Two-dimensional proteome reference maps for the human pathogenic filamentous fungus Aspergillus fumigatus

PROTEOMICS ◽  
2009 ◽  
Vol 9 (5) ◽  
pp. 1407-1415 ◽  
Author(s):  
Martin Vödisch ◽  
Daniela Albrecht ◽  
Franziska Leßing ◽  
André D. Schmidt ◽  
Robert Winkler ◽  
...  
Keyword(s):  
Aspergillus Fumigatus ◽  
Filamentous Fungus ◽  
Two Dimensional ◽  
Proteome Reference Maps

scholarly journals Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring

2021 ◽  
Vol 7 (1) ◽  
pp. 30
Author(s):  
François Danion ◽  
Norman van Rhijn ◽  
Alexandre C. Dufour ◽  
Rachel Legendre ◽  
Odile Sismeiro ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Aspergillus Fumigatus ◽  
Filamentous Fungus ◽  
Fungal Species ◽  
Conidial Germination ◽  
Biological Cycle ◽  
Gene Deletions ◽  
Airborne Conidia ◽  
Nutritional Environment ◽  
Germination Parameters

Establishment of a fungal infection due to Aspergillus fumigatus relies on the efficient germination of the airborne conidia once they penetrate the respiratory tract. However, the features of conidial germination have been poorly explored and understood in this fungal species as well as in other species of filamentous fungi. We show here that the germination of A. fumigatus is asynchronous. If the nutritional environment and extensive gene deletions can modify the germination parameters for A. fumigatus, the asynchrony is maintained in all germinative conditions tested. Even though the causes for this asynchrony of conidial germination remain unknown, asynchrony is essential for the completion of the biological cycle of this filamentous fungus.

scholarly journals Erratum: Corrigendum: Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

Nature ◽  
2006 ◽  
Vol 439 (7075) ◽  
pp. 502-502 ◽  
Author(s):  
William C. Nierman ◽  
Arnab Pain ◽  
Michael J. Anderson ◽  
Jennifer R. Wortman ◽  
H. Stanley Kim ◽  
...  
Keyword(s):  
Aspergillus Fumigatus ◽  
Filamentous Fungus ◽  
Genomic Sequence

scholarly journals Two New Spiro-Heterocyclic γ-Lactams from A Marine-Derived Aspergillus fumigatus Strain CUGBMF170049

Marine Drugs ◽  
2019 ◽  
Vol 17 (5) ◽  
pp. 289 ◽  
Author(s):  
Xiuli Xu ◽  
Jiahui Han ◽  
Yanan Wang ◽  
Rui Lin ◽  
Haijin Yang ◽  
...  
Keyword(s):  
Spectral Analysis ◽  
Circular Dichroism ◽  
Aspergillus Fumigatus ◽  
2D Nmr ◽  
Two Dimensional ◽  
One Dimensional ◽  
Helvolic Acid ◽  
Circular Dichroïsm

Two new spiro-heterocyclic γ-lactam derivatives, cephalimysins M (1) and N (2), were isolated from the fermentation cultures of the marine-derived fungus Aspergillus fumigatus CUGBMF17018. Two known analogues, pseurotin A (3) and FD-838 (4), as well as four previously reported helvolic acid derivatives, 16-O-propionyl-16-O-deacetylhelvolic acid (5), 6-O-propionyl-6-O-deacetylhelvolic acid (6), helvolic acid (7), and 1,2-dihydrohelvolic acid (8) were also identified. One-dimensional (1D), two-dimensional (2D) NMR, HRMS, and circular dichroism spectral analysis characterized the structures of the isolated compounds.

Construction of quantitative proteome reference maps of mouse spleen and lymph node based on two-dimensional gel electrophoresis

PROTEOMICS ◽  
2006 ◽  
Vol 6 (13) ◽  
pp. 3833-3844 ◽  
Author(s):  
Yayoi Kimura ◽  
Ryo Yokoyama ◽  
Yuri Ishizu ◽  
Toshio Nishigaki ◽  
Yasuaki Murahashi ◽  
...  
Keyword(s):  
Lymph Node ◽  
Gel Electrophoresis ◽  
Mouse Spleen ◽  
Two Dimensional ◽  
Two Dimensional Gel Electrophoresis ◽  
Proteome Reference Maps

scholarly journals Calcineurin Localizes to the Hyphal Septum in Aspergillus fumigatus: Implications for Septum Formation and Conidiophore Development

2008 ◽  
Vol 7 (9) ◽  
pp. 1606-1610 ◽  
Author(s):  
Praveen Rao Juvvadi ◽  
Jarrod R. Fortwendel ◽  
Nadthanan Pinchai ◽  
B. Zachary Perfect ◽  
Joseph Heitman ◽  
...  
Keyword(s):  
Green Fluorescent Protein ◽  
Aspergillus Fumigatus ◽  
Filamentous Fungus ◽  
Enhanced Green Fluorescent Protein ◽  
Fluorescent Protein ◽  
Dependent Manner ◽  
Septum Formation ◽  
Calcineurin A ◽  
Green Fluorescent

ABSTRACT A functional calcineurin A fusion to enhanced green fluorescent protein (EGFP), CnaA-EGFP, was expressed in the Aspergillus fumigatus ΔcnaA mutant. CnaA-EGFP localized in actively growing hyphal tips, at the septa, and at junctions between the vesicle and phialides in an actin-dependent manner. This is the first study to implicate calcineurin in septum formation and conidiophore development of a filamentous fungus.

scholarly journals Screening of Chemical Libraries for New Antifungal Drugs against Aspergillus fumigatus Reveals Sphingolipids Are Involved in the Mechanism of Action of Miltefosine

mBio ◽  
2021 ◽  
Author(s):  
Thaila Fernanda dos Reis ◽  
Maria Augusta Crivelente Horta ◽  
Ana Cristina Colabardini ◽  
Caroline Mota Fernandes ◽  
Lilian Pereira Silva ◽  
...  
Keyword(s):  
Aspergillus Fumigatus ◽  
Mechanism Of Action ◽  
Filamentous Fungus ◽  
Antifungal Drugs ◽  
Clinical Isolates ◽  
Content Type ◽  
Chemical Libraries

The filamentous fungus Aspergillus fumigatus causes a group of diseases named aspergillosis, and their development occurs after the inhalation of conidia dispersed in the environment. Very few classes of antifungal drugs are available for aspergillosis treatment, e.g., azoles, but the emergence of global resistance to azoles in A. fumigatus clinical isolates has increased over recent decades.

scholarly journals Draft Genome Sequence of the Pathogenic Filamentous Fungus Aspergillus lentulus IFM 54703 T

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Yoko Kusuya ◽  
Kanae Sakai ◽  
Katsuhiko Kamei ◽  
Hiroki Takahashi ◽  
Takashi Yaguchi
Keyword(s):  
Aspergillus Fumigatus ◽  
Genome Sequence ◽  
Causative Agent ◽  
Sibling Species ◽  
Filamentous Fungus ◽  
Draft Genome ◽  
Draft Genome Sequence ◽  
Aspergillus Lentulus ◽  
First Time

Aspergillus lentulus , a sibling species of Aspergillus fumigatus , has been reported as a causative agent of aspergillosis, and exhibited low susceptibility to azole. Here, we present the draft genome sequence of A. lentulus strain IFM 54703 T for the first time.

scholarly journals Cloning and characterization of a sialidase from the filamentous fungus, Aspergillus fumigatus

2010 ◽  
Vol 27 (5) ◽  
pp. 533-548 ◽  
Author(s):  
Mark L. Warwas ◽  
Juliana H. F. Yeung ◽  
Deepani Indurugalla ◽  
Arne Ø. Mooers ◽  
Andrew J. Bennet ◽  
...  
Keyword(s):  
Aspergillus Fumigatus ◽  
Filamentous Fungus
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