scholarly journals Clinical characteristics and effectiveness of antiviral agents in hospitalized children with infectious mononucleosis in China: A multicenter retrospective study

2021 ◽  
Vol 5 (3) ◽  
pp. 188-194
Author(s):  
Huili Hu ◽  
Huiling Deng ◽  
Jing Bi ◽  
Yi Xu ◽  
Shuangjie Li ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Infectious Mononucleosis ◽  
Clinical Characteristics ◽  
Antiviral Agents ◽  
Hospitalized Children

scholarly journals Clinical Characteristics of Infectious Mononucleosis: A Retrospective Study

2019 ◽  
Vol 62 (11) ◽  
pp. 642-646
Author(s):  
Keon-Ho Kim ◽  
Hee Jeong Kang ◽  
Song Jae Lee ◽  
Chang Myeon Song ◽  
Yong Bae Ji ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Infectious Mononucleosis ◽  
Clinical Characteristics

scholarly journals Analysis of Incidence and Clinical Characteristics of RSV Infection in Hospitalized Children: A Retrospective Study

2021 ◽  
Vol Volume 14 ◽  
pp. 1525-1531
Author(s):  
Ling Gong ◽  
Chunyan Wu ◽  
Mingjie Lu ◽  
Chengyan Huang ◽  
Yongqian Chen ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Clinical Characteristics ◽  
Hospitalized Children ◽  
Rsv Infection

scholarly journals The Clinical Characteristics and Direct Medical Cost of Influenza in Hospitalized Children: A Five-Year Retrospective Study in Suzhou, China

PLoS ONE ◽  
2012 ◽  
Vol 7 (9) ◽  
pp. e44391 ◽  
Author(s):  
Tao Zhang ◽  
Qiuli Zhu ◽  
Xuelan Zhang ◽  
Yunfang Ding ◽  
Mark Steinhoff ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Direct Medical Cost ◽  
Medical Cost ◽  
Clinical Characteristics ◽  
Hospitalized Children

scholarly journals Development of a scale for early prediction of refractory Mycoplasma pneumoniae pneumonia in hospitalized children

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ying Bi ◽  
Yifan Zhu ◽  
Xiao Ma ◽  
Jiejing Xu ◽  
Yun Guo ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Mycoplasma Pneumoniae ◽  
Assessment Scale ◽  
Prognostic Indicators ◽  
Hospitalized Children ◽  
Early Prediction ◽  
Prognostic Assessment ◽  
Standard Clinical Practice ◽  
Children First ◽  
A Prospective Study

AbstractNow there is no clinical scale for early prediction of refractory Mycoplasma pneumoniae pneumonia (RMPP). The aim of this study is to identify indicators and develop an early predictive scale for RMPP in hospitalized children. First we conducted a retrospective cohort study of children with M. pneumoniae pneumonia admitted to Children’s Hospital of Nanjing Medical University, China in 2016. Children were divided into two groups, according to whether their pneumonia were refractory and the results were used to develop an early predictive scale. Second we conducted a prospective study to validate the predictive scale for RMPP in children in 2018. 618 children were included in the retrospective study, of which 73 with RMPP. Six prognostic indicators were identified and included in the prognostic assessment scale. The sensitivity of the prognostic assessment scale was 74.0% (54/73), and the specificity was 88.3% (481/545) in the retrospective study. 944 children were included in the prospective cohort, including 92 with RMPP, the sensitivity of the prognostic assessment scale was 78.3% (72/92) and the specificity was 86.2% (734/852). The prognostic assessment scale for RMPP has high diagnostic accuracy and is suitable for use in standard clinical practice.

scholarly journals Analysis of clinical characteristics of severe pertussis in infants and children: a retrospective study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Caiying Wang ◽  
Huimin Zhang ◽  
Yanlan Zhang ◽  
Lin Xu ◽  
Min Miao ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Clinical Characteristics ◽  
Severe Disease ◽  
Severe Pneumonia ◽  
Infants And Children ◽  
Critically Ill Children ◽  
Young Infants ◽  
Incidence And Mortality ◽  
Increasing Trend ◽  
Medical University

Abstract Background The incidence of pertussis shows an increasing trend in recent years, but some clinicians often lack sufficient understanding of the clinical characteristics and risk factors for severe pertussis, and more effective measures should be taken to reduce the incidence and mortality of pertussis in young infants Methods A retrospective study was conducted, and 184 infants and children with pertussis who had been hospitalized in the Department of Pediatrics of Beijing Ditan Hospital affiliated with Capital Medical University from January 2016 to December 2017 were included. Clinical data of the patients were collected and the clinical characteristics were statistically analyzed Results Among the 184 patients, 41.85% were infants < 3 months of age, and 65.22% of the total patients were not vaccinated against pertussis. There were 22 critically ill children, among whom 4 died, and compared with mild cases, they had a higher proportion of children younger than 3 months of age and infants not vaccinated against pertussis (63.64% vs. 38.89% and 100% vs. 60.49%, respectively); a higher proportion of children with severe pneumonia (100% vs. 0%); higher leukocyte count(× 109/L , 35.80 ± 20.53 vs 19.41 ± 8.59); and a higher proportion of children with severe hyperleukocytosis (18.18% vs. 0%, respectively) (P<0.05) Conclusions 1. Infants aged <3 months not vaccinated for pertussis appear more likely to become infected and have more severe disease. 2. Severe pneumonia and hyperleukocytosis are the main mechanisms underlying severe pertussis.

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