Green solvent approach for printable large deformation thermoplastic elastomer based piezoresistive sensors and their suitability for biomedical applications

2016 ◽  
Vol 54 (20) ◽  
pp. 2092-2103 ◽  
Author(s):  
Bruna F. Gonçalves ◽  
Pedro Costa ◽  
Juliana Oliveira ◽  
Sylvie Ribeiro ◽  
Vitor Correia ◽  
...  
2016 ◽  
Vol 18 (19) ◽  
pp. 5151-5159 ◽  
Author(s):  
DooLi Kim ◽  
Octavio R. Salazar ◽  
Suzana Pereina Nunes

Polysulfone membranes are key tools in biomedical applications, such as hemodialysis and protein separation, in the food industry, and in seawater desalination. Ionic liquids are proposed as green solvent for membrane manufacture with tailored peptide selectivity.


2006 ◽  
Vol 920 ◽  
Author(s):  
Xiaoyin Cheng ◽  
H. Y. J. Tsang ◽  
Y. Li ◽  
M. Y. Leung ◽  
X. M. Tao ◽  
...  

AbstractConductive-polymer coated fabrics have been investigated as intelligent materials in the past years. In this paper, a flexible fabric strain sensor coated with polypyrrole is reported, which is featured with high sensitivity, good stability and large deformation. It is fabricated by chemical vapor deposition at low temperature. The effects of temperature, humidity, acid and alkaline medium have been assessed. The conductivity-strain tests reveal the sensor exhibits a high strain sensitivity of ~160 for a deformation as large as 50%, while its good stability is indicated by a small loss of conductivity after the thermal and humidity aging tests, and supported by the slight change in conductivity and sensitivity over a storage of eighteen months. The acid and alkaline solution mainly decreased their initial conductivity but have the slight effect to their sensitivity. The flexible fabric strain sensor is expected to be a promising “soft” smart material in the smart garment, wearable hardware and biomedical applications.


Seikei-Kakou ◽  
2018 ◽  
Vol 30 (11) ◽  
pp. 594-602
Author(s):  
Yumiko Isogai ◽  
Masanori Wada ◽  
Atsushi Yokoyama ◽  
Masanobu Murata ◽  
Takuya Sumiyama ◽  
...  

ACS Omega ◽  
2018 ◽  
Vol 3 (10) ◽  
pp. 12648-12657 ◽  
Author(s):  
Ayse Turgut ◽  
Mohammad O. Tuhin ◽  
Ozan Toprakci ◽  
Melissa A. Pasquinelli ◽  
Richard J. Spontak ◽  
...  

Author(s):  
T. L. Hayes

Biomedical applications of the scanning electron microscope (SEM) have increased in number quite rapidly over the last several years. Studies have been made of cells, whole mount tissue, sectioned tissue, particles, human chromosomes, microorganisms, dental enamel and skeletal material. Many of the advantages of using this instrument for such investigations come from its ability to produce images that are high in information content. Information about the chemical make-up of the specimen, its electrical properties and its three dimensional architecture all may be represented in such images. Since the biological system is distinctive in its chemistry and often spatially scaled to the resolving power of the SEM, these images are particularly useful in biomedical research.In any form of microscopy there are two parameters that together determine the usefulness of the image. One parameter is the size of the volume being studied or resolving power of the instrument and the other is the amount of information about this volume that is displayed in the image. Both parameters are important in describing the performance of a microscope. The light microscope image, for example, is rich in information content (chemical, spatial, living specimen, etc.) but is very limited in resolving power.


Author(s):  
Philippe Fragu

The identification, localization and quantification of intracellular chemical elements is an area of scientific endeavour which has not ceased to develop over the past 30 years. Secondary Ion Mass Spectrometry (SIMS) microscopy is widely used for elemental localization problems in geochemistry, metallurgy and electronics. Although the first commercial instruments were available in 1968, biological applications have been gradual as investigators have systematically examined the potential source of artefacts inherent in the method and sought to develop strategies for the analysis of soft biological material with a lateral resolution equivalent to that of the light microscope. In 1992, the prospects offered by this technique are even more encouraging as prototypes of new ion probes appear capable of achieving the ultimate goal, namely the quantitative analysis of micron and submicron regions. The purpose of this review is to underline the requirements for biomedical applications of SIMS microscopy.Sample preparation methodology should preserve both the structural and the chemical integrity of the tissue.


Author(s):  
J. D. Shelburne ◽  
Peter Ingram ◽  
Victor L. Roggli ◽  
Ann LeFurgey

At present most medical microprobe analysis is conducted on insoluble particulates such as asbestos fibers in lung tissue. Cryotechniques are not necessary for this type of specimen. Insoluble particulates can be processed conventionally. Nevertheless, it is important to emphasize that conventional processing is unacceptable for specimens in which electrolyte distributions in tissues are sought. It is necessary to flash-freeze in order to preserve the integrity of electrolyte distributions at the subcellular and cellular level. Ideally, biopsies should be flash-frozen in the operating room rather than being frozen several minutes later in a histology laboratory. Electrolytes will move during such a long delay. While flammable cryogens such as propane obviously cannot be used in an operating room, liquid nitrogen-cooled slam-freezing devices or guns may be permitted, and are the best way to achieve an artifact-free, accurate tissue sample which truly reflects the in vivo state. Unfortunately, the importance of cryofixation is often not understood. Investigators bring tissue samples fixed in glutaraldehyde to a microprobe laboratory with a request for microprobe analysis for electrolytes.


Author(s):  
Yasushi P. Kato ◽  
Michael G. Dunn ◽  
Frederick H. Silver ◽  
Arthur J. Wasserman

Collagenous biomaterials have been used for growing cells in vitro as well as for augmentation and replacement of hard and soft tissues. The substratum used for culturing cells is implicated in the modulation of phenotypic cellular expression, cellular orientation and adhesion. Collagen may have a strong influence on these cellular parameters when used as a substrate in vitro. Clinically, collagen has many applications to wound healing including, skin and bone substitution, tendon, ligament, and nerve replacement. In this report we demonstrate two uses of collagen. First as a fiber to support fibroblast growth in vitro, and second as a demineralized bone/collagen sponge for radial bone defect repair in vivo.For the in vitro study, collagen fibers were prepared as described previously. Primary rat tendon fibroblasts (1° RTF) were isolated and cultured for 5 days on 1 X 15 mm sterile cover slips. Six to seven collagen fibers, were glued parallel to each other onto a circular cover slip (D=18mm) and the 1 X 15mm cover slip populated with 1° RTF was placed at the center perpendicular to the collagen fibers. Fibroblast migration from the 1 x 15mm cover slip onto and along the collagen fibers was measured daily using a phase contrast microscope (Olympus CK-2) with a calibrated eyepiece. Migratory rates for fibroblasts were determined from 36 fibers over 4 days.


Sign in / Sign up

Export Citation Format

Share Document