Exploring analytical proteomics platforms toward the definition of human cardiac stem cells receptome

PROTEOMICS ◽  
2015 ◽  
Vol 15 (7) ◽  
pp. 1332-1337 ◽  
Author(s):  
Patrícia Gomes-Alves ◽  
Margarida Serra ◽  
Catarina Brito ◽  
Luis R.-Borlado ◽  
Juan A. López ◽  
...  
2013 ◽  
Vol 40 (10) ◽  
pp. 1070
Author(s):  
Cui-Mi DUAN ◽  
Hong-Yu SUN ◽  
Ye YUAN ◽  
Zhi-Qiang LIU ◽  
Rong-Yu TANG ◽  
...  

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Markus Hengstschläger ◽  
Margit Rosner

AbstractIt is known that in countries, in which basic research on human embryos is in fact prohibited by law, working with imported human embryonic stem cells (hESCs) can still be permitted. As long as hESCs are not capable of development into a complete human being, it might be the case that they do not fulfill all criteria of the local definition of an embryo. Recent research demonstrates that hESCs can be developed into entities, called embryoids, which increasingly could come closer to actual human embryos in future. By discussing the Austrian situation, we want to highlight that current embryoid research could affect the prevailing opinion on the legal status of work with hESCs and therefore calls for reassessment of the regulations in all countries with comparable definitions of the embryo.


Author(s):  
Nicola Alessio ◽  
Anna Lisa Brigida ◽  
Gianfranco Peluso ◽  
Nicola Antonucci ◽  
Umberto Galderisi ◽  
...  

Neurodevelopmental lifelong pathologies defined by problems with social interaction, communication capacity and presence of repetitive/stereotyped clusters of behavior and interests are grouped under the definition of autism spectrum disorder (ASD). ASD prevalence is still increasing, indicating the need to identify specific biomarkers and novel pharmacotherapies. Neuroinflammation and neuro-immune cross-talk dysregulation are specific hallmarks of ASD, offering the possibility of treating these disorders by stem cell therapy. Indeed, cellular strategies have been postulated, proposed and applied to ASD. However, less is known about the molecular action mechanisms of stem cells. As a possibility, the positive and restorative effects mediated by stem cells could be due to their paracrine activity, by which stem cells produce and release several ameliorative and anti-inflammatory molecules. Among the secreted complex tools, exosomes are sub-organelles, enriched by RNA and proteins, that provide cell-to-cell communication. Exosomes could be the mediators of many stem cell-associated therapeutic activities. This review article describes the potential role of exosomes in alleviating ASD symptoms.


Small ◽  
2012 ◽  
Vol 8 (17) ◽  
pp. 2752-2756 ◽  
Author(s):  
Thibaud Magouroux ◽  
Jerome Extermann ◽  
Pernilla Hoffmann ◽  
Yannick Mugnier ◽  
Ronan Le Dantec ◽  
...  

2010 ◽  
Vol 3 (7) ◽  
pp. 772-775 ◽  
Author(s):  
Mariann Gyöngyösi ◽  
Rayyan Hemetsberger ◽  
Susanne Wolbank ◽  
Christoph Kaun ◽  
Aniko Posa ◽  
...  

2012 ◽  
Vol 16 (11) ◽  
pp. 2549-2563 ◽  
Author(s):  
Zhuzhi Wen ◽  
Zun Mai ◽  
Haifeng Zhang ◽  
Yangxin Chen ◽  
Dengfeng Geng ◽  
...  

2011 ◽  
Vol 57 (14) ◽  
pp. E1014
Author(s):  
Behzad Nasehi Oskouei ◽  
Guillaume Lamirault ◽  
Chacko Joseph ◽  
Stephanie Landa ◽  
Marc Dauer ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document