Evaluating the Association between Antidepressant Dose Trajectories and Treatment Augmentation in Pediatric Depression

2021 ◽  
Author(s):  
O' Mareen Spence ◽  
Gloria Reeves ◽  
Susan dosReis
Keyword(s):  
Pediatric Depression

Pharmacotherapy and psychotherapy of pediatric depression

2010 ◽  
Vol 11 (13) ◽  
pp. 2129-2140 ◽  
Author(s):  
Fadi T Maalouf ◽  
David A Brent
Keyword(s):  
Pediatric Depression

Inflammatory Markers and the Pathogenesis of Pediatric Depression and Suicide

2014 ◽  
Vol 75 (11) ◽  
pp. 1242-1253 ◽  
Author(s):  
Jae-Won Kim ◽  
Eva M. Szigethy ◽  
Nadine M. Melhem ◽  
Ester M. Saghafi ◽  
David A. Brent
Keyword(s):  
Inflammatory Markers ◽  
Pediatric Depression

scholarly journals Emotion Regulation Among Adolescents With Pediatric Depression As a Function of Anxiety Comorbidity

2019 ◽  
Vol 10 ◽  
Author(s):  
Roberta Dochnal ◽  
Ágnes Vetró ◽  
Enikö Kiss ◽  
Ildikó Baji ◽  
Eszter Lefkovics ◽  
...  
Keyword(s):  
Emotion Regulation ◽  
Pediatric Depression

Enhanced platelet reactivity in pediatric depression

2015 ◽  
Vol 26 (7) ◽  
pp. 731-735 ◽  
Author(s):  
Mehmet M. Can ◽  
Gamze Guler ◽  
Ekrem Guler ◽  
Olcay Ozveren ◽  
Burak Turan ◽  
...  
Keyword(s):  
Platelet Reactivity ◽  
Pediatric Depression

Relapse and Recurrence in Pediatric Depression

2006 ◽  
Vol 15 (4) ◽  
pp. 1057-1079 ◽  
Author(s):  
Betsy D. Kennard ◽  
Graham J. Emslie ◽  
Taryn L. Mayes ◽  
Jennifer L. Hughes
Keyword(s):  
Pediatric Depression

Assessment of pediatric depression

2014 ◽  
pp. 35-42 ◽  
Author(s):  
Marta Bravo ◽  
Maria Mayoral ◽  
Alejandra Teresa Laorden ◽  
Carmen Moreno
Keyword(s):  
Pediatric Depression

Treatments for Pediatric Depression

2015 ◽  
Author(s):  
Carolina Biernacki ◽  
Prerna Martin ◽  
Pablo H. Goldberg ◽  
Moira A. Rynn
Keyword(s):  
Positive Response ◽  
Behavioral Therapy ◽  
Antidepressant Medication ◽  
Psychosocial Interventions ◽  
Evidence Base ◽  
Treatment Resistant Depression ◽  
Treatment Resistant ◽  
Medication Treatment ◽  
Pediatric Depression ◽  
Resistant Depression

Practice guidelines recommend psychosocial interventions for mild or brief cases of pediatric depression. In moderate to severe cases, medication treatment is recommended, with or without cognitive-behavioral therapy (CBT). Fluoxetine and escitalopram are the only antidepressants approved by the U.S. Food & Drug Administration for acute pediatric depression. Among psychosocial interventions, CBT and interpersonal psychotherapy for adolescents (IPT-A) have the largest evidence base for treatment of depressed youth. Combination treatment with CBT and antidepressant medication is superior to treatment with either modality alone. In treatment-resistant depression, a switch in antidepressant is more likely to yield a positive response when medication is used with CBT. Antidepressants should be used judiciously in youths as higher rates of adverse events have been demonstrated, and data from adult trials cannot be systematically extrapolated to youths. Further studies are needed to assess alternative medication and psychosocial treatments as well as factors predictive of treatment response.

A translational neuroscience framework for the development of socioemotional functioning in health and psychopathology

2013 ◽  
Vol 25 (4pt2) ◽  
pp. 1293-1309 ◽  
Author(s):  
Jillian Lee Wiggins ◽  
Christopher S. Monk
Keyword(s):  
Autism Spectrum ◽  
Socioemotional Development ◽  
Future Directions ◽  
Socioemotional Functioning ◽  
Pediatric Anxiety ◽  
Developmental Neuroscience ◽  
Time Period ◽  
Complex Process ◽  
Pediatric Depression ◽  
Genetic Mechanisms

AbstractThe development of socioemotional functioning is a complex process that occurs over a protracted time period and requires coordinating affective, cognitive, and social faculties. At many points in development, the trajectory of socioemotional development can be deleteriously altered due to a combination of environmental insults and individual vulnerabilities. The result can be psychopathology. However, researchers are just beginning to understand the neural and genetic mechanisms involved in the development of healthy and disordered socioemotional functioning. We propose a translational developmental neuroscience framework to understand the transactional process that results in socioemotional functioning in both healthy and disordered populations. We then apply this framework to healthy socioemotional development, pediatric anxiety, pediatric depression, and autism spectrum disorder, selectively reviewing current literature in light of the framework. Finally, we examine ways that the framework can help to frame future directions of research on socioemotional development and translational implications for intervention.

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