scholarly journals Variable selection for propensity score models when estimating treatment effects on multiple outcomes: a simulation study

2012 ◽  
Vol 22 (1) ◽  
pp. 77-85 ◽  
Author(s):  
Richard Wyss ◽  
Cynthia J. Girman ◽  
Robert J. LoCasale ◽  
M. Alan Brookhart ◽  
Til Stürmer
Keyword(s):  
Propensity Score ◽  
Variable Selection ◽  
Simulation Study ◽  
Treatment Effects ◽  
Multiple Outcomes ◽  
Selection For

scholarly journals Variable Selection for Confounder Control, Flexible Modeling and Collaborative Targeted Minimum Loss-Based Estimation in Causal Inference

2016 ◽  
Vol 12 (1) ◽  
pp. 97-115 ◽  
Author(s):  
Mireille E. Schnitzer ◽  
Judith J. Lok ◽  
Susan Gruber
Keyword(s):  
Propensity Score ◽  
Variable Selection ◽  
Causal Inference ◽  
Simulation Study ◽  
Learning Approaches ◽  
Minimum Loss ◽  
Knowledge Based ◽  
Flexible Modeling ◽  
Selection For ◽  
Highly Correlated

Abstract This paper investigates the appropriateness of the integration of flexible propensity score modeling (nonparametric or machine learning approaches) in semiparametric models for the estimation of a causal quantity, such as the mean outcome under treatment. We begin with an overview of some of the issues involved in knowledge-based and statistical variable selection in causal inference and the potential pitfalls of automated selection based on the fit of the propensity score. Using a simple example, we directly show the consequences of adjusting for pure causes of the exposure when using inverse probability of treatment weighting (IPTW). Such variables are likely to be selected when using a naive approach to model selection for the propensity score. We describe how the method of Collaborative Targeted minimum loss-based estimation (C-TMLE; van der Laan and Gruber, 2010 [27]) capitalizes on the collaborative double robustness property of semiparametric efficient estimators to select covariates for the propensity score based on the error in the conditional outcome model. Finally, we compare several approaches to automated variable selection in low- and high-dimensional settings through a simulation study. From this simulation study, we conclude that using IPTW with flexible prediction for the propensity score can result in inferior estimation, while Targeted minimum loss-based estimation and C-TMLE may benefit from flexible prediction and remain robust to the presence of variables that are highly correlated with treatment. However, in our study, standard influence function-based methods for the variance underestimated the standard errors, resulting in poor coverage under certain data-generating scenarios.

scholarly journals Variable Selection for Propensity Score Models

2006 ◽  
Vol 163 (12) ◽  
pp. 1149-1156 ◽  
Author(s):  
M. Alan Brookhart ◽  
Sebastian Schneeweiss ◽  
Kenneth J. Rothman ◽  
Robert J. Glynn ◽  
Jerry Avorn ◽  
...  
Keyword(s):  
Propensity Score ◽  
Variable Selection ◽  
Selection For

scholarly journals RE: "VARIABLE SELECTION FOR PROPENSITY SCORE MODELS"

2007 ◽  
Vol 166 (2) ◽  
pp. 238-239 ◽  
Author(s):  
I. Shrier ◽  
R. W. Platt ◽  
R. J. Steele
Keyword(s):  
Propensity Score ◽  
Variable Selection ◽  
Selection For

Variable Selection for Propensity Score Estimation via Balancing Covariates

Epidemiology ◽  
2015 ◽  
Vol 26 (2) ◽  
pp. e14-e15 ◽  
Author(s):  
Yeying Zhu ◽  
Maya Schonbach ◽  
Donna L. Coffman ◽  
Jennifer S. Williams
Keyword(s):  
Propensity Score ◽  
Variable Selection ◽  
Selection For

scholarly journals The role of the c -statistic in variable selection for propensity score models

2010 ◽  
Vol 20 (3) ◽  
pp. 317-320 ◽  
Author(s):  
Daniel Westreich ◽  
Stephen R. Cole ◽  
Michele Jonsson Funk ◽  
M. Alan Brookhart ◽  
Til Stürmer
Keyword(s):  
Propensity Score ◽  
Variable Selection ◽  
C Statistic ◽  
Selection For
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