Mitochondrial proteome: Altered cytochromec oxidase subunit levels in prostate cancer

PROTEOMICS ◽  
2003 ◽  
Vol 3 (9) ◽  
pp. 1801-1810 ◽  
Author(s):  
Paul C. Herrmann ◽  
John W. Gillespie ◽  
Lu Charboneau ◽  
Verena E. Bichsel ◽  
Cloud P. Paweletz ◽  
...  
PROTEOMICS ◽  
2004 ◽  
Vol 4 (9) ◽  
pp. 2789-2795 ◽  
Author(s):  
René C. Krieg ◽  
Ruth Knuechel ◽  
Elliot Schiffmann ◽  
Lance A. Liotta ◽  
Emanuel F. Petricoin ◽  
...  

1998 ◽  
Vol 43 (1) ◽  
pp. 110-116 ◽  
Author(s):  
Giacomo P. Comi ◽  
Andreina Bordoni ◽  
Sabrina Salani ◽  
Liliana Franceschina ◽  
Monica Sciacco ◽  
...  

Scientifica ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Takara A. Scott ◽  
Rebecca S. Arnold ◽  
John A. Petros

Purpose. Mitochondrial DNA (mtDNA) mutations have been described in every adult neoplasm including prostate cancer. There are marked racial differences in mutations within the cytochrome c oxidase subunit 1 (COI) gene in individuals with prostate cancer (PCa). The purpose of this study was to identify the variation in COI gene sequence in African and Caucasian Americans with prostate cancer.Methods. We sequenced the COI gene from peripheral blood in 482 prostate cancer patients and 189 controls. All bases that differed from the revised Cambridge Reference Sequence (rCRS) were classified as either silent or missense and the compiled alterations were then compared between races and published reports.Results and Conclusions. We found inherited mtDNA COI missense variants in 8.8% of Caucasian prostate cancer patients (vs. 0.0% controls) and 72.8% of African-American prostate cancer patients (vs. 64.3% controls) A total of 144 COI variants were identified, of which 30 were missense mutations. Of 482 PCa patients, 116 (24.1%) had one or more missense mutations. Further evaluation of this gene and these mutations may allow for the identification of genetically at-risk populations. The high rate of COI mutations in African-Americans may account for some of the racial disparity observed in prostate cancer.


2018 ◽  
Vol 29 (4) ◽  
pp. 175-183
Author(s):  
Marko Nieminen ◽  
Christer Hansson ◽  
Mari Kekkonen ◽  
Veli Vikberg

Mesopolobus incultus auct. is hypothesized to consist of twodifferent species, M. amyntor (Walker) and M. incultus (Walker). This hypothesis is supported bymolecular(cytochromec oxidase subunit I, i.e. COI), morphological and biologicaldata.Mesopolobus amyntor is a primary parasitoid of Mecinus pascuorum (Gyllenhal) and M. labilis (Herbst) (Coleoptera: Curculionidae) on Plantago lanceolata. Mesopolobus incultus is a primary parasitoid of Protapion fulvipes (Geoffroy) (Coleoptera: Apionidae) on Trifolium repens and T. pratense, and hasalso been inferred to act as a secondary parasitoid (hyperparasitoid) of Spintherus dubius (Nees) (Hymenoptera: Pteromalidae) or Bruchophagus gibbus (Boheman) (Hymenoptera: Eurytomidae). The results of this study lead to following nomenclatural changes: M. amyntor is removed from synonymy under M. incultus, and Pteromalus urgo, P. belesis and P. berecynthos, all described by Walker, are synonymized under M. amyntor. The species are diagnosed with characters illustrated.


2001 ◽  
Vol 120 (5) ◽  
pp. A284-A284
Author(s):  
T BOLIN ◽  
A KNEEBONE ◽  
T LARSSON
Keyword(s):  

2007 ◽  
Vol 177 (4S) ◽  
pp. 538-539
Author(s):  
Joseph F. Pazona ◽  
C. Shad Thaxton ◽  
Neema Navai ◽  
Brian T. Helfand ◽  
Lee C. Zhao ◽  
...  
Keyword(s):  

2007 ◽  
Vol 177 (4S) ◽  
pp. 77-78
Author(s):  
Christopher R. Porter ◽  
Jochen Walz ◽  
Andrea Gallina ◽  
Claudio Jeldres ◽  
Koichi Kodama ◽  
...  

2007 ◽  
Vol 177 (4S) ◽  
pp. 156-156
Author(s):  
Andrea Salonia ◽  
Pierre I. Karakiewicz ◽  
Andrea Gallina ◽  
Alberto Briganti ◽  
Tommaso C. Camerata ◽  
...  

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