scholarly journals Validation of the Freund Clock Drawing Test as a screening tool to detect cognitive dysfunction in elderly cancer patients undergoing comprehensive geriatric assessment

2014 ◽  
Vol 23 (10) ◽  
pp. 1172-1177 ◽  
Author(s):  
Michelle Lycke ◽  
Lore Ketelaars ◽  
Tom Boterberg ◽  
Lies Pottel ◽  
Hans Pottel ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Cognitive Dysfunction ◽  
Geriatric Assessment ◽  
Comprehensive Geriatric Assessment ◽  
Screening Tool ◽  
Elderly Cancer Patients ◽  
Clock Drawing Test ◽  
Clock Drawing ◽  
Drawing Test

scholarly journals Relationship between comprehensive geriatric assessment and amyloid PET in older persons with MCI

2020 ◽  
Author(s):  
Fulvio Lauretani ◽  
Livia Ruffini ◽  
Maura Scarlattei ◽  
Marcello Maggio
Keyword(s):  
Cognitive Impairment ◽  
Physical Performance ◽  
Geriatric Assessment ◽  
Comprehensive Geriatric Assessment ◽  
Older Persons ◽  
Amyloid Deposition ◽  
Amyloid Pet ◽  
Clock Drawing Test ◽  
Clock Drawing ◽  
Drawing Test

Abstract Background. The association between amyloid deposition and cognitive, behavioral and physical performance in mild cognitive impairment (MCI) due to Alzheimer's disease (AD) has been poorly investigated, especially in older persons. Methods. We studied the in vivo correlation between the amyloid deposition at Positron Emission Tomography (amyloid-PET) and the presence of memory loss, reduced executive function, physical performance and neuropsychiatric symptoms in older persons with MCI due to AD. Amyloid-PET was performed with 18F-flutemetamol and quantitavely analyzed. Results. We evaluated 48 subjects, including 21 men and 27 women older than 65 years old. We performed in each patient a comprehensive geriatric assessment including MMSE, Clock Drawing Test, ADL, IADL, NPI, SPPB and Hand Grip strength. Then, each patient underwent amyloid-PET. The mean scores obtained at the MMSE by the subjects under examination was 24.97 ± 3.90 with a median NPI of 4. PET scan revealed brain amyloid deposition in 21 persons. Participants with positive amyloid scans exhibited a higher prevalence of pathological clock drawing test (p=0.0009). We did not find a significant association between MMSE score and beta amyloid plaque burden. When amyloid deposition was present, we observed that the deposition was diffuse, involving cortex in a widespread manner, as showed by alterations of CDT. Conclusion. Our findings support the recent hypothesis that amyloid deposition could be associated with multiple cerebral dysfunction, such as executive dysfunction and other cognitive impairment.

Comprehensive Geriatric Assessment Adds Information to Eastern Cooperative Oncology Group Performance Status in Elderly Cancer Patients: An Italian Group for Geriatric Oncology Study

2002 ◽  
Vol 20 (2) ◽  
pp. 494-502 ◽  
Author(s):  
Lazzaro Repetto ◽  
Lucia Fratino ◽  
Riccardo A. Audisio ◽  
Antonella Venturino ◽  
Walter Gianni ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Geriatric Assessment ◽  
Comprehensive Geriatric Assessment ◽  
Daily Living ◽  
Group Performance ◽  
Performance Status ◽  
Eastern Cooperative Oncology Group ◽  
Geriatric Oncology ◽  
Oncology Group ◽  
Elderly Cancer Patients

PURPOSE: To appraise the performance of Comprehensive Geriatric Assessment (CGA) in elderly cancer patients (≥ 65 years) and to evaluate whether it could add further information with respect to the Eastern Cooperative Oncology Group performance status (PS). PATIENTS AND METHODS: We studied 363 elderly cancer patients (195 males, 168 females; median age, 72 years) with solid (n = 271) or hematologic (n = 92) tumors. In addition to PS, their physical function was assessed by means of the activity of daily living (ADL) and instrumental activities of daily living (IADL) scales. Comorbidities were categorized according to Satariano’s index. The association between PS, comorbidity, and the items of the CGA was assessed by means of logistic regression analysis. RESULTS: These 363 elderly cancer patients had a good functional and mental status: 74% had a good PS (ie, lower than 2), 86% were ADL-independent, and 52% were IADL-independent. Forty-one percent of patients had one or more comorbid conditions. Of the patients with a good PS, 13.0% had two or more comorbidities; 9.3% and 37.7% had ADL or IADL limitations, respectively. By multivariate analysis, elderly cancer patients who were ADL-dependent or IADL-dependent had a nearly two-fold higher probability of having an elevated Satariano’s index than independent patients. A strong association emerged between PS and CGA, with a nearly five-fold increased probability of having a poor PS (ie, ≥ 2) recorded in patients dependent for ADL or IADL. CONCLUSION: The CGA adds substantial information on the functional assessment of elderly cancer patients, including patients with a good PS. The role of PS as unique marker of functional status needs to be reappraised among elderly cancer patients.

Comprehensive geriatric assessment test in elderly cancer patients

2015 ◽  
Vol 10 (4) ◽  
pp. 129
Author(s):  
Mohsen Arabi ◽  
AliShahriari Ahmadi ◽  
RoshanakHasheminasb Zavarreh ◽  
Masood Vakili ◽  
Samira Kaffan ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Geriatric Assessment ◽  
Comprehensive Geriatric Assessment ◽  
Elderly Cancer Patients

A novel digital clock drawing test as a screening tool for perioperative neurocognitive disorders: A feasibility study

2020 ◽  
Author(s):  
Richard A. Buckley ◽  
Kelly J. Atkins ◽  
Erika Fortunato ◽  
Brendan Silbert ◽  
David A. Scott ◽  
...  
Keyword(s):  
Feasibility Study ◽  
Screening Tool ◽  
Neurocognitive Disorders ◽  
Clock Drawing Test ◽  
Digital Clock ◽  
Clock Drawing ◽  
Drawing Test
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