Changes in muscle proteomics in the course of the Caudwell Research Expedition to Mt. Everest

PROTEOMICS ◽  
2014 ◽  
Vol 15 (1) ◽  
pp. 160-171 ◽  
Author(s):  
Denny Z. H. Levett ◽  
Agnese Viganò ◽  
Daniele Capitanio ◽  
Michele Vasso ◽  
Sara De Palma ◽  
...  
Keyword(s):  
Muscle Proteomics

Comparative muscle proteomics/phosphoproteomics analysis provides new insight for the biosafety evaluation of fat-1 transgenic cattle

2017 ◽  
Vol 26 (5) ◽  
pp. 625-638 ◽  
Author(s):  
Xiangbo Xin ◽  
Xinfeng Liu ◽  
Xin Li ◽  
Xiangbin Ding ◽  
Shuping Yang ◽  
...  
Keyword(s):  
Transgenic Cattle ◽  
Muscle Proteomics ◽  
Biosafety Evaluation

Muscle proteomics profiles in sheep: the effect of breed and nutritional status

2012 ◽  
pp. 126-129
Author(s):  
André M. de Almeida ◽  
Rui M. G. Palhinhas ◽  
Tanya Kilminster ◽  
Tim Scanlon ◽  
Johan Greeff ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Muscle Proteomics

scholarly journals Skeletal muscle proteomics in livestock production

2010 ◽  
Vol 9 (3) ◽  
pp. 259-278 ◽  
Author(s):  
B. Picard ◽  
C. Berri ◽  
L. Lefaucheur ◽  
C. Molette ◽  
T. Sayd ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Livestock Production ◽  
Muscle Proteomics

scholarly journals Aging Skeletal Muscle Proteomics Finds Changes in Spliceosome, Immune factors, Proteostasis and Mitochondria

2019 ◽  
Author(s):  
Ceereena Ubaida-Mohien ◽  
Alexey Lyashkov ◽  
Marta Gonzalez-Freire ◽  
Ravi Tharakan ◽  
Michelle Shardell ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Alternative Splicing ◽  
Ribosomal Proteins ◽  
Older Persons ◽  
Molecular Mechanisms ◽  
Tca Cycle ◽  
Energetic Metabolism ◽  
Proteomic Data ◽  
The Tca Cycle ◽  
Muscle Proteomics

AbstractA progressive decline of skeletal muscle strength with aging is a primary cause of mobility loss and frailty in older persons, but the molecular mechanisms of such decline are not fully understood. Here, using quantitative discovery proteomic data from skeletal muscle specimens collected from 58 healthy persons aged 20 to 87 years show that ribosomal proteins and proteins related to energetic metabolism, including those related to the TCA cycle, mitochondria respiration, and glycolysis were underrepresented in older persons. Proteins with important roles in innate and adaptive immunity, involved in proteostasis and regulation of alternative splicing were all overrepresented in muscle from older persons. Changes with aging of alternative splicing were confirmed by RNA-seq. Overall, older muscle has a profound deficit of energetic metabolism, a pro-inflammatory environment and increased proteostasis. Upregulation of the splicing machinery maybe an attempt to compensate for these changes and this could be tested in future studies.

Rabbit muscle proteomics: A great leap forward

PROTEOMICS ◽  
2013 ◽  
Vol 13 (15) ◽  
pp. 2225-2226 ◽  
Author(s):  
André Martinho de Almeida
Keyword(s):  
Rabbit Muscle ◽  
Great Leap ◽  
Great Leap Forward ◽  
Muscle Proteomics
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