Relevance of frailty to mortality associated with the use of antipsychotics among community-residing older adults with impaired cognition

2018 ◽  
Vol 27 (3) ◽  
pp. 289-298 ◽  
Author(s):  
Colleen J. Maxwell ◽  
Michael A. Campitelli ◽  
David B. Hogan ◽  
Christina Diong ◽  
Peter C. Austin ◽  
...  
Keyword(s):  
Older Adults ◽  
Impaired Cognition

Abstract P011: Hypoglycemia Unawareness is Associated With Impaired Cognition Among Older Adults With Type 1 Diabetes: the Study of Longevity in Diabetes

Circulation ◽  
2019 ◽  
Vol 139 (Suppl_1) ◽  
Author(s):  
Mary E Lacy ◽  
Paola Gilsanz ◽  
Michal Schnaider-Beeri ◽  
Andrew J Karter ◽  
Charles P Quesenberry ◽  
...  
Keyword(s):  
Older Adults ◽  
Type 1 Diabetes ◽  
Hypoglycemia Unawareness ◽  
Impaired Cognition

scholarly journals Use of Bladder Antimuscarinics in Older Adults with Impaired Cognition

2016 ◽  
Vol 65 (2) ◽  
pp. 390-394 ◽  
Author(s):  
Ariel R. Green ◽  
Jodi Segal ◽  
Jing Tian ◽  
Esther Oh ◽  
David L. Roth ◽  
...  
Keyword(s):  
Older Adults ◽  
Impaired Cognition ◽  
Bladder Antimuscarinics

scholarly journals Activity and Cognition in Older Adults With and Without Sleep Apnea

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 220-220
Author(s):  
Nora Mattek ◽  
Jeffrey Kaye ◽  
Zachary Beattie
Keyword(s):  
Older Adults ◽  
Sleep Apnea ◽  
Sleep Duration ◽  
National Study ◽  
Aging Research ◽  
Activity Data ◽  
Increased Risk ◽  
Daily Step Count ◽  
Health Related ◽  
Impaired Cognition

Abstract Many older adults have sleep apnea. It often goes undiagnosed. Sleep apnea is associated with decreased oxygen to the brain, fragmented sleep, shorter sleep duration, impaired cognition, increased risk for dementia, and less clearance of amyloid and tau. Little longitudinal data are available identifying objective measures of sleep apnea over time that may facilitate improved identification of affected persons. One hundred ninety-five participants age 57 or older were enrolled as part of Collaborative Aging Research using Technology (CART) initiative, a national study examining the feasibility of unobtrusive remote sensing and monitoring of cognitive, behavioral, physiological, and health-related activities. Nightly hours of sleep and total daily step count were acquired using a wrist worn device. Sixty (31%) reported having sleep apnea. Those with sleep apnea had a significantly lower MoCA total score than those without (22.9 vs. 24.2, p<0.01) and were more likely to be classified as MCI by MoCA cutoff <23 (49% vs. 24%, p<0.001). Volunteers who live alone were less likely to be diagnosed with sleep apnea (p<0.01). Males were much more likely to report having sleep apnea than females (p<0.0001). Of those with watch-derived activity data, sleep apnea cases had shorter mean sleep duration (7.2 vs. 7.8 hours, p=0.05) and fewer total daily steps than those without sleep apnea (2384 vs 3327, p=0.04). Sleep apnea may be identified by its association with mildly impaired cognition, with shorter sleep duration, and less total daily activity as measured at home via remote continuous monitoring techniques.

Cognitive control constrains memory attributions

2019 ◽  
Vol 42 ◽  
Author(s):  
Colleen M. Kelley ◽  
Larry L. Jacoby
Keyword(s):  
Alzheimer’S Disease ◽  
Older Adults ◽  
Alzheimer's Disease ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitive Control

Abstract Cognitive control constrains retrieval processing and so restricts what comes to mind as input to the attribution system. We review evidence that older adults, patients with Alzheimer's disease, and people with traumatic brain injury exert less cognitive control during retrieval, and so are susceptible to memory misattributions in the form of dramatic levels of false remembering.

Cognitive Load Affects Speech Motor Performance Differently in Older and Younger Adults

2019 ◽  
Vol 62 (5) ◽  
pp. 1258-1277 ◽  
Author(s):  
Megan K. MacPherson
Keyword(s):  
Older Adults ◽  
Cognitive Load ◽  
Motor Performance ◽  
Age Groups ◽  
Incongruent Condition ◽  
Sentence Production ◽  
Movement Duration ◽  
Production Task ◽  
Younger Adults ◽  
Speech Motor

PurposeThe aim of this study was to determine the impact of cognitive load imposed by a speech production task on the speech motor performance of healthy older and younger adults. Response inhibition, selective attention, and working memory were the primary cognitive processes of interest.MethodTwelve healthy older and 12 healthy younger adults produced multiple repetitions of 4 sentences containing an embedded Stroop task in 2 cognitive load conditions: congruent and incongruent. The incongruent condition, which required participants to suppress orthographic information to say the font colors in which color words were written, represented an increase in cognitive load relative to the congruent condition in which word text and font color matched. Kinematic measures of articulatory coordination variability and movement duration as well as a behavioral measure of sentence production accuracy were compared between groups and conditions and across 3 sentence segments (pre-, during-, and post-Stroop).ResultsIncreased cognitive load in the incongruent condition was associated with increased articulatory coordination variability and movement duration, compared to the congruent Stroop condition, for both age groups. Overall, the effect of increased cognitive load was greater for older adults than younger adults and was greatest in the portion of the sentence in which cognitive load was manipulated (during-Stroop), followed by the pre-Stroop segment. Sentence production accuracy was reduced for older adults in the incongruent condition.ConclusionsIncreased cognitive load involving response inhibition, selective attention, and working memory processes within a speech production task disrupted both the stability and timing with which speech was produced by both age groups. Older adults' speech motor performance may have been more affected due to age-related changes in cognitive and motoric functions that result in altered motor cognition.

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