Synthesis of amphiphilic block copolymer using trimethylene carbonate bearing oligo(ethylene glycol) and investigation of thin film including cilostazol

2020 ◽  
Vol 58 (17) ◽  
pp. 2347-2354
Author(s):  
Hiroaki Nobuoka ◽  
Masakazu Nagasawa ◽  
Nalinthip Chanthaset ◽  
Hiroaki Yoshida ◽  
Yoshiaki Haramiishi ◽  
...  
Keyword(s):  
Thin Film ◽  
Block Copolymer ◽  
Ethylene Glycol ◽  
Amphiphilic Block Copolymer ◽  
Trimethylene Carbonate

scholarly journals Key Factor Study for Amphiphilic Block Copolymer‐Templated Mesoporous SnO 2 Thin Film Synthesis: Influence of Solvent and Catalyst

2020 ◽  
Vol 7 (18) ◽  
pp. 2001002
Author(s):  
Shanshan Yin ◽  
Ting Tian ◽  
Kerstin S. Wienhold ◽  
Christian L. Weindl ◽  
Renjun Guo ◽  
...  
Keyword(s):  
Thin Film ◽  
Block Copolymer ◽  
Amphiphilic Block Copolymer ◽  
Factor Study ◽  
Key Factor ◽  
Film Synthesis ◽  
Influence Of Solvent

Methoxy-Poly(ethylene glycol)-block-Poly(ε-caprolactone) Bearing Pendant Aldehyde Groups as pH-Responsive Drug Delivery Carrier

2013 ◽  
Vol 66 (12) ◽  
pp. 1576 ◽  
Author(s):  
Gejun Ma ◽  
Deshan Li ◽  
Ji Wang ◽  
Xuefei Zhang ◽  
Haoyu Tang
Keyword(s):  
Drug Delivery ◽  
Block Copolymer ◽  
Ethylene Glycol ◽  
In Vitro Release ◽  
Amphiphilic Block Copolymer ◽  
Poly Ethylene Glycol ◽  
Ph Change ◽  
Poly Ethylene ◽  
Aldehyde Groups

A biodegradable amphiphilic block copolymer of methoxy poly(ethylene glycol)-block-poly(ϵ-caprolactone) bearing pendant aldehyde groups was synthesised by a combination of ring-opening polymerisation and thio-bromo ‘click’ chemistry. The free aldehyde groups on the copolymer were reacted with hydrophobic payloads (p-methoxylaniline as a model drug) by a benzoic–imine linker, which was responsive to pH change. NMR, FTIR, and gel permeation chromatography analysis confirmed the copolymer structures. In vitro release studies revealed that under acid stimulus, hydrolysis of the benzoic–imine bond resulted in a rapid drug release. This new amphiphilic block copolymer is expected to have promising applications in biodegradable controlled drug delivery systems.

scholarly journals Molecular Orientation of Amphiphilic Block Copolymer of Poly (peptide-co-ethylene glycol) at Air-Water Interface.

2000 ◽  
Vol 56 (5) ◽  
pp. 221-226 ◽  
Author(s):  
Tomikiyo Doi ◽  
Takatoshi Kinoshita ◽  
Yoshiharu Tsujita ◽  
Hiroaki Yoshimizu
Keyword(s):  
Block Copolymer ◽  
Ethylene Glycol ◽  
Molecular Orientation ◽  
Amphiphilic Block Copolymer ◽  
Water Interface ◽  
Air Water Interface
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