Preparation of ordered macroporous cinchonine molecularly imprinted polymers and comparative study of their structure and binding properties with traditional bulk molecularly imprinted polymers

2015 ◽  
Vol 64 (11) ◽  
pp. 1594-1599 ◽  
Author(s):  
Qin Liu ◽  
Yonggang Feng ◽  
Shaomei Huang ◽  
Quanzhou Wu ◽  
Jianfeng He
Keyword(s):  
Comparative Study ◽  
Molecularly Imprinted Polymers ◽  
Binding Properties ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Ordered Macroporous

Study of Chromatographic Properties of Catecholamines and their Acidic Metabolites Using Novel Molecularly Imprinted Polymers as Stationary Phases

2021 ◽  
Vol 903 ◽  
pp. 15-21
Author(s):  
Antons Podjava ◽  
Artūrs Šilaks
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Binding Sites ◽  
Stationary Phases ◽  
Adrenal Tumors ◽  
Binding Properties ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Simultaneous Extraction ◽  
Synthetic Procedure ◽  
Molecularly Imprinted Sorbents

Quantitative analysis of catecholamines and their acidic metabolites can provide vital information for diagnosis and treatment of various diseases (such as adrenal tumors). However, complicated purification protocols are usually required to isolate the analytes. Molecularly imprinted polymers (MIPs) have attracted considerable attention as a method of selectively separating desired compounds from their matrix. Therefore, we propose a synthetic procedure for new molecularly imprinted sorbents that possess selective binding sites for both catecholamines and their acidic metabolites. The new polymer utilizes non-covalent and semi-covalent imprinting methods. The binding properties of MIPs were evaluated using chromatographic experiments. The results suggest that the MIPs bind with catecholamines much more selectively than with their acidic metabolites. Therefore, increasing sorption selectivity of the acids would make it possible to perform simultaneous extraction of both compound groups.

Molecularly Imprinted Polymer for Preparation and Adsorption of Phenylalanine

2011 ◽  
Vol 306-307 ◽  
pp. 638-641 ◽  
Author(s):  
Fu Guang Lu ◽  
Yu Lei Xi ◽  
Zhen Lv ◽  
Lu Lu Fan ◽  
Hua Min Qiu ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Binding Sites ◽  
Template Molecule ◽  
Binding Properties ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Molecular Imprinting Technology ◽  
Particle Size And Morphology ◽  
Size And Morphology ◽  
Polymerization Conditions

Molecular imprinting technology was employed to produce one kind of Phenylalanine ( Phe) molecularly imprinted polymers (MIP)by precipitation polymerization using Phe, anhydrous alcohol, acrylamide, ethylene glycol dimethacrylate, and azobisisobutyronitrile as template, porogen, functional monomer, cross-linker and initiator respectively. In this study, the polymerization conditions were optimized. The template on particle size and morphology of polymers were investigated in detail by scanning electron microscopy (SEM) and adsorption isotherm determination. The binding properties of Phe on imprinted polymers were evaluated in water by equilibrium rebinding experiments, and the maximum number of adsorption was 0.60 mmol/g. It is indicated that the existence of binding sites in imprinted polymers was proved and the binding sites showed good specific and selective capability to the template molecule Phe. So the polymers would be used to separate Phe from medicine and food.

Sythesis of Molecularly Imprinted Polymers for the Binding and Recognition of Nonylphenol

2013 ◽  
Vol 641-642 ◽  
pp. 55-59 ◽  
Author(s):  
Yan Jie Bi ◽  
Wen Yan Li ◽  
Chen Yuan ◽  
Bin Song Wang
Keyword(s):  
Molecularly Imprinted Polymers ◽  
High Selectivity ◽  
Sol Gel ◽  
Template Molecule ◽  
Binding Properties ◽  
Adsorption Selectivity ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Selective Enrichment ◽  
Sol Gel Process

In this paper, molecularly imprinted polymers with high selectivity for nonylphenol (NP) were synthesized by sol-gel process using 4-vinylpyridine (4-Vpy) as functional monomer, ethyleneglycol dimethacrylate as crosslinker (EGDMA), azobisisobutyronitrile (AIBN) as initiator, NP as template molecules. The performance of imprinted material was evaluated by adsorption kinetic, adsorption isotherm and adsorption selectivity. The results indicated that this material had not only binding properties but also high selectivity to the template molecule, which had good application prospects in the selective enrichment and separation of NP for pretreatment and analysis of complex environmental samples.

Sign in / Sign up

Export Citation Format

Share Document