Impact of Central Nervous System Stimulant Medication Use on Growth in Pediatric Populations with Attention‐Deficit/Hyperactivity Disorder: A Review

2018 ◽  
Vol 39 (6) ◽  
pp. 665-676 ◽  
Author(s):  
Kyle Troksa ◽  
Nikolas Kovacich ◽  
Michael Moro ◽  
Benjamin Chavez
Keyword(s):  
Central Nervous System ◽  
Attention Deficit Hyperactivity Disorder ◽  
Nervous System ◽  
Attention Deficit ◽  
Stimulant Medication ◽  
Medication Use ◽  
Hyperactivity Disorder ◽  
Central Nervous System Stimulant ◽  
Pediatric Populations

scholarly journals The Impact of Persistent Irritability on the Medication Treatment of Paediatric Attention Deficit Hyperactivity Disorder

2021 ◽  
Vol 12 ◽  
Author(s):  
Raman Baweja ◽  
Daniel A. Waschbusch ◽  
William E. Pelham ◽  
William E. Pelham ◽  
James G. Waxmonsky
Keyword(s):  
Central Nervous System ◽  
Attention Deficit Hyperactivity Disorder ◽  
Nervous System ◽  
Side Effects ◽  
Attention Deficit ◽  
Medication Use ◽  
Growth Patterns ◽  
Hyperactivity Disorder ◽  
Odd Symptoms ◽  
Cns Stimulants

This study compares the efficacy and tolerability of central nervous system (CNS) stimulants in children with attention deficit hyperactivity disorder (ADHD) with and without prominent irritability (IRR) over the course of 30 months. This is a secondary analysis of a study examining growth patterns in medication naïve children with ADHD subsequently treated with CNS stimulants (predominantly OROS-Methylphenidate, up to 54 mg per day) for 30 months. Participants had to meet full diagnostic criteria for ADHD and been treated with CNS stimulants for under 30 days. Children were classified as IRR if they were rated as pretty much or very much on either of the “often angry” or easily annoyed” items plus “lose temper,” items of the Disruptive Behavior Disorders Rating Scale (DBDRS). Structured ratings of ADHD symptoms, impairment, side effects, and symptoms of oppositional defiant disorder (ODD) were collected every 2–12 weeks for the duration of the study. Medication use was measured by pill count and parent report. The IRR group comprised 28% of all participants. The IRR group had significantly higher levels of ADHD and ODD symptoms, impairment, and side effects ratings at baseline. In the IRR group, ODD symptoms, emotional lability, and impairment significantly decreased for participants with higher medication use. Total side effects increased for non-IRR participants with higher medication use. Emotional side effects decreased for IRR participants with higher medication use. Central nervous system stimulants were a tolerable and efficacious treatment in treatment naïve youth with ADHD with irritability.Clinical Trials Registration: NCT01109849

Stimulant Medication Use by Primary Care Physicians in the Treatment of Attention Deficit Hyperactivity Disorder

PEDIATRICS ◽  
1990 ◽  
Vol 86 (1) ◽  
pp. 95-101
Author(s):  
Mark L. Wolraich ◽  
Scott Lindgren ◽  
Ann Stromquist ◽  
Richard Milich ◽  
Charles Davis ◽  
...  
Keyword(s):  
Primary Care ◽  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Primary Care Physicians ◽  
Stimulant Medication ◽  
Medication Use ◽  
The United States ◽  
Hyperactivity Disorder ◽  
Family Practitioners ◽  
Behavioral Treatments

Treatment of attention deficit hyperactivity disorder (ADHD), one of the most common behavioral disorders in children in the United States, remains controversial because of concern about stimulant medication use. Extending a previous study of pediatricians, the present study surveyed a random national sample of family practitioners and then directly screened 457 patients of 10 pediatricians and family practitioners in two small midwestern cities. Responses to the national survey indicated that stimulant medication remains the main treatment prescribed by primary care physicians for children with ADHD. In the direct patient screening, the prevalence of ADHD diagnoses was 5.3% (pediatricians) and 4.2% (family practitioners) of all elementary-schoolaged children screened. Eighty-eight percent of these children were treated with methyiphenidate. Although medication was considered an effective treatment by the parents of 85% of the children given the medication, efficacy was unrelated to the accuracy of diagnosis. When explicit DSM-III-R criteria were used, only 72% of those assigned a diagnosis of ADHD by the physicians would have received that diagnosis based on a structured psychiatric interview with the parents and only 53% received that diagnosis based on teacher report of symptoms, even when the child was not receiving medication. Although the majority of physicians (in both the surveys and the direct screenings) reported using at least some behavioral treatments with their patients, parents reported infrequent use of nonpharmacologic forms of therapy, such as behavior modification. These data thus indicate a relatively modest rate of stimulant medication use for ADHD, but a serious underuse of systematic behavioral treatments in primary care.

Central nervous system processing of emotions in children with nocturnal enuresis and attention-deficit/hyperactivity disorder

2014 ◽  
Vol 103 (8) ◽  
pp. 868-878 ◽  
Author(s):  
Monika Equit ◽  
Anna Becker ◽  
Diana El Khatib ◽  
Mathias Rubly ◽  
Nicolas Becker ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Attention Deficit Hyperactivity Disorder ◽  
Nervous System ◽  
Attention Deficit ◽  
Nocturnal Enuresis ◽  
Hyperactivity Disorder
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