Relationships between treatments received in the Nottingham Study of Neurotic Disorder over 30 years and personality status

Author(s):  
Peter Tyrer ◽  
Helen Tyrer ◽  
Min Yang
Keyword(s):  
2011 ◽  
Vol 189 (1) ◽  
pp. 121-127 ◽  
Author(s):  
Matthias Vogel ◽  
Johanna Meier ◽  
Stephanie Grönke ◽  
Marco Waage ◽  
Wolfgang Schneider ◽  
...  

The Lancet ◽  
1998 ◽  
Vol 352 (9141) ◽  
pp. 1706-1707 ◽  
Author(s):  
Adrian Eichenberger ◽  
Dominique Eich ◽  
Wulf Rössler ◽  
Jules Angst

1981 ◽  
Vol 138 (2) ◽  
pp. 110-118 ◽  
Author(s):  
T. Berney ◽  
I. Kolvin ◽  
S. R. Bhate ◽  
R. F. Garside ◽  
J. Jeans ◽  
...  

SummaryA double-blind trial failed to demonstrate any significant short-term effects of clomipramine in doses recommended for use in general practice (in addition to the usual range of psychotherapeutic help) in the treatment of children with school refusal and neurotic disorder. Patterns of improvement were also studied for the sample as a whole irrespective of treatment. Neither age nor sex were significantly related to improvement, except on one behavioural measure where girls initially did better than boys. In addition, it was found that there was a rapid relief of depression but neurotic symptomatology tended to persist.


The Lancet ◽  
1998 ◽  
Vol 352 (9128) ◽  
pp. 605-609 ◽  
Author(s):  
Glyn Lewis ◽  
Paul Bebbington ◽  
Traolach Brugha ◽  
Michael Farrell ◽  
Baljit Gill ◽  
...  

The Lancet ◽  
1988 ◽  
Vol 332 (8618) ◽  
pp. 1015 ◽  
Author(s):  
DonaldF. Klein ◽  
P. Tyrer ◽  
N. Seivewright ◽  
B. Ferguson ◽  
J. Brothwell ◽  
...  
Keyword(s):  

1998 ◽  
Vol 28 (5) ◽  
pp. 1149-1157 ◽  
Author(s):  
H. SEIVEWRIGHT ◽  
P. TYRER ◽  
T. JOHNSON

Background. There have been no previous studies of the outcome of different neurotic disorders in which a prospective group with original randomization to treatment have been followed up over a long period. Such studies are important in identifying the factors associated with good and poor outcome.Methods. A 5-year follow-up assessment was made of a cohort of 210 psychiatric out-patients seen in general practice psychiatric clinics with a DSM-III diagnosis of generalized anxiety disorder (71), panic disorder (74) or dysthymic disorder (65) and randomized to drug treatment, cognitive and behaviour therapy, and self-help. A total of 182 of the patients (87%) were assessed after 5 years by examination of hospital and GP records using a standardized procedure and outcome determined with a four-point outcome scale.Results. One hundred and seven (60%) of the patients had a favourable outcome but the remainder continued to be handicapped either intermittently or continuously throughout the 5-year period. Analysis of the value of initial data in predicting outcome using polychotomous step-wise logistic regression revealed that five variables were significant predictors of poor prognosis: older age; recurrent episodes; the presence of personality disorder at entry; general neurotic syndrome at entry; and symptom severity after 10 weeks. The initial DSM diagnosis and original treatment given, together with ten other variables, were of no predictive value.Conclusions. The long-term outcome of neurotic disorder is better predicted by age, personality and recency of onset than by other clinical variables with the exception of initial response to treatment.


2005 ◽  
Vol 112 (3) ◽  
pp. 224-232 ◽  
Author(s):  
G. Knerer ◽  
S. Byford ◽  
T. Johnson ◽  
H. Seivewright ◽  
P. Tyrer
Keyword(s):  

2007 ◽  
Vol 60 (7-8) ◽  
pp. 365-371
Author(s):  
Predrag Djuric ◽  
Danka Filipovic

Different aspects of driver personality may affect traffic safety. Extended driver reaction time causes deceleration of the reflexes, which is a major cause of traffic accidents. Cornell index was used in 30 drivers responsible for traffic accidents, with the aim to measure their level of neurotic disorder and compare them with results of controls (drivers not responsible for traffic accidents). Reaction time was measured and compared among subjects with normal results of Cornell test and those with pathological findings. Drivers causing traffic accidents showed significantly higher Cornell index scores than drivers not responsible for traffic accidents. Drivers with pathological results of Cornell index showed a significantly longer reaction time.


2003 ◽  
Vol 15 (1-2) ◽  
pp. 91-96 ◽  
Author(s):  
G. Lewis ◽  
P. Bebbington ◽  
T. Brugha ◽  
M. Farrell ◽  
B. Gill ◽  
...  

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