Mapping the road from childhood adversity to personality disorder: The role of unresolved states of mind

Dramatic advances in therapy for pulmonary arterial hypertension (PAH) in the last 20 years have improved survival from a median of 2.5 years in the pretreatment era to 7.5 years currently. However, impressive as that may seem, it is important to note that a median survival of 7.5 years is equivalent to that of surgically resected non-small cell lung cancer, thus underscoring the importance of lung transplantation as a treatment option in patients with PAH. In this edition of Advances, Edelman has reviewed the pathway to transplantation for patients with PAH, detailing the recommendations for timing of referral, listing for lung transplantation, the role of the lung allocation score in allocating a donor organ, and the outcome of lung transplantation.

Download Full-text

The Role of Geo-location Technologies

10.1093/oso/9780198795674.003.0011 ◽

2017 ◽

Author(s):

Dan Jerker B. Svantesson

Keyword(s):

International Law ◽

Law Reform ◽

Private International Law ◽

Current Effect ◽

Public International Law ◽

The Road ◽

On The Road

This chapter explores the role geo-location technologies may play on the road towards achieving jurisdictional interoperability. The relevant technologies involved are introduced briefly, their accuracy examined, and an overview is provided of their use, including the increasingly common use of so-called geo-blocking. Attention is then given to perceived and real concerns stemming from the use of geo-location technologies and how these technologies impact international law, territoriality, and sovereignty, as well as to the role these technologies may play in law reform. The point is made that the current ‘effect-focused’ rules in both private international law and public international law (as those disciplines are traditionally defined), are likely to continue to work as an incentive for the use of geo-location technologies.

Download Full-text

The Limits of Language as the Limits of the World: Cormac McCarthy’s and David Markson’s Post-Apocalyptic Novels

Text Matters ◽

10.1515/texmat-2015-0006 ◽

2015 ◽

pp. 62-78 ◽

Cited By ~ 1

Author(s):

Paulina Ambroży

Keyword(s):

Human Values ◽

The Road ◽

The World

The article examines the correlation between the world and the word in two novels which engage with a post-apocalyptic scenario: David Markson’s Wittgenstein’s Mistress (1988) and Cormac McCarthy’s The Road (2006). Shifting the focus from the very event of catastrophe to the notion of survival through memory and storytelling, both novels problematize the strained relationship between language and reality in an increasingly diminished and dehumanized world. My aim is to investigate the limits of language as well as its capacity to withstand the chaos, loss, trauma, and death that follow the apocalypse. The issues to be considered include the influence of external experience on forms of communication, the role of central metaphors (the archive and the museum in Markson’s novel; cinders and the road in McCarthy’s) and their relation to the form of both novels, as well as the word’s (in)capacity to preserve human values and hopes. Both novels will be discussed as deconstructionist projects in which language becomes a habitat at once impossible and life-preserving: in Wittgenstein’s Mistress it plays the role of both home and prison, whereas in The Road it functions as messianic discourse which simultaneously carries, propels and extinguishes the human hope for a transcendental reality beyond the post-apocalyptic emptiness and doubt.

Download Full-text

The Road More Travelled: The Differential Effects of Spatial Experience in Young and Elderly Participants

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18020709 ◽

2021 ◽

Vol 18 (2) ◽

pp. 709

Author(s):

Antonella Lopez ◽

Alessandro Germani ◽

Luigi Tinella ◽

Alessandro Oronzo Caffò ◽

Albert Postma ◽

...

Keyword(s):

Mental Representations ◽

Spatial Relations ◽

The Elderly ◽

The Road ◽

Socio Demographic Factors ◽

Effects Of Aging ◽

Coordinate Spatial Relations ◽

Categorical Spatial Relations ◽

The Relationship

Our spatial mental representations allow us to give refined descriptions of the environment in terms of the relative locations and distances between objects and landmarks. In this study, we investigated the effects of familiarity with the everyday environment, in terms of frequency of exploration and mode of transportation, on categorical and coordinate spatial relations, on young and elderly participants, controlling for socio-demographic factors. Participants were tested with a general anamnesis, a neuropsychological assessment, measures of explorations and the Landmark Positioning on a Map task. The results showed: (a) a modest difference in performance with categorical spatial relations; (b) a larger difference in coordinate spatial relations; (c) a significant moderating effect of age on the relationship between familiarity and spatial relations, with a stronger relation among the elderly than the young. Ceteris paribus, the role of direct experience with exploring their hometown on spatial mental representations appeared to be more important in the elderly than in the young. This advantage appears to make the elderly wiser and likely protects them from the detrimental effects of aging on spatial mental representations.

Download Full-text

Event-Based Prospective Memory Deficit in Children with ADHD: Underlying Cognitive Factors and Association with Symptoms

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18115849 ◽

2021 ◽

Vol 18 (11) ◽

pp. 5849

Author(s):

Floriana Costanzo ◽

Elisa Fucà ◽

Deny Menghini ◽

Antonella Rita Circelli ◽

Giovanni Augusto Carlesimo ◽

...

Keyword(s):

Prospective Memory ◽

Positive Influence ◽

Attentional Focus ◽

Adhd Group ◽

Typically Developing ◽

Children With Adhd ◽

The Road ◽

Hyperactivity Disorder ◽

Event Based

Event-based prospective memory (PM) was investigated in children with Attention deficit/hyperactivity disorder (ADHD), using a novel experimental procedure to evaluate the role of working memory (WM) load, attentional focus, and reward sensitivity. The study included 24 children with ADHD and 23 typically-developing controls. The experimental paradigm comprised one baseline condition (BC), only including an ongoing task, and four PM conditions, varying for targets: 1 Target (1T), 4 Targets (4T), Unfocal (UN), and Reward (RE). Children with ADHD were slower than controls on all PM tasks and less accurate on both ongoing and PM tasks on the 4T and UN conditions. Within the ADHD group, the accuracy in the RE condition did not differ from BC. A significant relationship between ADHD-related symptoms and reduced accuracy/higher speed in PM conditions (PM and ongoing trials), but not in BC, was detected. Our data provide insight on the adverse role of WM load and attentional focus and the positive influence of reward in the PM performance of children with ADHD. Moreover, the relation between PM and ADHD symptoms paves the road for PM as a promising neuropsychological marker for ADHD diagnosis and intervention.

Download Full-text

Politics, industry, and tourism: The conceptual construction of the blue highway

The Journal of Transport History ◽

10.1177/0022526620979506 ◽

2020 ◽

pp. 002252662097950

Author(s):

Fredrik Bertilsson

Keyword(s):

Road Network ◽

Power Plants ◽

Community Building ◽

Atlantic Coast ◽

Political Agenda ◽

The Road ◽

Conceptual Construction ◽

On The Road ◽

Post War

This article contributes to the research on the expansion of the Swedish post-war road network by illuminating the role of tourism in addition to political and industrial agendas. Specifically, it examines the “conceptual construction” of the Blue Highway, which currently stretches from the Atlantic Coast of Norway, traverses through Sweden and Finland, and enters into Russia. The focus is on Swedish governmental reports and national press between the 1950s and the 1970s. The article identifies three overlapping meanings attached to the Blue Highway: a political agenda of improving the relationships between the Nordic countries, industrial interests, and tourism. Political ambitions of Nordic community building were clearly pronounced at the onset of the project. Industrial actors depended on the road for the building of power plants and dams. The road became gradually more connected with the view of tourism as the motor of regional development.

Download Full-text