Temperature-sensitive hydrogel microspheres formed by liquid-liquid phase transitions of aqueous solutions of poly(N,N-dimethylacrylamide-co-allyl methacrylate)

2005 ◽  
Vol 43 (8) ◽  
pp. 1641-1648 ◽  
Author(s):  
Xiangchun Yin ◽  
Harald D. H. Stöver
Keyword(s):  
Phase Transitions ◽  
Liquid Phase ◽  
Aqueous Solutions ◽  
Temperature Sensitive ◽  
Temperature Sensitive Hydrogel ◽  
Allyl Methacrylate ◽  
Hydrogel Microspheres

Interactions between temperature-sensitive hydrogel microspheres and granulocytes

1995 ◽  
Vol 6 (7) ◽  
pp. 534-540 ◽  
Author(s):  
Koji Achiha ◽  
Rika Ojima ◽  
Yuji Kasuya ◽  
Keiji Fujimoto ◽  
Haruma Kawaguchi
Keyword(s):  
Temperature Sensitive ◽  
Temperature Sensitive Hydrogel ◽  
Hydrogel Microspheres

scholarly journals Effect of thiol-containing monomer on the preparation of temperature-sensitive hydrogel microspheres

2006 ◽  
Vol 284 (11) ◽  
pp. 1287-1292 ◽  
Author(s):  
Françoise Meunier ◽  
Christian Pichot ◽  
Abdelhamid Elaïssari
Keyword(s):  
Temperature Sensitive ◽  
Temperature Sensitive Hydrogel ◽  
Hydrogel Microspheres

Phenomenological hysteresis model for vapor-liquid phase transitions

2008 ◽  
Vol 3 (1) ◽  
pp. 5-28 ◽  
Author(s):  
Ildiko Jancskar ◽  
Amalia Ivanyi
Keyword(s):  
Phase Transitions ◽  
Liquid Phase ◽  
Hysteresis Model ◽  
Vapor Liquid

scholarly journals Crystal–liquid phase transitions in three-dimensional complex plasma under microgravity conditions

2018 ◽  
Vol 946 ◽  
pp. 012144 ◽  
Author(s):  
V N Naumkin ◽  
A M Lipaev ◽  
V I Molotkov ◽  
D I Zhukhovitskii ◽  
A D Usachev ◽  
...  
Keyword(s):  
Phase Transitions ◽  
Liquid Phase ◽  
Three Dimensional ◽  
Complex Plasma ◽  
Microgravity Conditions

scholarly journals Prion-Like Proteins in Phase Separation and Their Link to Disease

Biomolecules ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1014
Author(s):  
Macy L. Sprunger ◽  
Meredith E. Jackrel
Keyword(s):  
Protein Folding ◽  
Phase Transitions ◽  
Phase Separation ◽  
Liquid Phase ◽  
Protein Misfolding ◽  
Solid Phase ◽  
Liquid Phase Separation ◽  
Therapeutic Approaches ◽  
Important Physiological Process ◽  
Liquid Liquid Phase Separation

Aberrant protein folding underpins many neurodegenerative diseases as well as certain myopathies and cancers. Protein misfolding can be driven by the presence of distinctive prion and prion-like regions within certain proteins. These prion and prion-like regions have also been found to drive liquid-liquid phase separation. Liquid-liquid phase separation is thought to be an important physiological process, but one that is prone to malfunction. Thus, aberrant liquid-to-solid phase transitions may drive protein aggregation and fibrillization, which could give rise to pathological inclusions. Here, we review prions and prion-like proteins, their roles in phase separation and disease, as well as potential therapeutic approaches to counter aberrant phase transitions.

From the bulk to clusters: Solid-liquid phase transitions and precursor effects

1990 ◽  
Vol 24-26 (1) ◽  
pp. 283-342 ◽  
Author(s):  
R. Kofman ◽  
P. Cheyssac ◽  
R. Garrigos
Keyword(s):  
Phase Transitions ◽  
Liquid Phase ◽  
Precursor Effects ◽  
Solid Liquid

Water and its anomalies in perspective: tetrahedral liquids with and without liquid–liquid phase transitions

2000 ◽  
Vol 2 (8) ◽  
pp. 1559-1566 ◽  
Author(s):  
C. A. Angell ◽  
R. D. Bressel ◽  
M. Hemmati ◽  
E. J. Sare ◽  
J. C. Tucker
Keyword(s):  
Phase Transitions ◽  
Liquid Phase

scholarly journals Evolution of weak cooperative interactions for biological specificity

2018 ◽  
Vol 115 (47) ◽  
pp. E11053-E11060 ◽  
Author(s):  
Ang Gao ◽  
Krishna Shrinivas ◽  
Paul Lepeudry ◽  
Hiroshi I. Suzuki ◽  
Phillip A. Sharp ◽  
...  
Keyword(s):  
Phase Transitions ◽  
Liquid Phase ◽  
Evolutionary Model ◽  
Cross Reactivity ◽  
Cellular Functions ◽  
Cooperative Interactions ◽  
Lethal Mutations ◽  
Evolutionary Changes ◽  
Biological Specificity ◽  
Multicellular Organisms

A hallmark of biological systems is that particular functions and outcomes are realized in specific contexts, such as when particular signals are received. One mechanism for mediating specificity is described by Fisher’s “lock and key” metaphor, exemplified by enzymes that bind selectively to a particular substrate via specific finely tuned interactions. Another mechanism, more prevalent in multicellular organisms, relies on multivalent weak cooperative interactions. Its importance has recently been illustrated by the recognition that liquid-liquid phase transitions underlie the formation of membraneless condensates that perform specific cellular functions. Based on computer simulations of an evolutionary model, we report that the latter mechanism likely became evolutionarily prominent when a large number of tasks had to be performed specifically for organisms to function properly. We find that the emergence of weak cooperative interactions for mediating specificity results in organisms that can evolve to accomplish new tasks with fewer, and likely less lethal, mutations. We argue that this makes the system more capable of undergoing evolutionary changes robustly, and thus this mechanism has been repeatedly positively selected in increasingly complex organisms. Specificity mediated by weak cooperative interactions results in some useful cross-reactivity for related tasks, but at the same time increases susceptibility to misregulation that might lead to pathologies.

scholarly journals Viscosity Measurement of Olive Oil under Pressure

2021 ◽  
Vol 6 (5) ◽  
Author(s):  
Pawlicki LT
Keyword(s):  
Phase Transition ◽  
High Pressure ◽  
Phase Transitions ◽  
Liquid Phase ◽  
Olive Oil ◽  
Measurement Method ◽  
Viscosity Measurement ◽  
Food Preservation ◽  
Characteristic Frequencies ◽  
Viscosity Changes

This article presents changes in the viscosity of olive oil during compression. The test was carried out indirectly by measuring the dependence of the resonance frequency of the piezoelectric immersed in olive oil on pressure. For this purpose, for successive pressures, the resonance curves were read and the values of the characteristic frequencies were determined. Viscosity changes were analysed and related to the compression and crystallization taking place in the tested substance. During this research, a phase transition from the liquid phase to the alpha crystalline phase was detected, during which the resonant frequency of the tested piezoelectric reached a minimum and the viscosity related to this frequency reached a maximum. The measurement method developed in this paper can be used to detect the phase transitions of oils subjected to pressure. This may find application in the oil production and high-pressure food preservation industries for which this knowledge is essential for the safe and trouble-free use of their machines.

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