽  
Racial Disparities ◽  
Cancer Mortality ◽  
Breast Cancer Survivors ◽  
Cancer Survival ◽  
Breast Cancer Mortality ◽  
Breast Cancer Survival ◽  
Minority Women

116 Background: Multiple reasons have been cited for racial disparities in breast cancer survival, including differences in screening, tumor biology, estrogen receptor status, stage at presentation, treatment and comorbidities. Recent studies suggest that minority women are more likely to have diabetes and diabetes has been shown to increase breast cancer risk and worsen cancer prognosis. We sought to evaluate whether there is disparity in breast cancer mortality among breast cancer survivors with comorbid diabetes. Methods: We identified women >65 years diagnosed with primary breast cancer between 2007 and 2010 from the SEER-Medicare database and followed them for 36 months after cancer diagnoses. Our primary outcome was breast cancer mortality. We excluded patients for whom diagnoses were obtained from death certificates or at autopsy, with incomplete data with regards to the stage at diagnosis and those without Part B coverage. The association between race and breast cancer mortality was assessed using a multivariable Cox regression with competing risk analysis. Results: A total of 9,545 breast cancer survivors with pre-existing diabetes were included in the analysis. Black women were more likely to be diagnosed at later stage and to be younger (p<0.001). There were no differences in cancer treatment by race. After a median follow-up of 36 months, 68.9% of black vs. 73.9% of white patients were still alive (p< .0001). After censoring women who died from other causes and adjusting for age, year of diagnosis, stage, cancer treatment (surgery, chemotherapy and/or radiation) and Charlson comorbidity score, black race remained associated with increased breast cancer mortality (Hazard Ratio 1.45 (95% CI, 1.20-1.73). Conclusions: Even after controlling for cancer-related treatment factors, black breast cancer survivors with diabetes have significantly worse breast cancer survival. Further research should investigate how to improve care for minority women who are at higher risk for breast cancer mortality.

535: Population-Based Case-Control Study of PSA and DRE Screening on Prostate Cancer Mortality

2005 ◽  
Vol 173 (4S) ◽  
pp. 146-146
Author(s):  
Eric J. Bergstralh ◽  
Rosebud O. Roberts ◽  
Michael M. Lieber ◽  
Sara A. Farmer ◽  
Jeffrey M. Slezak ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Mortality ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Prostate Cancer Mortality ◽  
Control Study
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