Social-cognitive aspects of underserved Latinas preparing to undergo genetic cancer risk assessment for hereditary breast and ovarian cancer

2008 ◽  
Vol 17 (8) ◽  
pp. 774-782 ◽  
Author(s):  
Veronica I. Lagos ◽  
Martin A. Perez ◽  
Charité N. Ricker ◽  
Kathleen R. Blazer ◽  
Nydia M. Santiago ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Risk Assessment ◽  
Cancer Risk ◽  
Social Cognitive ◽  
Cancer Risk Assessment ◽  
Breast And Ovarian Cancer

Genetic cancer risk assessment: A screenshot of the psychosocial profile of women at risk for hereditary breast and ovarian cancer syndrome

2020 ◽  
Vol 29 (4) ◽  
pp. 681-687
Author(s):  
Natalia Campacci ◽  
Henrique Campos Reis Galvão ◽  
Lucas F. Garcia ◽  
Paula C. Ribeiro ◽  
Rebeca S. Grasel ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Risk Assessment ◽  
At Risk ◽  
Cancer Risk ◽  
Cancer Risk Assessment ◽  
Cancer Syndrome ◽  
Breast And Ovarian Cancer ◽  
Psychosocial Profile

Clinical impact of multi-gene panel testing for hereditary breast and ovarian cancer risk assessment.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. 1513-1513
Author(s):  
Leif W. Ellisen ◽  
Allison W. Kurian ◽  
Andrea J Desmond ◽  
Meredith Mills ◽  
Stephen E Lincoln ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Risk Assessment ◽  
Cancer Risk ◽  
Clinical Impact ◽  
Gene Panel ◽  
Cancer Risk Assessment ◽  
Ovarian Cancer Risk ◽  
Breast And Ovarian Cancer ◽  
Panel Testing ◽  
Gene Panel Testing

scholarly journals Hereditary breast and ovarian cancer: risk assessment in minority women and provider knowledge gaps

2016 ◽  
Vol 14 (6) ◽  
pp. 261-267 ◽  
Author(s):  
Nancy Paris ◽  
Sheryl Gabram-Mendola ◽  
Alice Kerber ◽  
Jean O'Connor ◽  
Barbara Crane ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Risk Assessment ◽  
Cancer Risk ◽  
Minority Women ◽  
Cancer Risk Assessment ◽  
Ovarian Cancer Risk ◽  
Breast And Ovarian Cancer ◽  
Knowledge Gaps ◽  
Provider Knowledge

scholarly journals Genetic Testing for Cancer Risk Assessment in Patients With Breast and Ovarian Cancer in Ibadan, Nigeria

2019 ◽  
Vol 5 (Supplement_1) ◽  
pp. 4-4
Author(s):  
Makayla L. Kochheiser ◽  
Toyin I.G. Aniagwu ◽  
Prisca O. Adejumo ◽  
Olufunmilayo I. Olopade
Keyword(s):  
Ovarian Cancer ◽  
Risk Assessment ◽  
Genetic Testing ◽  
Cancer Risk ◽  
Cancer Diagnosis ◽  
Cancer Risk Assessment ◽  
Breast And Ovarian Cancer ◽  
Cancer History ◽  
Family Cancer History ◽  
Ibadan Nigeria

PURPOSE Breast cancer is the leading cause of cancer-related death among women, and ovarian cancer has the highest case fatality rate of all gynecologic cancers. In Nigeria, approximately 80% of breast and ovarian cancer cases are diagnosed at advanced stages. Genetic testing has the potential to reduce the morbidity and mortality associated with late cancer diagnosis. The introduction of genetic testing for cancer risk assessment at University College Hospital (UCH), Ibadan will serve as a model for the rest of Nigeria. The objective of this study was to introduce genetic testing for cancer risk assessment in patients with breast and ovarian cancer in Ibadan, Nigeria and to determine the demographics of women undergoing testing and their perceptions concerning the benefits of and barriers to genetic testing. METHODS Patients with breast or ovarian cancer were recruited at UCH. All patients received genetic counseling and had the opportunity to consent to the Color Genomics Hereditary Cancer Panel Test, free of charge, after due ethical approval. Patients were tested for 30 gene mutations with known associations to eight hereditary cancers. After testing, patients completed a semistandardized questionnaire assessing their sociodemographic information, family cancer history, and perceived benefits and barriers to genetic testing. RESULTS Seven patients with ovarian cancer and 40 patients with breast cancer received genetic counseling, and all chose to undergo subsequent genetic testing. The average age at testing was 49 years, and the average age at cancer diagnosis was 47 years. Eight women reported a known family cancer history, and there were more perceived benefits than barriers to genetic testing. The genetic test results revealed 27 negative mutations, 16 variants of unknown significance, and four pathogenic mutations. CONCLUSION Patients with breast and ovarian cancer at UCH associate genetic testing with benefits for their care. These results suggest potential for growth and sustainability of genetic testing for cancer risk management in Nigeria.

scholarly journals Provider’s Perceptions of Barriers and Facilitators for Latinas to Participate in Genetic Cancer Risk Assessment for Hereditary Breast and Ovarian Cancer

Healthcare ◽  
2018 ◽  
Vol 6 (3) ◽  
pp. 116 ◽  
Author(s):  
Alejandra Hurtado-de-Mendoza ◽  
Kristi Graves ◽  
Sara Gómez-Trillos ◽  
Lyndsay Anderson ◽  
Claudia Campos ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Risk Assessment ◽  
At Risk ◽  
Cancer Risk ◽  
Genetic Counselors ◽  
Barriers And Facilitators ◽  
Cancer Risk Assessment ◽  
Care Providers ◽  
Latina Women ◽  
Breast And Ovarian Cancer

The Comprehensive Cancer Network (NCCN) recommends genetic cancer risk assessment (GCRA) referral to women at high risk of hereditary breast and ovarian cancer. Latinas affected by breast cancer have the second highest prevalence of BRCA1/2 mutations after Ashkenazi Jews. Compared to non-Hispanic Whites, Latinas have lower GCRA uptake. While some studies have identified barriers for GCRA use in this population, few studies have focused on health care providers’ perspectives. The purpose of the study was to examine providers’ perceptions of barriers and facilitators for at-risk Latina women to participate in GCRA and their experiences providing services to this population. We conducted semi-structured interviews with 20 healthcare providers (e.g., genetic counselors, patient navigators) recruited nationally through snowballing. Interviews were transcribed. Two coders independently coded each interview and then met to reconcile the codes using Consensual Qualitative Research guidelines. Providers identified several facilitators for GCRA uptake (e.g., family, treatment/prevention decisions) and barriers (e.g., cost, referrals, awareness, stigma). Genetic counselors described important aspects to consider when working with at-risk Latina including language barriers, obtaining accurate family histories, family communication, and testing relatives who live outside the US. Findings from this study can inform future interventions to enhance uptake and quality of GCRA in at-risk Latina women to reduce disparities.

Sign in / Sign up

Export Citation Format

Share Document