Comparison of recorded medication use in the Medical Birth Registry of Norway with prescribed medicines registered in the Norwegian Prescription Database

2010 ◽  
Vol 20 (3) ◽  
pp. 243-248 ◽  
Author(s):  
Marte Gravseth Espnes ◽  
Tone Bjørge ◽  
Anders Engeland
Keyword(s):  
Medication Use ◽  
Prescription Database ◽  
Birth Registry ◽  
Medical Birth Registry ◽  
Norwegian Prescription Database ◽  
Prescribed Medicines

Validation of Assisted Reproductive Technology in the Medical Birth Registry of Norway Versus the Norwegian Prescription Database

Epidemiology ◽  
2020 ◽  
Vol 31 (5) ◽  
pp. 681-686
Author(s):  
Marte Myhre Reigstad ◽  
Ritsa Storeng ◽  
Kari Furu ◽  
Inger Johanne Bakken ◽  
Anders Engeland ◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Reproductive Technology ◽  
Prescription Database ◽  
Birth Registry ◽  
Medical Birth Registry ◽  
Norwegian Prescription Database

Medication use and association with urinary incontinence in women: Data from the Norwegian Prescription Database and the HUNT study

2018 ◽  
Vol 37 (4) ◽  
pp. 1448-1457 ◽  
Author(s):  
Siri A. Mauseth ◽  
Svetlana Skurtveit ◽  
Eva Skovlund ◽  
Arnulf Langhammer ◽  
Olav Spigset
Keyword(s):  
Urinary Incontinence ◽  
Medication Use ◽  
Prescription Database ◽  
Norwegian Prescription Database ◽  
Hunt Study

scholarly journals Perinatal use of triptans and other drugs for migraine—A nationwide drug utilization study

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0256214
Author(s):  
Fatima Tauqeer ◽  
Mollie Wood ◽  
Sarah Hjorth ◽  
Angela Lupattelli ◽  
Hedvig Nordeng
Keyword(s):  
Information Needs ◽  
Post Partum ◽  
First Trimester ◽  
Population Based ◽  
Migraine Treatment ◽  
Prescription Database ◽  
Birth Registry ◽  
Norwegian Prescription Database ◽  
Utilization Patterns ◽  
Drug Doses

Objective To characterize nationwide utilization patterns of migraine pharmacotherapy before, during, and after pregnancy in women with triptan use. Methods Population-based data were obtained by linking the Medical Birth Registry of Norway and the Norwegian Prescription Database from 2006 to 2017. We included 22,940 pregnancies among 19,669 women with at least one filled triptan prescription, a proxy for migraine, in the year before pregnancy or during pregnancy. The population was classified into four groups: i) continuers; ii) discontinuers; iii) initiators, and vi) post-partum re-initiators. Participant characteristics and prescription fills for other drugs such as analgesics, antinauseants, and preventive drugs among the groups were examined, along with an array of triptan utilization parameters. Results In total, 20.0% of the women were classified as triptan continuers, 54.1% as discontinuers, 8.0% as initiators, and 17.6% as re-initiators. Extended use of triptans (≥15 daily drug doses/month) occurred among 6.9% of the continuers in the first trimester. The top 10% of triptan continuers and initiators accounted for 41% (95% CI: 39.2% - 42.5%) and 33% (95% CI: 30.3% - 35.8%) of the triptan volume, respectively. Triptan continuers and initiators had similar patterns of acute co-medication during pregnancy, but use of preventive drugs was more common among the continuers before, during, and after pregnancy. Conclusion Among women using triptans before and during pregnancy, one in four continued triptan treatment during pregnancy, and extended triptan use was relatively low. Triptan discontinuation during and in the year after pregnancy was common. Use of other acute migraine treatments was higher among both continuers and initiators of triptans. Women using preventive migraine treatment were most commonly triptan continuers and re-initiators after pregnancy. Prescribing to and counseling of women with migraine should be tailored to the condition severity and their information needs to promote optimal migraine management in pregnancy.

scholarly journals Relationship between Maternal and First Year of Life Dispensations of Antibiotics and Antiasthmatics

Antibiotics ◽  
2018 ◽  
Vol 7 (3) ◽  
pp. 84
Author(s):  
Guro Fossum ◽  
Morten Lindbæk ◽  
Svein Gjelstad ◽  
Kari Kværner
Keyword(s):  
Prescription Drugs ◽  
First Year ◽  
Prescription Database ◽  
Birth Registry ◽  
Mother And Child ◽  
Seeking Behavior ◽  
Norwegian Prescription Database ◽  
One Year ◽  
First Year Of Life ◽  
In Pregnancy

Antibiotics are the most frequent prescription drugs used by pregnant women. Our objective was to investigate if the dispensation of antibiotics and antiasthmatics in children less than 1 year of age is associated with prenatal antibiotic exposure. A secondary aim was to explore the incidence of dispensed antibiotics in pregnancy and dispensed antibiotics and antiasthmatics in children. We conducted an observational study using the Peer Academic Detailing study database to select patients eligible for match in the Medical Birth Registry of Norway, a total of 7747 mother-and-child pairs. Details on antibiotic and antiasthmatic pharmacy dispensations were obtained from the Norwegian Prescription Database. One quarter (1948 of 7747) of the mothers in the study had been dispensed antibiotics during pregnancy. In their first year of life, 17% (1289) of the children had had an antibiotic dispensation, 23% (1747) an antiasthmatic dispensation, and 8% (619) of the children had had both. We found a significant association between dispensed antibiotics in pregnancy and dispensed antibiotics to the child during their first year of life; OR = 1.16 (95% CI: 1.002–1.351). The association was stronger when the mothers were dispensed antibiotics at all, independent of the pregnancy period; OR = 1.60 (95% CI: 1.32–1.94). We conclude that the probability for dispensation of antibiotics was increased in children when mothers were dispensed antibiotics, independent of pregnancy. Diagnostic challenges in the very young and parental doctor-seeking behavior may, at least in part, contribute to the association between dispensations in mothers and children below the age of one year.

Data quality of a computerized medical birth registry

1994 ◽  
Vol 19 (4) ◽  
pp. 323-330 ◽  
Author(s):  
J. H. Lu ◽  
F. M. Lin ◽  
W. Y. Shen ◽  
S. J. Chen ◽  
B. T. Hwang ◽  
...  
Keyword(s):  
Data Quality ◽  
Birth Registry ◽  
Medical Birth Registry

scholarly journals Changes in the consumption of antiepileptics and psychotropic medicines after starting low dose naltrexone: A nation-wide register-based controlled before-after study

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Guttorm Raknes ◽  
Lars Småbrekke
Keyword(s):  
Low Dose ◽  
Prescription Database ◽  
Cumulative Number ◽  
Beneficial Effects ◽  
Defined Daily Doses ◽  
Psychotropic Medicines ◽  
Significant Difference ◽  
Norwegian Prescription Database ◽  
One Year ◽  
Low Dose Naltrexone

Abstract In this controlled before-after study based on data from the Norwegian Prescription Database, we examine whether starting off-label use of Low Dose Naltrexone (LDN) is followed by changes in the consumption of psychotropic medicines including antiepileptics. Patients that collected LDN for the first time in 2013 (N = 11247) were included and stratified into three groups based on LDN exposure. We compared differences in means of cumulative number of defined daily doses (DDD) as well as changes in the number of users one year before and one year after starting LDN. There was a dose-response association between increasing LDN exposure and reductions in the number of users of antiepileptics, antipsychotics and antidepressants. There were significant difference-in-differences in DDDs between the groups with the lowest and highest LDN exposure of antipsychotics (1.4 DDD, 95% CI 0.4 to 2.3, p = 0.007), and in number of users of antiepileptics (3.1% points, 95% CI 1.6% to 4.6%, p < 0.001), antipsychotics (2.1% points, 95% CI 1.2% to 3%, p < 0.001), and antidepressants (2.8% points, 95% CI 1.1% to 4.4%, p = 0.001). The findings show an association between the initiation of persistent LDN use and reduced consumption of several psychotropic medicines and antiepileptics. Beneficial effects of LDN in the treatment of psychiatric diseases cannot be ruled out.

scholarly journals Can subjective well-being and body concern in adolescence predict prescribed medication in adulthood? Findings from the Nord-Trøndelag Health Study and the Norwegian Prescription Database

2019 ◽  
Vol 48 (5) ◽  
pp. 559-566
Author(s):  
Adelheid-Charlotte Wærholm ◽  
Eivind Meland ◽  
Reidun L. S. Kjome
Keyword(s):  
Drug Use ◽  
Well Being ◽  
Health Study ◽  
Health Determinants ◽  
Prescription Database ◽  
Adult Health ◽  
Subjective Well Being ◽  
Important Health ◽  
Norwegian Prescription Database ◽  
The Impact

Aim: To examine whether subjective well-being (SW) and body concern among adolescents aged 15–19 years has an impact on adult health, measured by medications dispensed on average 18 years later. Methods: Data collected in the Nord-Trøndelag Health Study (HUNT) was paired with data from the Norwegian Prescription database (NorPD). We investigated the effects of adolescent SW and body concern on total number of medications, on use of anti-infectives (ATC-group J), medication for the musculo-skeletal system (ATC-group M), anxiolytics, hypnotics and sedatives (ATC-groups N05B and N05C), and finally antipsychotics, antidepressants and psychostimulants, agents used for attention-deficit/hyperactivity disorder and nootropics (ATC-groups N05A, N06A and N06B). We used multi-variable models where we entered body dissatisfaction and SW simultaneously in the models in order to adjust for the associations between the predictors, and also adjusted for possible confounders in the models. Results: Both body concern (dieting and dieting desire) and impaired SW predicted drug use 17–18 years after the participants were surveyed in adolescence. The impact was disease specific as body concern was the most influential predictor for drugs used for somatic diseases and complaints, whereas impaired SW was more strongly associated with drug use for mental health diseases and complaints. Conclusions: SW and body concern are important health determinants in the transition between adolescence and adulthood.

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