scholarly journals Predictive value of C‐reactive protein and the Pediatric Risk of MortalityIIIScore for occurrence of postoperative ventilator‐associated pneumonia in pediatric patients with congenital heart disease

2019 ◽  
Vol 3 (2) ◽  
pp. 91-95 ◽  
Author(s):  
Yuelin Sun ◽  
Tianxin Zhao ◽  
Dong Li ◽  
Junming Huo ◽  
Lan Hu ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Predictive Value ◽  
Congenital Heart ◽  
Pediatric Patients ◽  
Ventilator Associated Pneumonia ◽  
C Reactive Protein ◽  
Reactive Protein

Hyperuricaemia in congenital heart disease patients

2013 ◽  
Vol 25 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Efrén Martínez-Quintana ◽  
Fayna Rodríguez-González
Keyword(s):  
Body Mass Index ◽  
Congenital Heart Disease ◽  
Uric Acid ◽  
Heart Disease ◽  
Serum Uric Acid ◽  
Congenital Heart ◽  
C Reactive Protein ◽  
Lower Serum ◽  
Reactive Protein ◽  
Low Serum

AbstractIntroductioHyperuricaemia is associated with traditional cardiovascular risk factors such as type 2 diabetes or dyslipidaemia and a higher mortality.MethodsOut of 528 congenital heart disease patients, 329 patients, including 190 male and 139 female patients, in whom uric acid determination was performed, were studied and followed up to determine survival.ResultsMale congenital heart disease patients with high serum uric acid concentrations (>7 mg/dl) showed significantly (p < 0.05) higher body mass index, serum creatinine, total cholesterol, low-density lipoprotein-cholesterol, triglycerides, and C-reactive protein concentrations than those male congenital heart disease patients with lower serum uric acid levels (≤7 mg/dl). Meanwhile, female congenital heart disease patients with higher serum uric acid concentrations (>5.7 mg/dl) were significantly (p < 0.05) younger, more hypoxaemic, more obese, and with higher C-reactive protein and N-terminal-pro-B-type natriuretic peptide levels than those female congenital heart disease patients with lower serum uric acid concentrations (≤5.7 mg/dl). During a median follow-up of 90 months, 16 out of 528 congenital heart disease patients died – 14 patients of cardiac origin and two patients of non-cardiac origin – of whom 10 were hypoxaemic. Kaplan–Meier analysis showed no significant differences in mortality between male and female congenital heart disease patients with high and low serum uric acid level concentrations.ConclusionsHypoxaemia, body mass index, and C-reactive protein concentrations are higher in hyperuricaemic congenital heart disease patients, although no significant differences were seen in mortality between congenital heart disease patients with high and low serum uric acid concentrations.

scholarly journals Prognostic value of C-reactive protein in adults with congenital heart disease

Heart ◽  
2020 ◽  
pp. heartjnl-2020-316813
Author(s):  
Laurie W Geenen ◽  
Vivan J M Baggen ◽  
Annemien E van den Bosch ◽  
Jannet A Eindhoven ◽  
Robert M Kauling ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Prognostic Value ◽  
Congenital Heart ◽  
Cox Regression ◽  
Troponin T ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Risk Of Death ◽  
Hs Crp

BackgroundHigh-sensitivity C reactive protein (hs-CRP) has been associated with outcomes in adult congenital heart disease (ACHD). However, its prognostic value beyond N-terminal pro B type natriuretic peptide (NT-proBNP) or troponin T remains unknown. We studied the temporal evolution of hs-CRP, as well as the relation between hs-CRP and adverse clinical outcomes independent of NT-proBNP and troponin T in patients with ACHD.MethodsIn this prospective cohort study, we enrolled 602 patients with ACHD (2011–2013) who underwent baseline and thereafter annual blood sampling during 4 years. Hs-CRP, hs-troponin T and NT-proBNP were measured. The primary endpoint was composed of death or heart failure (HF). Cox regression and Joint Modelling was used to relate 2log hs-CRP levels with the endpoint, with adjustment for baseline characteristics and (repeated) hs-troponin T and NT-proBNP measurements.ResultsHs-CRP was measured at baseline in 591 patients, median age 33 years, 58% men, 90% New York Heart Association I with an average of 4.3 measurements per patient. Median follow-up was 5.9 (IQR 5.3–6.3) years (99.2% complete) and 69 patients met the endpoint. Higher baseline hs-CRP was independently associated with higher risk of death or HF (HR 1.36, 95% CI 1.19 to 1.55). Hs-CRP increased over time prior to death or HF, and repeated hs-CRP measurements were associated with the endpoint, independent of repeated NT-proBNP and hs-troponin T (HR 1.54, 95% CI 1.24 to 1.98).ConclusionsHs-CRP carries incremental prognostic value for the risk of death or HF, beyond NT-proBNP and hs-troponin T. Hs-CRP increased prior to the occurrence of HF or death, supporting the role of inflammation in the clinical deterioration of patients with ACHD.

C-reactive protein in adults with pulmonary arterial hypertension associated with congenital heart disease and its prognostic value

Heart ◽  
2014 ◽  
Vol 100 (17) ◽  
pp. 1335-1341 ◽  
Author(s):  
Giancarlo Scognamiglio ◽  
Aleksander Kempny ◽  
Laura C Price ◽  
Rafael Alonso-Gonzalez ◽  
Philip Marino ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Prognostic Value ◽  
Congenital Heart ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Pulmonary Arterial

scholarly journals CMR in pediatric patients with congenital heart disease: comparison at 1.5T and at 3.0T

2012 ◽  
Vol 14 (S1) ◽  
Author(s):  
Kim-Lien Nguyen ◽  
Sarah Khan ◽  
John Moriarty ◽  
Kiyarash Mohajer ◽  
Pierangelo Renella ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Pediatric Patients

Heart Rate Recovery Following Exercise Testing in Pediatric Patients with Acyanotic Repaired Congenital Heart Disease

2022 ◽  
Author(s):  
Natalie S. Shwaish ◽  
Lindsey Malloy-Walton ◽  
Keith Feldman ◽  
Kelli M. Teson ◽  
Jessica S. Watson ◽  
...  
Keyword(s):  
Heart Rate ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Exercise Testing ◽  
Congenital Heart ◽  
Pediatric Patients ◽  
Heart Rate Recovery
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