scholarly journals A silicon-labelled amino acid suitable for late-stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis

2018 ◽  
Vol 110 (3) ◽  
pp. e24069
Author(s):  
Kymberley R. Scroggie ◽  
Lisa J. Alcock ◽  
Maria J. Matos ◽  
Gonçalo J. L. Bernardes ◽  
Michael V. Perkins ◽  
...  
Keyword(s):  
Amino Acid ◽  
Late Stage ◽  
Oxidative Cleavage ◽  
Strecker Synthesis ◽  
Cleavage Reactions

scholarly journals A study on the induction of stereoselectivity in the Strecker synthesis of basic amino acid-derived α-amino nitriles

2012 ◽  
Vol 23 (15-16) ◽  
pp. 1198-1205 ◽  
Author(s):  
Pilar Ventosa-Andrés ◽  
M. Teresa García-López ◽  
Rosario Herranz
Keyword(s):  
Amino Acid ◽  
Basic Amino Acid ◽  
Strecker Synthesis

scholarly journals Synthesis of the Tripeptide Antibiotic Resormycin

Synthesis ◽  
2017 ◽  
Vol 49 (24) ◽  
pp. 5351-5356 ◽  
Author(s):  
Loana Musso ◽  
Rahul Kaduskar ◽  
Andrea Pinto ◽  
Leonardo Scaglioni ◽  
Sabrina Dallavalle
Keyword(s):  
Amino Acid ◽  
Antifungal Activity ◽  
Late Stage ◽  
Biological Evaluation ◽  
Synthetic Approach ◽  
Efficient Synthesis ◽  
Hydroxy Amino Acid ◽  
Streptomyces Platensis ◽  
Hydroxy Amino ◽  
Modular Nature

A short and efficient synthesis of resormycin, a metabolite of Streptomyces platensis MJ953-SF5 with herbicidal and antifungal activity, is described. The key step in our synthetic approach is a late-stage stereospecific dehydration of a β-hydroxy amino acid to install the Z-olefin. Because of the modular nature of the synthesis, access to analogues for biological evaluation is readily available.

Cleavage Reactions of Oxazolin-5-ones Reactions with 4-Substituted-2-aryl-2-oxazolin-5-ones

1978 ◽  
Vol 33 (10) ◽  
pp. 1145-1149 ◽  
Author(s):  
Nazmi Kassab ◽  
Abdul Harhash ◽  
Said Elbahaii
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Alkaline Medium ◽  
Ring Closure ◽  
Ring Cleavage ◽  
Aminobenzoic Acids ◽  
Cleavage Reactions

Abstract The oxazoline ring in 4-arylazo-2-aryl-2-oxazolin-5-ones (1) is converted to triazolyl-carbonyl amino acids 2, 4 and 6 by the nucleophiles glycine, anthranilic and p-aminobenzoic acids, respectively. The arylidene derivatives 3 of 2-triazolyl-2-oxazolin-5-one were obtained. Triazolylbenzoxazinones 5, were obtained by the ring closure of the amino acid 4.Grignard's reagent effected ring cleavage of the oxazolinone ring in 4-cinnamylidene-2-aryl-2-oxazolin-5-ones yielding the carbinols 8, the latter cyclizes either in acidic or alkaline medium to afford either benzotropilidenes or oxazolines, respectively.

Amino acid-assisted ferrite/MOF composite formation for visible-light induced photocatalytic cascade C=C aerobic oxidative cleavage functionalization

2021 ◽  
Vol 516 ◽  
pp. 111949
Author(s):  
Fahad S. Al-Mubaddel ◽  
Meghdad Karimi ◽  
Samira Sadeghi ◽  
Reza Ghahremani Gavinehroudi ◽  
Haleh Mohebali ◽  
...  
Keyword(s):  
Amino Acid ◽  
Visible Light ◽  
Oxidative Cleavage ◽  
Composite Formation

Acidolysis and oxidative cleavage reactions of benzylchromium cations

1975 ◽  
Vol 97 (12) ◽  
pp. 3392-3396 ◽  
Author(s):  
Ronald S. Nohr ◽  
James H. Espenson
Keyword(s):  
Oxidative Cleavage ◽  
Cleavage Reactions

scholarly journals Fusarochromene, a novel tryptophan-derived metabolite from Fusarium sacchari

2021 ◽  
Vol 19 (1) ◽  
pp. 182-187
Author(s):  
James W. Marshall ◽  
Kate M. J. de Mattos-Shipley ◽  
Iman A. Y. Ghannam ◽  
Asifa Munawar ◽  
Jonathan C. Killen ◽  
...  
Keyword(s):  
Amino Acid ◽  
Aromatic Amino Acid ◽  
Oxidative Cleavage ◽  
Fusarium Sacchari ◽  
Amino Acid Tryptophan

Fusarochromene and the fusarochromanone mycotoxins are derived via oxidative cleavage of the aromatic amino acid tryptophan.

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