Maternal and neonatal outcomes after exposure to ADHD medication during pregnancy: A systematic review and meta-analysis

2018 ◽  
Vol 28 (3) ◽  
pp. 288-295 ◽  
Author(s):  
Hai-yin Jiang ◽  
Xue Zhang ◽  
Chun-ming Jiang ◽  
Hai-bin Fu
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Neonatal Outcomes ◽  
Adhd Medication ◽  
Maternal And Neonatal Outcomes

scholarly journals Maternal and neonatal outcomes of preeclamptic and normotensive women who underwent cesarean section under spinal Anesthesia: Systematic review and Meta-Analysis

2020 ◽  
Author(s):  
semagn Abate ◽  
Getachew Mergia ◽  
Bivash Basu
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Experimental Studies ◽  
Open Science ◽  
Neonatal Outcomes ◽  
Forest Plot ◽  
Language Restriction ◽  
Maternal And Neonatal Outcomes ◽  
Risk Of Aspiration

Abstract Background: preeclampsia is very challenging for anesthetists due to the heterogeneous clinical spectrum of the disease characterized by hypertension, risk of hypotension, high risk of aspiration, and difficult airway. Therefore, the Meta-Analysis is intended to provide evidence on maternal and neonatal outcomes of preeclamptic parturient. Methods: A comprehensive strategy was conducted in PubMed/Medline, Science Direct, and Cochrane from January 2000 to May 2020 without language restriction. The Heterogeneity among the included studies was checked with forest plot and I2 test. Observational and experimental studies reporting maternal and neonatal outcomes among preeclamptic and normotensive women were included. Results: The Meta-Analysis revealed that pooled incidence of hypotension was reduced by thirty-eight percent in preeclamptic as compared to normotensive parturient, RR=0.62(95% confidence interval (CI): 0.52 to 0.75)Conclusion: The Meta-Analysis revealed that the incidence of hypotension was lower in preeclamptic women when compared to normotensive women. The included studies were low to a very low quality of evidence which entails further randomized controlled trials.Registration: This systematic review and meta-analysis was registered in Open science Network on June 6, 2020, and the registration is available at https://osf.io/jcedt/.

scholarly journals Effects of L-arginine on preeclampsia risks and maternal and neonatal outcomes: A systematic review and meta-analysis

2021 ◽  
Vol 10 (6) ◽  
pp. 241
Author(s):  
RoopaSatyanarayan Basutkar ◽  
Shonitha Sagadevan ◽  
Oorvashree Sri Hari ◽  
MohamedJahangir Sirajudeen ◽  
Gopi Ramalingam
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Neonatal Outcomes ◽  
Maternal And Neonatal Outcomes

scholarly journals Impact of COVID-19 on maternal and neonatal outcomes: a systematic review and meta-analysis

2021 ◽  
Vol 27 (1) ◽  
pp. 36-46 ◽  
Author(s):  
Francesca Di Toro ◽  
Mattheus Gjoka ◽  
Giovanni Di Lorenzo ◽  
Davide De Santo ◽  
Francesco De Seta ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Neonatal Outcomes ◽  
Maternal And Neonatal Outcomes

scholarly journals Maternal and neonatal outcomes associated with biologic exposure before and during pregnancy in women with inflammatory systemic diseases: a systematic review and meta-analysis of observational studies

Rheumatology ◽  
2020 ◽  
Vol 59 (8) ◽  
pp. 1808-1817 ◽  
Author(s):  
Nicole W Tsao ◽  
Nevena Rebic ◽  
Larry D Lynd ◽  
Mary A De Vera
Keyword(s):  
Systematic Review ◽  
Pregnant Women ◽  
Congenital Anomalies ◽  
Observational Studies ◽  
Meta Analysis ◽  
Neonatal Outcomes ◽  
Systemic Diseases ◽  
Adjusted Risk ◽  
Risk Estimates ◽  
Maternal And Neonatal Outcomes

Abstract Objective To determine the association between exposure to biologics in pregnant women with inflammatory systemic diseases and maternal and neonatal outcomes through a meta-analysis of findings from studies identified in a systematic review. Methods We conducted a systematic review of Medline, Embase, and Cochrane Database of Systematic Reviews to identify observational studies assessing the perinatal impacts of biologic in women with inflammatory systemic disease. Findings were meta-analysed across included studies with random-effects models. Crude risk estimates and, where possible, adjusted risk estimates were pooled to determine the impact on results when confounding is addressed. Results Overall, 24 studies were included in the meta-analysis. Meta-analyses of crude risk estimates resulted in pooled odds ratios (OR) for the association of biologic use during pregnancy and the following respective outcomes: congenital anomalies (1.30, 95% CI: 1.02, 1.67), preterm birth (OR 1.61, 95% CI: 1.37, 1.89), and low birth weight (OR 1.68, 95% CI: 1.21, 2.31). However, in pooled analyses of adjusted risk estimates we observed that the association between biologics use during pregnancy in disease-matched exposed and unexposed pregnant women was no longer statistically significant for congenital anomalies (adjusted OR 1.18, 95% CI: 0.88, 1.57). Conclusion Pooled results from studies reporting adjusted risk estimates showed no increased risk of congenital anomalies associated with biologics use, suggesting that increased rates of adverse outcomes may be due to disease activity itself or other confounders.

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