scholarly journals A retrospective study of electroencephalography burst suppression in children undergoing general anesthesia

2021 ◽  
Author(s):  
Zhengzheng Gao ◽  
Jianmin Zhang ◽  
Xiaoxue Wang ◽  
Mengnan Yao ◽  
Lan Sun ◽  
...  
Keyword(s):  
Retrospective Study ◽  
General Anesthesia ◽  
Burst Suppression

Actimetry-documented persistent Periodic Limb Movements during EEG-confirmed deep General Anesthesia: a case report.

2019 ◽  
Author(s):  
Friedrich Lersch ◽  
Pascal Jerney ◽  
Heiko Kaiser ◽  
Cédric Willi ◽  
Katharina Steck ◽  
...  
Keyword(s):  
Case Report ◽  
Motor Activity ◽  
General Anesthesia ◽  
Burst Suppression ◽  
Periodic Limb Movements ◽  
Deep Sclerectomy ◽  
Limb Movements ◽  
Periodic Leg Movements ◽  
Increase Motor Activity ◽  
Leg Movements

Motor activity during general anesthesia (GA) without curarization is often interpreted as reflecting insufficient analgosedation. Here we present the case of an octogenarian scheduled for deep sclerectomy receiving opioid-sparing electroencephalography-(EEG)-guided anesthesia. Periodic Leg Movements (PLM) made their appearance with ongoing surgery while his raw EEG displayed a pattern of deep GA (burst suppression). To the best of our knowledge, this is the first description of actimetry-documented persisting PLM during EEG-monitored GA. Recognizing PLM in the context of GA is of importance for anesthesiologists, as increasing sedation may increase motor activity.

scholarly journals Age-related changes in factors associated with delayed extubation after general anesthesia: a retrospective study

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Naoya Kobayashi ◽  
Toshihiro Wagatsuma ◽  
Takuya Shiga ◽  
Hiroaki Toyama ◽  
Yutaka Ejima ◽  
...  
Keyword(s):  
Retrospective Study ◽  
General Anesthesia ◽  
Factors Associated ◽  
Age Related ◽  
Delayed Extubation ◽  
Age Related Changes

One-Week Postoperative Patency of Lower Extremity In Situ Bypass Graft Comparing Epidural and General Anesthesia: Retrospective Study of 822 Patients

2014 ◽  
Vol 28 (2) ◽  
pp. 295-300 ◽  
Author(s):  
Julie Therese Wiis ◽  
Peter Jensen-Gadegaard ◽  
Ümit Altintas ◽  
Claus Seidelin ◽  
Robertas Martusevicius ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Lower Extremity ◽  
General Anesthesia ◽  
Bypass Graft ◽  
In Situ Bypass

Dynamic Cortical Connectivity during General Anesthesia in Healthy Volunteers

2019 ◽  
Vol 130 (6) ◽  
pp. 870-884 ◽  
Author(s):  
Duan Li ◽  
Phillip E. Vlisides ◽  
Max B. Kelz ◽  
Michael S. Avidan ◽  
George A. Mashour ◽  
...  
Keyword(s):  
Functional Connectivity ◽  
General Anesthesia ◽  
Healthy Volunteers ◽  
Transition Probabilities ◽  
Burst Suppression ◽  
Occurrence Rate ◽  
Connectivity Pattern ◽  
Phase Lag ◽  
Cortical Connectivity ◽  
Isoflurane Anesthesia

Abstract Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Recent studies of anesthetic-induced unconsciousness in healthy volunteers have focused on functional brain connectivity patterns, but the protocols rarely parallel the depth and duration of surgical anesthesia. Furthermore, it is unknown whether there is a single functional connectivity pattern that correlates with general anesthesia for the duration of prolonged anesthetic exposure. Methods The authors analyzed electroencephalographic data in 30 healthy participants who underwent induction of anesthesia with propofol followed by 3 h of isoflurane anesthesia at age-adjusted 1.3 minimum alveolar concentration. Functional connectivity was assessed by frequency-resolved weighted phase lag index between frontal and parietal channels and between prefrontal and frontal channels, which were classified into a discrete set of states through k-means cluster analysis. Temporal dynamics were evaluated by the occurrence rate and dwell time distribution for each state as well as the transition probabilities between states. Results Burst suppression was present, with mean suppression ratio reducing from 44.8 ± 32.3% to 14.0 ± 20.2% (mean ± SD) during isoflurane anesthesia (P < 0.001). Aside from burst suppression, eight connectivity states were classified by optimizing the reproducibility of clustering solutions, with each characterized by distinct properties. The temporal progression of dominant states revealed a successive shifting trajectory from the state associated with alpha frontal-parietal connectivity to those associated with delta and alpha prefrontal-frontal connectivity during induction, which was reversed during emergence. Cortical connectivity was dynamic during maintenance period, and it was more probable to remain in the same state (82.0 ± 8.3%) than to switch to a different state (P < 0.001). However, transitions to other states were structured, i.e., occurred more frequently than expected by chance. Conclusions Anesthesia-induced alterations of functional connectivity are dynamic despite the stable and prolonged administration of isoflurane, in the absence of any noxious stimuli. Changes in connectivity over time will likely yield more information as a marker or mechanism of surgical anesthesia than any single pattern.

General anesthesia safety in progressive leukodystrophies: A retrospective study of patients with Krabbe disease and metachromatic leukodystrophy

2019 ◽  
Vol 29 (10) ◽  
pp. 1053-1059 ◽  
Author(s):  
Nicholas A. Bascou ◽  
Maria C. Marcos ◽  
Maria L. Beltran Quintero ◽  
Mercedes C. Roosen‐Marcos ◽  
Franklyn P. Cladis ◽  
...  
Keyword(s):  
Retrospective Study ◽  
General Anesthesia ◽  
Metachromatic Leukodystrophy ◽  
Krabbe Disease ◽  
Anesthesia Safety

scholarly journals Effects of Female Reproductive Hormone Levels on Inadvertent Intraoperative Hypothermia during Laparoscopic Gynecologic Surgery: A Retrospective Study

Medicina ◽  
2021 ◽  
Vol 57 (11) ◽  
pp. 1255
Author(s):  
Cheol Lee ◽  
SeongNam Park ◽  
ByoungRyun Kim ◽  
Hyeonbin Yim ◽  
Myeongjong Lee ◽  
...  
Keyword(s):  
Retrospective Study ◽  
General Anesthesia ◽  
Odds Ratio ◽  
Reproductive Hormones ◽  
Gynecologic Surgery ◽  
Reproductive Hormone ◽  
Hormone Levels ◽  
Intraoperative Hypothermia ◽  
Hypothermia Group ◽  
Laparoscopic Gynecologic Surgery

Background and Objectives: Female reproductive hormones may affect core body temperature. This study aimed to investigate the effects of female reproductive hormones on inadvertent intraoperative hypothermia in patients who underwent laparoscopic gynecologic surgery under general anesthesia. Materials and Methods: This retrospective study included 660 menstruating and menopausal female patients aged 19–65 years. The patients were divided into two groups according to the occurrence of inadvertent intraoperative hypothermia: non-hypothermia group (N = 472) and hypothermia group (N = 188). After propensity score matching, 312 patients (N = 156 in each group) were analyzed to investigate the association between intraoperative hypothermia and female reproductive hormones. As potential predictors of inadvertent hypothermia, the levels of female reproductive hormones were analyzed using binary logistic regression. Results: The association of estradiol (r = −0.218, p = 0.000) and progesterone (r = −0.235, p = 0.000) levels with inadvertent intraoperative hypothermia was significant but weakly negative before matching; however, it was significant and moderately negative after matching (r = −0.326, p = 0.000 and r = −0.485, p = 0.000, respectively). In a binary logistic analysis, the odds ratio for estradiol was 0.995 (p = 0.014, 0.993 < 95% confidence interval [CI] < 0.998) before matching and 0.993 (p = 0.000, 0.862 < 95% CI < 0.930) after matching, and that for progesterone was 0.895 (p = 0.000, 0.862 < 95% CI < 0.930) before matching and 0.833 (p = 0.014, 0.990 < 95% CI < 0.996) after matching. Conclusions: Estradiol and progesterone levels were associated with inadvertent intraoperative hypothermia. However, the odds ratio for female reproductive hormone levels was close to 1. Therefore, female reproductive hormones may not be a risk factor for hypothermia during gynecologic surgery under general anesthesia. However, a small sample size in this study limits the generalizability of the results.

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