Identification of complement C3f-desArg and its derivative for acute leukemia diagnosis and minimal residual disease assessment

PROTEOMICS ◽  
2010 ◽  
Vol 10 (1) ◽  
pp. 90-98 ◽  
Author(s):  
Tingting Liang ◽  
Na Wang ◽  
Wei Li ◽  
Ailing Li ◽  
Jie Wang ◽  
...  
Keyword(s):  
Acute Leukemia ◽  
Minimal Residual Disease ◽  
Residual Disease ◽  
Disease Assessment ◽  
Leukemia Diagnosis ◽  
Minimal Residual

Post-transplant minimal residual disease assessment in Multiple myeloma

2019 ◽  
Vol 19 (10) ◽  
pp. e180
Author(s):  
Anjali Mookerjee ◽  
Meetu Dahiya ◽  
Ritu Gupta ◽  
Rakesh Kumar ◽  
Atul Sharma ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Minimal Residual Disease ◽  
Residual Disease ◽  
Disease Assessment ◽  
Post Transplant ◽  
Minimal Residual

Flow cytometric minimal residual disease assessment of peripheral blood in acute lymphoblastic leukaemia patients has potential for early detection of relapsed extramedullary disease

2018 ◽  
Vol 71 (7) ◽  
pp. 653-658 ◽  
Author(s):  
Alissa Keegan ◽  
Karry Charest ◽  
Ryan Schmidt ◽  
Debra Briggs ◽  
Daniel J Deangelo ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukaemia ◽  
Minimal Residual Disease ◽  
Lymphoblastic Leukaemia ◽  
Peripheral Blood ◽  
Residual Disease ◽  
Diagnostic Value ◽  
Disease Assessment ◽  
Extramedullary Disease ◽  
Systemic Relapse ◽  
Minimal Residual

ObjectivesTo evaluate peripheral blood (PB) for minimal residual disease (MRD) assessment in adults with acute lymphoblastic leukaemia (ALL).MethodsWe analysed 76 matched bone marrow (BM) aspirate and PB specimens independently for the presence of ALL MRD by six-colour flow cytometry (FC).ResultsThe overall rate of BM MRD-positivity was 24% (18/76) and PB was also MRD-positive in 22% (4/18) of BM-positive cases. We identified two cases with evidence of leukaemic cells in PB at the time of the extramedullary relapse that were interpreted as MRD-negative in BM.ConclusionsThe use of PB MRD as a non-invasive method for monitoring of systemic relapse may have added clinical and diagnostic value in patients with high risk of extramedullary disease.

scholarly journals Flow cytometric determination of atypical antigen expression in acute leukemia for the study of minimal residual disease

Cytometry ◽  
1992 ◽  
Vol 13 (8) ◽  
pp. 893-901 ◽  
Author(s):  
Johannes Drach ◽  
Doris Drach ◽  
Herta Glassl ◽  
Claus Gattringer ◽  
Heinz Huber
Keyword(s):  
Acute Leukemia ◽  
Minimal Residual Disease ◽  
Residual Disease ◽  
Antigen Expression ◽  
Flow Cytometric ◽  
Minimal Residual
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