Characterization of a novel bioactive poly[(lactic acid)-co-(glycolic acid)] and collagen hybrid matrix for dermal regeneration

2005 ◽  
Vol 54 (10) ◽  
pp. 1449-1457 ◽  
Author(s):  
Kee Woei Ng ◽  
Jevon Louis ◽  
Barnabas Saey Tuan Ho ◽  
Hosur N Achuth ◽  
Jia Lu ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Glycolic Acid ◽  
Poly Lactic Acid ◽  
Hybrid Matrix ◽  
Dermal Regeneration

Synthesis and characterization of poly(lactic acid-co-glycolic acid) complex microspheres as drug carriers

2016 ◽  
Vol 31 (4) ◽  
pp. 544-552 ◽  
Author(s):  
Fang Wang ◽  
Xiuxiu Liu ◽  
Jian Yuan ◽  
Siqian Yang ◽  
Yueqin Li ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Glycolic Acid ◽  
Drug Carriers ◽  
Synthesis And Characterization ◽  
Poly Lactic Acid ◽  
Acid Complex

scholarly journals Thermal and Mechanical Characterization of Electrospun Blends of Poly(lactic acid) and Poly(glycolic acid)

2006 ◽  
Vol 38 (11) ◽  
pp. 1137-1145 ◽  
Author(s):  
Lisa I Ramdhanie ◽  
Steven R Aubuchon ◽  
Eugene D Boland ◽  
Danielle C Knapp ◽  
Catherine P Barnes ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Glycolic Acid ◽  
Mechanical Characterization ◽  
Poly Lactic Acid

scholarly journals Mechanical Properties and Bioactivity of Poly(Lactic Acid) Composites Containing Poly(Glycolic Acid) Fiber and Hydroxyapatite Particles

Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 249
Author(s):  
Han-Seung Ko ◽  
Sangwoon Lee ◽  
Doyoung Lee ◽  
Jae Young Jho
Keyword(s):  
Mechanical Properties ◽  
Lactic Acid ◽  
Flexural Strength ◽  
Interfacial Adhesion ◽  
Glycolic Acid ◽  
Compact Bone ◽  
Poly Lactic Acid ◽  
Coupling Reactions ◽  
The Poor ◽  
Human Compact Bone

To enhance the mechanical strength and bioactivity of poly(lactic acid) (PLA) to the level that can be used as a material for spinal implants, poly(glycolic acid) (PGA) fibers and hydroxyapatite (HA) were introduced as fillers to PLA composites. To improve the poor interface between HA and PLA, HA was grafted by PLA to form HA-g-PLA through coupling reactions, and mixed with PLA. The size of the HA particles in the PLA matrix was observed to be reduced from several micrometers to sub-micrometer by grafting PLA onto HA. The tensile and flexural strength of PLA/HA-g-PLA composites were increased compared with those of PLA/HA, apparently due to the better dispersion of HA and stronger interfacial adhesion between the HA and PLA matrix. We also examined the effects of the length and frequency of grafted PLA chains on the tensile strength of the composites. By the addition of unidirectionally aligned PGA fibers, the flexural strength of the composites was greatly improved to a level comparable with human compact bone. In the bioactivity tests, the growth of apatite on the surface was fastest and most uniform in the PLA/PGA fiber/HA-g-PLA composite.

Sign in / Sign up

Export Citation Format

Share Document