Blood protein adsorption onto macroporous semi-interpenetrating polymer networks (IPNs) of poly(ethylene glycol) (PEG) and poly(2-hydroxyethyl methacrylate) (PHEMA) and assessment ofin vitro blood compatibility

2006 ◽  
Vol 56 (2) ◽  
pp. 231-244 ◽  
Author(s):  
Anil K Bajpai
Keyword(s):  
Ethylene Glycol ◽  
Protein Adsorption ◽  
Blood Compatibility ◽  
Polymer Networks ◽  
Interpenetrating Polymer Networks ◽  
Blood Protein ◽  
Hydroxyethyl Methacrylate ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Semi-interpenetrating polymer networks composed of silk fibroin and poly(ethylene glycol) for wound dressing

2008 ◽  
Vol 3 (3) ◽  
pp. 034115 ◽  
Author(s):  
HaeYong Kweon ◽  
Joo-hong Yeo ◽  
Kwang-gill Lee ◽  
Hyun Chul Lee ◽  
Hee Sam Na ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Silk Fibroin ◽  
Wound Dressing ◽  
Polymer Networks ◽  
Interpenetrating Polymer Networks ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Development of semi- and grafted interpenetrating polymer networks based on poly(ethylene glycol) diacrylate and collagen

2014 ◽  
Vol 12 (3) ◽  
pp. 183-192 ◽  
Author(s):  
Marta Madaghiele ◽  
Francesco Marotta ◽  
Christian Demitri ◽  
Francesco Montagna ◽  
Alfonso Maffezzoli ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Polymer Networks ◽  
Interpenetrating Polymer Networks ◽  
Poly Ethylene Glycol ◽  
Glycol Diacrylate ◽  
Poly Ethylene

scholarly journals Semi-interpenetrating polymer networks of chitosan and poly(ethylene glycol)

2008 ◽  
Vol 62 (6) ◽  
pp. 345-351 ◽  
Author(s):  
Nedeljko Milosavljevic ◽  
Melina Kalagasidis-Krusic ◽  
Jovanka Filipovic
Keyword(s):  
Mechanical Properties ◽  
Ethylene Glycol ◽  
Pore Size ◽  
Biomedical Application ◽  
Polymer Networks ◽  
Crosslinking Agent ◽  
Interpenetrating Polymer Networks ◽  
Swelling Kinetics ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Chitosan is a natural polycationic polymer that possesses useful properties such as bioactivity, biocompatibility, non-toxicity and non-antigenicity. On the other hand, its mechanical properties are not good for some biomedical application. They may be improved by preparing semi-interpenetrating polymer networks (semi-IPNs), when the hydrogel network is prepared in the presence of a previously made polymer such as poly(ethylene glycol). This paper deals with synthesis and characterization of the semi-interpenetrating polymer networks of chitosan and poly(ethylene glycol) with different Ch/PEG ratio and crosslinking degree. The degree of deacetylation of chitosan was determined by potentiometric titration, titration and elemental analysis. The semi-IPNs were characterized by swelling kinetics, mechanical properties and thermal analysis. It was found that PEG content and crosslinking agent concentration significantly influence the swelling behaviour of semi-IPNs. Water uptake was higher for lower crosslinking agent concentrations and PEG contents, up to PEG/Ch = 0,75. Better mechanical strength of semi-IPNs was obtained for higher PEG content and crosslinking agent concentration. SEM analysis confirmed the porous structure of semi-IPNs. Increasing the degree of crosslinking and PEG content up to PEG/Ch = 0,75, the pore size decreased. Based on the pore size, the investigated semi-IPNs can be regarded as macroporous. Thermogravimetric analysis showed that thermal stability of the semi-IPNs depends on the degree of crosslinking, as well as on the PEG content.

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