scholarly journals Factors associated with attrition from a randomized controlled trial of meaning-centered group psychotherapy for patients with advanced cancer

2011 ◽  
Vol 21 (11) ◽  
pp. 1195-1204 ◽  
Author(s):  
Allison J. Applebaum ◽  
Wendy G. Lichtenthal ◽  
Hayley A. Pessin ◽  
Julia N. Radomski ◽  
N. Simay Gökbayrak ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Group Psychotherapy ◽  
Advanced Cancer ◽  
Controlled Trial ◽  
Factors Associated ◽  
Randomized Controlled

scholarly journals Meaning-centered group psychotherapy for patients with advanced cancer: a pilot randomized controlled trial

2010 ◽  
Vol 19 (1) ◽  
pp. 21-28 ◽  
Author(s):  
William Breitbart ◽  
Barry Rosenfeld ◽  
Christopher Gibson ◽  
Hayley Pessin ◽  
Shannon Poppito ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Group Psychotherapy ◽  
Advanced Cancer ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Pilot Randomized Controlled Trial

scholarly journals Factors Associated With Dropout of Participants in an App-Based Child Injury Prevention Study: Secondary Data Analysis of a Cluster Randomized Controlled Trial

10.2196/21636 ◽  
2021 ◽  
Vol 23 (1) ◽  
pp. e21636
Author(s):  
Jie Li ◽  
Peishan Ning ◽  
Peixia Cheng ◽  
David C Schwebel ◽  
Yang Yang ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Intervention Group ◽  
Demographic Characteristics ◽  
Parenting Education ◽  
Control Group ◽  
Child Injury ◽  
Factors Associated ◽  
Randomized Controlled ◽  
Study Participants

Background Mobile health (mHealth) interventions offer great potential to reach large populations and improve public health. However, high attrition rates threaten evaluation and implementation of mHealth intervention studies. Objective We explored factors associated with attrition of study participants in an mHealth randomized controlled trial (RCT) evaluating an intervention to reduce unintentional child injury risk in China. Methods The cluster RCT compared two groups of an app-based intervention for caregivers of 3-6–year-old children (Bao Hu San). The intervention group received unintentional child injury and parenting education, whereas only parenting education was implemented in the control group. The trial included 2920 study participants in Changsha, China, and lasted 6 months. Data on participant engagement (using the app) were collected electronically throughout the 6-month period. Associations between participant attrition and demographic characteristics, and between attrition and intervention engagement were tested and quantified separately for the intervention and control groups using the adjusted odds ratio (aOR) based on generalized linear mixed models. Results In total, 2920 caregivers from 20 eligible preschools participated, with 1510 in the intervention group and 1410 in the control group. The 6-month attrition rate differed significantly between the two groups (P<.001), at 28.9% (437/1510) in the intervention group and 35.7% (503/1410) in the control group. For the intervention group, the only significant predictor of attrition risk was participants who learned fewer knowledge segments (aOR 2.69, 95% CI 1.19-6.09). For the control group, significant predictors of attrition risk were lower monthly login frequency (aOR 1.48, 95% CI 1.00-2.18), learning fewer knowledge segments (aOR 1.70, 95% CI 1.02-2.81), and shorter learning durations during app engagement (aOR 2.39, 95% CI 1.11-5.15). Demographic characteristics were unrelated to attrition. Conclusions Engagement in the app intervention was associated with participant attrition. Researchers and practitioners should consider how to best engage participants in app-based interventions to reduce attrition. Trial Registration Chinese Clinical Trial Registry ChiCTR-IOR-17010438; http://www.chictr.org.cn/showproj.aspx?proj=17376 International Registered Report Identifier (IRRID) RR2-10.1186/s12889-018-5790-1

Pilot randomized controlled trial of a symptom cluster intervention in advanced cancer

2018 ◽  
Vol 28 (1) ◽  
pp. 76-84 ◽  
Author(s):  
Sharla M. Wells-Di Gregorio ◽  
Donald R. Marks ◽  
Joseph DeCola ◽  
Juan Peng ◽  
Danielle Probst ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Advanced Cancer ◽  
Controlled Trial ◽  
Symptom Cluster ◽  
Randomized Controlled ◽  
Pilot Randomized Controlled Trial

scholarly journals Randomized Controlled Trial of Family Therapy in Advanced Cancer Continued Into Bereavement

2016 ◽  
Vol 34 (16) ◽  
pp. 1921-1927 ◽  
Author(s):  
David W. Kissane ◽  
Talia I. Zaider ◽  
Yuelin Li ◽  
Shira Hichenberg ◽  
Tammy Schuler ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Family Therapy ◽  
Advanced Cancer ◽  
Standard Care ◽  
Controlled Trial ◽  
Significant Treatment ◽  
Prolonged Grief Disorder ◽  
Prolonged Grief ◽  
Randomized Controlled ◽  
High Conflict

Purpose Systematic family-centered cancer care is needed. We conducted a randomized controlled trial of family therapy, delivered to families identified by screening to be at risk from dysfunctional relationships when one of their relatives has advanced cancer. Patients and Methods Eligible patients with advanced cancer and their family members screened above the cut-off on the Family Relationships Index. After screening 1,488 patients or relatives at Memorial Sloan Kettering Cancer Center or three related community hospice programs, 620 patients (42%) were recruited, which represented 170 families. Families were stratified by three levels of family dysfunction (low communicating, low involvement, and high conflict) and randomly assigned to one of three arms: standard care or 6 or 10 sessions of a manualized family intervention. Primary outcomes were the Complicated Grief Inventory-Abbreviated (CGI) and Beck Depression Inventory-II (BDI-II). Generalized estimating equations allowed for clustered data in an intention-to-treat analysis. Results On the CGI, a significant treatment effect (Wald χ2 = 6.88; df = 2; P = .032) and treatment by family-type interaction was found (Wald χ2 = 20.64; df = 4; P < .001), and better outcomes resulted from 10 sessions compared with standard care for low-communicating and high-conflict groups compared with low-involvement families. Low-communicating families improved by 6 months of bereavement. In the standard care arm, 15.5% of the bereaved developed a prolonged grief disorder at 13 months of bereavement compared with 3.3% of those who received 10 sessions of intervention (Wald χ2 = 8.31; df = 2; P =.048). No significant treatment effects were found on the BDI-II. Conclusion Family-focused therapy delivered to high-risk families during palliative care and continued into bereavement reduced the severity of complicated grief and the development of prolonged grief disorder.

Meaning and Purpose (MaP) therapy II: Feasibility and acceptability from a pilot study in advanced cancer

2019 ◽  
Vol 17 (1) ◽  
pp. 21-28 ◽  
Author(s):  
David W. Kissane ◽  
Carrie Lethborg ◽  
Joanne Brooker ◽  
Courtney Hempton ◽  
Sue Burney ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Pilot Study ◽  
Posttraumatic Growth ◽  
Advanced Cancer ◽  
Controlled Trial ◽  
Effect Sizes ◽  
Wait List ◽  
Wait List Control ◽  
Randomized Controlled ◽  
Meaning And Purpose

AbstractObjectiveMeaning and Purpose (MaP) therapy aims to enhance meaning-based coping through a life review that focuses on the value and worth of the person, key relationships, sources of fulfillment, roles, and future priorities in living life out fully. We sought to test the feasibility and acceptability of a six-session model of MaP therapy against a wait-list control cohort in a pilot study seeking effect sizes on measures of adaptation.MethodWe randomized patients with advanced cancer to MaP therapy or wait-list control, with measures administered at baseline and after 6–8 weeks. Wait-list patients could then crossover to receive therapy, with further measures collected postintervention. Adherence to the manualized model was sustained through weekly supervision and fidelity coding of recorded sessions. We used generalized estimating equations to control for baseline and any correlation of data.ResultFrom 134 eligible participants, 57 (43%) consented, and 40 of 45 (89%) offered therapy completed 6 sessions. Key barriers to consenting patients were poor health (15 refusers and 4 withdrawals) and death intervened in 6 participants. MaP therapy generated adequate effect sizes in posttraumatic growth (new possibilities, appreciation of life, and personal strength) and life attitudes (choices and goal seeking) to permit calculation of power for a formal randomized, controlled trial.Significance of resultsDelivery of this model of existentially oriented therapy is feasible and acceptable to patients. A properly powered randomized controlled trial is justified to examine the efficacy of this intervention.

Sign in / Sign up

Export Citation Format

Share Document