Analysis of the wheat andPuccinia triticina (leaf rust) proteomes during a susceptible host-pathogen interaction

PROTEOMICS ◽  
2006 ◽  
Vol 6 (6) ◽  
pp. 1897-1907 ◽  
Author(s):  
Christof Rampitsch ◽  
Natalia V. Bykova ◽  
Brent McCallum ◽  
Eva Beimcik ◽  
Werner Ens
Keyword(s):  
Leaf Rust ◽  
Susceptible Host ◽  
Host Pathogen Interaction ◽  
Host Pathogen

scholarly journals Extinction of Disease Pathogenesis in Infected Population and Its Subsequent Recovery: A Stochastic Approach

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Priti Kumar Roy ◽  
Jayanta Mondal ◽  
Rupa Bhattacharyya ◽  
Sabyasachi Bhattacharya ◽  
Tamas Szabados
Keyword(s):  
Optimal Control ◽  
Stochastic Approach ◽  
Research Paper ◽  
Host Population ◽  
Disease Pathogenesis ◽  
Susceptible Host ◽  
Host Pathogen Interaction ◽  
Infected Population ◽  
Time To Extinction ◽  
Host Pathogen

A stochastic mathematical model of host-pathogen interaction has been developed to estimate the time to extinction of infected population. It has been assumed in the model that the infected host does not grow or reproduce but can recover from pathogenic infection and move to add to the susceptible host population using various drugs or vaccination. Extinction of infected population in host-pathogen interaction depends significantly upon the total population. Here, we consider an extension of our previous work with the stochastic approach to predict the time to extinction of disease pathogenesis. The optimal control approach helped in designing an innovative, safe therapeutic regimen where the susceptible host population enhanced with simultaneous decrease in the infected population. By means of an optimal control theory paradigm, it has also been shown in our preceding research paper that the cost-effective combination of treatment may depend on the population size. In this research paper, we have studied an approximation which is derived in favor of quasi-stationary distribution along with the expected time to extinction for the model of host-pathogen interactions. The complete study has been roofed through the stochastic approach in context that disease pathogenesis is to be extinct and infected population are going to be recovered. Numerical simulation is also done to confirm the analysis.

scholarly journals The Role of Macrophages in the Host’s Defense against Sporothrix schenckii

Pathogens ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 905
Author(s):  
Estela Ruiz-Baca ◽  
Armando Pérez-Torres ◽  
Yolanda Romo-Lozano ◽  
Daniel Cervantes-García ◽  
Carlos A. Alba-Fierro ◽  
...  
Keyword(s):  
Immune Responses ◽  
Macrophage Polarization ◽  
Sporothrix Schenckii ◽  
Macrophage Cell ◽  
Cell Recruitment ◽  
Host Pathogen Interaction ◽  
Interaction Processes ◽  
Host Pathogen ◽  
Molecular Patterns

The role of immune cells associated with sporotrichosis caused by Sporothrix schenckii is not yet fully clarified. Macrophages through pattern recognition receptors (PRRs) can recognize pathogen-associated molecular patterns (PAMPs) of Sporothrix, engulf it, activate respiratory burst, and secrete pro-inflammatory or anti-inflammatory biological mediators to control infection. It is important to consider that the characteristics associated with S. schenckii and/or the host may influence macrophage polarization (M1/M2), cell recruitment, and the type of immune response (1, 2, and 17). Currently, with the use of new monocyte-macrophage cell lines, it is possible to evaluate different host–pathogen interaction processes, which allows for the proposal of new mechanisms in human sporotrichosis. Therefore, in order to contribute to the understanding of these host–pathogen interactions, the aim of this review is to summarize and discuss the immune responses induced by macrophage-S. schenckii interactions, as well as the PRRs and PAMPs involved during the recognition of S. schenckii that favor the immune evasion by the fungus.

scholarly journals Host–Pathogen Interaction in Invasive Salmonellosis

2012 ◽  
Vol 8 (10) ◽  
pp. e1002933 ◽  
Author(s):  
Hanna K. de Jong ◽  
Chris M. Parry ◽  
Tom van der Poll ◽  
W. Joost Wiersinga
Keyword(s):  
Host Pathogen Interaction ◽  
Host Pathogen

scholarly journals Transcriptional response ofNautella italicaR11 towards its macroalgal host uncovers new mechanisms of host-pathogen interaction

2017 ◽  
Vol 27 (8) ◽  
pp. 1820-1832 ◽  
Author(s):  
Jennifer Hudson ◽  
Melissa Gardiner ◽  
Nandan Deshpande ◽  
Suhelen Egan
Keyword(s):  
Transcriptional Response ◽  
Host Pathogen Interaction ◽  
Host Pathogen
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