Characterization of human neural differentiation from pluripotent stem cells using proteomics/PTMomics-Current state-of-the-art and challenges

PROTEOMICS ◽  
2015 ◽  
Vol 15 (4) ◽  
pp. 656-674 ◽  
Author(s):  
Marcella Nunes Melo-Braga ◽  
Morten Meyer ◽  
Xianmin Zeng ◽  
Martin Røssel Larsen
Keyword(s):  
Stem Cells ◽  
Pluripotent Stem Cells ◽  
Neural Differentiation ◽  
State Of The Art ◽  
Current State

scholarly journals Brain organoids and insights on human evolution

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 760 ◽  
Author(s):  
Alysson R. Muotri
Keyword(s):  
Stem Cells ◽  
Human Brain ◽  
Human Health ◽  
Human Evolution ◽  
Pluripotent Stem Cells ◽  
Disease Modeling ◽  
State Of The Art ◽  
Future Perspectives ◽  
Promising Technique ◽  
Current State

Human brain organoids, generated from pluripotent stem cells, have emerged as a promising technique for modeling early stages of human neurodevelopment in controlled laboratory conditions. Although the applications for disease modeling in a dish have become routine, the use of these brain organoids as evolutionary tools is only now getting momentum. Here, we will review the current state of the art on the use of brain organoids from different species and the molecular and cellular insights generated from these studies. Besides, we will discuss how this model might be beneficial for human health and the limitations and future perspectives of this technology.

Derivation and Characterization of human Induced Pluripotent Stem Cells

Acta Naturae ◽  
2009 ◽  
Vol 1 (2) ◽  
pp. 91-92 ◽  
Author(s):  
M V Shutova ◽  
A N Bogomazova ◽  
M A Lagarkova ◽  
S L Kiselev
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Induced Pluripotent

scholarly journals Generation and characterization of human induced pluripotent stem cells (iPSCs) from three male and three female patients with CDKL5 Deficiency Disorder (CDD)

2021 ◽  
Vol 53 ◽  
pp. 102276
Author(s):  
Pin-Fang Chen ◽  
Teresa Chen ◽  
Taylor E. Forman ◽  
Amanda C. Swanson ◽  
Benjamin O'Kelly ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Female Patients ◽  
Induced Pluripotent

Characterization of hematopoietic cells generated from normal and leukemic human induced pluripotent stem cells (hiPSCs) in teratomas

2017 ◽  
Vol 53 ◽  
pp. S80-S81
Author(s):  
Margarita MacAldaz ◽  
Bardia AbolHasani ◽  
Paul Miller ◽  
Melanie Kardel ◽  
Karl Welte ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Hematopoietic Cells ◽  
Induced Pluripotent
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