Preparation and properties of benzophenone chromophoric group branched polymer for self-decontamination

Abstract Background Citric acid (CA) is a universal plant and animal-metabolism intermediate. It is a commodity chemical processed and widely used around the world as an excellent pharmaceutical excipient. Notably, CA is offering assorted significant properties viz. biodegradability, biocompatibility, hydrophilicity, safety, etc. Therefore, CA is broadly employed in many sectors including foodstuffs, beverages, pharmaceuticals, nutraceuticals, and cosmetics as a flavoring agent, sequestering agent, buffering agent, etc. From the beginning, CA is a regular ingredient for cosmetic pH-adjustment and as a metallic ion chelator in antioxidant systems. In addition, it is used to improve the taste of pharmaceuticals such as syrups, solutions, elixirs, etc. Furthermore, free CA is also employed as an acidulant in mild astringent preparations. Main text In essence, it is estimated that the functionality present in CA provides excellent assets in pharmaceutical applications such as cross-linking, release-modifying capacity, interaction with molecules, capping and coating agent, branched polymer nanoconjugates, gas generating agent, etc. Mainly, the center of attention of the review is to deliver an impression of the CA-based pharmaceutical applications. Conclusion In conclusion, CA is reconnoitered for multiple novels pharmaceutical and biomedical/applications including as a green crosslinker, release modifier, monomer/branched polymer, capping and coating agent, novel disintegrant, absorption enhancer, etc. In the future, CA can be utilized as an excellent substitute for pharmaceutical and biomedical applications. Graphical abstract

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Motion of a branched polymer chain in confinement: A Monte Carlo study

The Journal of Chemical Physics ◽

10.1063/1.2337627 ◽

2006 ◽

Vol 125 (10) ◽

pp. 104901 ◽

Cited By ~ 4

Author(s):

Piotr Romiszowski ◽

Andrzej Sikorski

Keyword(s):

Monte Carlo ◽

Polymer Chain ◽

Monte Carlo Study ◽

Branched Polymer

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Synthesis and swelling behavior of amphiphilic comb-like branched polymer (AA-co-CMS)-g-PMMA

Polymers for Advanced Technologies ◽

10.1002/pat.1557 ◽

2009 ◽

Vol 20 (12) ◽

pp. 1195-1198 ◽

Cited By ~ 3

Author(s):

Peng Zhang ◽

Ying Feng ◽

Qian Sang ◽

Xiucai Dong ◽

Rui Zhou ◽

...

Keyword(s):

Swelling Behavior ◽

Branched Polymer

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PEG Branched Polymer for Functionalization of Nanomaterials with Ultralong Blood Circulation

Journal of the American Chemical Society ◽

10.1021/ja809086q ◽

2009 ◽

Vol 131 (13) ◽

pp. 4783-4787 ◽

Cited By ~ 408

Author(s):

Giuseppe Prencipe ◽

Scott M. Tabakman ◽

Kevin Welsher ◽

Zhuang Liu ◽

Andrew P. Goodwin ◽

...

Keyword(s):

Blood Circulation ◽

Branched Polymer

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FTIR Analysis of the Lignin Structure Changes of APMP Treated by Laccase and Laccase / Mediator System

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.734-737.2089 ◽

2013 ◽

Vol 734-737 ◽

pp. 2089-2093

Author(s):

Fan Liu ◽

Yu Liu ◽

Jia Chuan Chen ◽

Zhen Wang

Keyword(s):

Oxidative Degradation ◽

No Oxidation ◽

Side Chain ◽

Content Increase ◽

Hydroxyl Content ◽

Structure Changes ◽

Mediator System ◽

Chromophoric Group ◽

Laccase Mediator System ◽

Lignin Structure

In this Paper the Two-Stage Method of Enzyme-Mild Acidic Hydrolysis was Adopted to Separate Lignin from the APMP and the Modified Pulp Samples.And then Analyze the Lignin Structure Changes of the Modified APMP Lignin by Laccase and LMS(laccase/mediator System). it was Found that no Oxidation Took Place on Carbohydrates in the LMS, and Lignin Cα Hydroxyl Oxidization Produce α Carbonyl and H2O2 Bleaching can also Oxidation of Lignin, make the Conjugate C = α Increase;the Syringyl Structure Hydroxyl Content Increase, the Lignin Structure Macromolecular Side Chain Fracturing; Laccase and LMS Oxidative Degradation Chromophoric Group Unsaturated C = O, which can Improve the Brightness of Pulp and Create Better Conditions for Unbleached Pulp.

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Modeling gel effect in branched polymer systems: Free-radical solution homopolymerization of vinyl acetate

Journal of Applied Polymer Science ◽

10.1002/app.29252 ◽

2009 ◽

Vol 111 (5) ◽

pp. 2171-2185 ◽

Cited By ~ 24

Author(s):

George D. Verros ◽

Dimitris S. Achilias

Keyword(s):

Free Radical ◽

Vinyl Acetate ◽

Branched Polymer ◽

Polymer Systems ◽

Gel Effect ◽

Radical Solution

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SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION AMIKACIN IN PURE AND PHARMACEUTICAL DOSAGE FORM

International Journal of Current Pharmaceutical Research ◽

10.22159/ijcpr.2018v10i1.24703 ◽

2018 ◽

Vol 10 (1) ◽

pp. 38

Author(s):

Surya Teja G. ◽

Gurupadayya B. M. ◽

Venkata Sairam K.

Keyword(s):

Dosage Form ◽

Regression Coefficient ◽

Spectroscopic Method ◽

Chloranilic Acid ◽

Pharmaceutical Dosage Form ◽

Ich Guidelines ◽

Highly Sensitive ◽

Acid Reagent ◽

Chromophoric Group ◽

Charge Transfer Complexation

Objective: The aim of the study was to develop an easy, sensible and rapid method for the estimation of amikacin in both pure and marketed formulation using the spectrophotometric method.Methods: Due to lack of chromophoric group in the amikacin, it was derivatized with 0.1 mmol chloranillic acid reagent. For the estimation of amikacin, Shimadzu UV-1700 model spectrophotometer with UV probe software was used. The method was based simple on charge transfer complexation of the drug with a p-chloranilic acid reagent to give a purple coloured product which was measured at 524 nm against blank solution.Results: The derivatised product of amikacin was detected at a wavelength of 524 nm. Linearity was observed with the concentration range of 20-100 µg/ml with a regression coefficient of 0.9803. Results of all the parameters were within the acceptance criteria with % RSD less than 2.Conclusion: The spectroscopic method was validated as per ICH guidelines and was found to be applicable for routine quantitative analysis of amikacin in marketed formulations also. The results of linearity, precision, accuracy LOD and LOQ were within the specified limits. The method is highly sensitive, robust, reproducible and specific.

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