scholarly journals Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells

2014 ◽  
Vol 2 (3) ◽  
pp. e00238 ◽  
Author(s):  
Dillon K. Walker ◽  
Micah J. Drummond ◽  
Jared M. Dickinson ◽  
Michael S. Borack ◽  
Kristofer Jennings ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Amino Acid ◽  
Muscle Cells ◽  
Amino Acid Transporter ◽  
Mrna Abundance ◽  
Skeletal Muscle Cells ◽  
Acid Transporter ◽  
Dependent Mechanism

Ceramide down‐regulates System A amino acid transport and protein synthesis in rat skeletal muscle cells

2004 ◽  
Vol 19 (3) ◽  
pp. 1-24 ◽  
Author(s):  
Russell Hyde ◽  
Eric Hajduch ◽  
Darren J. Powell ◽  
Peter M. Taylor ◽  
Harinder S. Hundal
Keyword(s):  
Skeletal Muscle ◽  
Protein Synthesis ◽  
Amino Acid ◽  
Amino Acid Transport ◽  
Muscle Cells ◽  
Skeletal Muscle Cells ◽  
Acid Transport ◽  
Rat Skeletal Muscle ◽  
System A

scholarly journals Effects of antibiotic growth promoter and dietary protease on growth performance, apparent ileal digestibility, intestinal morphology, meat quality, and intestinal gene expression in broiler chickens: a comparison

2020 ◽  
Vol 98 (9) ◽  
Author(s):  
Peng Lu ◽  
Janghan Choi ◽  
Chongwu Yang ◽  
Marion Mogire ◽  
Shangxi Liu ◽  
...  
Keyword(s):  
Amino Acid ◽  
Growth Performance ◽  
Meat Quality ◽  
Amino Acid Transporter ◽  
Intestinal Morphology ◽  
Mrna Abundance ◽  
Growth Promoter ◽  
Ctrl Group ◽  
Ileal Digestibility ◽  
Acid Transporter

Abstract This study aimed to evaluate the effects of supplementing broiler diets with a dietary protease on growth performance, digestive function, intestinal morphology, and meat quality as compared with feeding diets with or without an antibiotic growth promoter (AGP). A total of 240 1-day-old male chicks (Cobb 500, 48.3 ± 3.3 g) were distributed to three treatments with eight replicates (10 birds per replicate). Three treatments were: 1) corn–soybean meal basal diets (CTRL), 2) basal diets with 0.003% avilamycin (AB), and 3) basal diets with 0.0125% protease (PRT). The diets were provided as mash form, and birds were fed ad libitum during the whole experimental period. On day 45, birds were euthanized, and tissue and digesta samples were collected. On day 46, the remaining birds were processed in a commercial slaughterhouse, and breast muscle samples were collected. Despite a trend for a decreased feed conversion ratio (FCR) in the AB group during the whole phase (P = 0.071), no significant differences in growth performance parameters and relative weights of organs were observed (P > 0.05) among the groups. The AB and PRT groups showed significantly greater apparent ileal digestibility of amino acids (AA) compared with the CTRL group (P < 0.05). The PRT group significantly improved the morphology of duodenum and jejunum (P < 0.05). No differences were detected for meat quality, white striping, and woody breast among the groups (P > 0.05). For the gene expressions, the AB group showed a greater level of B0-system neutral amino acid co-transporter 1 and excitatory amino acid transporter 1 mRNA abundance compared with PRT group, while a significantly lesser level of cationic amino acid transporter 1 mRNA abundance was observed in the AB group compared with CTRL group (P < 0.05). The PRT group had a lesser level of peptide transporter 1 mRNA abundance in the jejunum than the CTRL group (P < 0.05). The highest mRNA abundances of zonula occludens-1 and cadherin 1 were observed in the CTRL group (P < 0.05). In conclusion, supplementation of avilamycin tended to reduce FCR and significantly improved AA utilization, and supplementation of dietary protease significantly enhanced intestinal morphology and AA utilization in broilers. In that respect, exogenous protease use appears to be an interesting tool to be considered in AGP reduction strategies.

Glucose and amino acid metabolism in an established line of skeletal muscle cells

1978 ◽  
Vol 96 (3) ◽  
pp. 309-317 ◽  
Author(s):  
William M. Pardridge ◽  
Mayer B. Davidson ◽  
Delia Casanello-Ertl
Keyword(s):  
Skeletal Muscle ◽  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Muscle Cells ◽  
Skeletal Muscle Cells ◽  
Established Line

Energy metabolism profile of the effects of amino acid treatment on skeletal muscle cells: Leucine inhibits glycolysis of myotubes

Nutrition ◽  
2020 ◽  
Vol 77 ◽  
pp. 110794 ◽  
Author(s):  
Reiko Suzuki ◽  
Yoriko Sato ◽  
Kodwo Amuzuah Obeng ◽  
Daisuke Suzuki ◽  
Yusuke Komiya ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Amino Acid ◽  
Energy Metabolism ◽  
Acid Treatment ◽  
Muscle Cells ◽  
Skeletal Muscle Cells
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