Synthesis and characterization of a series of biodegradable and biocompatible PEG-supported poly(lactic-ran-glycolic acid) amphiphilic barbell-like copolymers

2008 ◽  
Vol 46 (11) ◽  
pp. 3802-3812 ◽  
Author(s):  
De Dai Lu ◽  
Jian Chao Yuan ◽  
Hongguang Li ◽  
Zi-Qiang Lei
Keyword(s):  
Glycolic Acid ◽  
Synthesis And Characterization

scholarly journals Synthesis and Characterization of Erythromycin Loaded PLGA and PCL Microspheres: Antimicrobial Application

2021 ◽  
Author(s):  
Lamia Bennabi ◽  
Ilham Abedelemalek ◽  
Abedelkader Ammari ◽  
Khaldia Sediri ◽  
Fatima Bennabi ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Glycolic Acid ◽  
Release Kinetics ◽  
Synthesis And Characterization ◽  
X Ray Diffraction ◽  
X Ray ◽  
Complementary Effect ◽  
Kinetics Of ◽  
Scanning Electron

Abstract We presents in this work the preparation of several formulations, based on biocompatible biodegradable polymers: polycaprolactone (PCL) and poly(lactic-co-glycolic) acid (PLGA) loaded with Erythromycin (ERYT) antibiotic. These biocompatible materials were used to prepare microspheres with and without immobilized ERYT via simple evaporation method by simple emulsion. The particle size was determined by scanning electron microscopy and the absence of the interaction with ERYT was confirmed via X-ray diffraction and infrared spectroscopy. The release kinetics of ERYT were studied and then, ERYT loaded PCL and PLGA blends microspheres were used for the inhibition of gram-positive S. aureus strain. The microbial activity was carried-out by Agar diffusion disc method. The results show that PCL/PLGA blend and PCL alone inhibited the strain by ERYT present in kinetic aliquots with the complementary effect of the polymers. A numerical model was proposed for modeling the kinetics reported in our study.

scholarly journals Synthesis and characterization of a poly(lactic-co-glycolic acid) core + poly(N-isopropylacrylamide) shell nanoparticle system

Biomatter ◽  
2012 ◽  
Vol 2 (4) ◽  
pp. 195-201 ◽  
Author(s):  
Aaron M. Kosinski ◽  
Jamie L. Brugnano ◽  
Brandon L. Seal ◽  
Frances C. Knight ◽  
Alyssa Panitch
Keyword(s):  
Glycolic Acid ◽  
Synthesis And Characterization ◽  
Nanoparticle System

Synthesis and characterization of poly(lactic acid-co-glycolic acid) complex microspheres as drug carriers

2016 ◽  
Vol 31 (4) ◽  
pp. 544-552 ◽  
Author(s):  
Fang Wang ◽  
Xiuxiu Liu ◽  
Jian Yuan ◽  
Siqian Yang ◽  
Yueqin Li ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Glycolic Acid ◽  
Drug Carriers ◽  
Synthesis And Characterization ◽  
Poly Lactic Acid ◽  
Acid Complex

scholarly journals Synthesis and characterization of magnesium gluconate contained poly(lactic-co-glycolic acid)/chitosan microspheres

2016 ◽  
Vol 203 ◽  
pp. 59-66 ◽  
Author(s):  
Shekh M. Rahman ◽  
Christopher Mahoney ◽  
Jagannathan Sankar ◽  
Kacey G. Marra ◽  
Narayan Bhattarai
Keyword(s):  
Glycolic Acid ◽  
Synthesis And Characterization ◽  
Chitosan Microspheres ◽  
Magnesium Gluconate
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