Patient‐Level Medication Regimen Complexity in an Adolescent and Adult Population with Autism Spectrum Disorders

2019 ◽  
Vol 39 (6) ◽  
pp. 636-644 ◽  
Author(s):  
Debra J. Barnette ◽  
Christopher Hanks ◽  
Weiyi Li ◽  
Kyle Porter
2016 ◽  
Vol 51 (2) ◽  
pp. 111-117 ◽  
Author(s):  
Alicia Yeh ◽  
Bijal Shah-Manek ◽  
Kajua B. Lor

Background: From 2009 to 2012, 51.8% of American adults with diabetes had a hemoglobin A1C (A1C) >7.0%. The complexity of antidiabetic medication regimens may have an impact on glycemic control. Objective: The primary objective was to test the hypothesis that higher diabetes-specific medication regimen complexity index (MRCI) was associated with lower attainment of A1C goal <7.0% in an underserved, predominantly Hispanic population of adults with type 2 diabetes. Secondary analyses included less stringent A1C goals of <8.0% and <9.0% and overall patient-level MRCI. Methods: This study was a retrospective, observational, cross-sectional study of individuals with type 2 diabetes from January 2011 to January 2016. Data was obtained from the electronic medical record and MRCI was calculated using the 65-item validated Microsoft Access Version 1.0 medication regimen complexity electronic data capture tool. Logistic regression was used to compute unadjusted and adjusted odds ratios. Results: A total of 368 patients were included in the analysis. High diabetes-specific MRCI was associated with lower attainment of A1C goal <7.0% (adjusted OR = 0.09; 95% CI = 0.04-0.18) controlling for age, gender, ethnicity, insurance, body mass index, smoking status, hypertension, and hyperlipidemia. Similar results were obtained for the less stringent A1C goals. However, results for overall patient-level MRCI were mixed. Conclusions: Higher diabetes-specific medication regimen complexity was associated with poorer glycemic control. Simplifying antidiabetic medication regimens, especially where the treatment guidelines give no preference, could be a step toward achieving treatment goals.


2014 ◽  
Vol 36 (11) ◽  
pp. 1538-1546.e1 ◽  
Author(s):  
Sunny A. Linnebur ◽  
Joseph P. Vande Griend ◽  
Kelli R. Metz ◽  
Patrick W. Hosokawa ◽  
Jan D. Hirsch ◽  
...  

2013 ◽  
Vol 35 (4) ◽  
pp. 385-398.e1 ◽  
Author(s):  
Anne M. Libby ◽  
Douglas N. Fish ◽  
Patrick W. Hosokawa ◽  
Sunny A. Linnebur ◽  
Kelli R. Metz ◽  
...  

2019 ◽  
Vol 4 (1) ◽  
pp. e0401180
Author(s):  
Olena Khaustova

Taking into account the prevalence of autism spectrum disorders (ASD) among adults, there is not enough data on the prevalence of ASD among persons undergoing in-patient psychiatric treatment. The purpose of this review is to conduct a systematic review of the literature on the prevalence of autistic spectrum disorders among adult psychiatric inpatients. The criteria for incorporating the articles included: a) the study of the prevalence of autism spectrum disorders; b) research in the population of adult psychiatric inpatient institutions. The review of the articles was carried out in the following electronic databases: PubMed, Medline, CINAHL, PsycINFO and EMBASE. Also, to expand the volume of data, the consultations of specialists in this field were used. As a result of the search, four studies were identified that met the criteria for inclusion in different psychiatric inpatient settings, including private and public. There were significant differences in methodological approaches, including screening tests, diagnostic tools, used diagnostic criteria. Estimates of the prevalence of ASD among the adult population in the psychiatric hospital ranged from 1.7 to 9.6%. From currently available data from a number of studies, it has been found that the prevalence of ASD increases in inpatient psychiatric conditions relative to the general population. There is a need for further research among this group of patients to expand the evidence base, as well as to develop effective strategies for identifying patients with a high probability of ASD in psychiatric inpatient settings among the adult population.


2014 ◽  
Vol 48 (9) ◽  
pp. 1129-1137 ◽  
Author(s):  
Kelli R. Metz ◽  
Douglas N. Fish ◽  
Patrick W. Hosokawa ◽  
Jan D. Hirsch ◽  
Anne M. Libby

2016 ◽  
Vol 50 (11) ◽  
pp. 926-934 ◽  
Author(s):  
Brittney M. Bryant ◽  
Anne M. Libby ◽  
Kelli R. Metz ◽  
Robert L. Page ◽  
Amrut V. Ambardekar ◽  
...  

2010 ◽  
Vol 20 (2) ◽  
pp. 42-50 ◽  
Author(s):  
Laura W. Plexico ◽  
Julie E. Cleary ◽  
Ashlynn McAlpine ◽  
Allison M. Plumb

This descriptive study evaluates the speech disfluencies of 8 verbal children between 3 and 5 years of age with autism spectrum disorders (ASD). Speech samples were collected for each child during standardized interactions. Percentage and types of disfluencies observed during speech samples are discussed. Although they did not have a clinical diagnosis of stuttering, all of the young children with ASD in this study produced disfluencies. In addition to stuttering-like disfluencies and other typical disfluencies, the children with ASD also produced atypical disfluencies, which usually are not observed in children with typically developing speech or developmental stuttering. (Yairi & Ambrose, 2005).


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