Human insulin 1992: A significant independent risk factor for sudden hypoglycaemia?

2005 ◽  
Vol 9 (5) ◽  
pp. 174-176 ◽  
Author(s):  
A Teuscher
Keyword(s):  
Risk Factor ◽  
Human Insulin ◽  
Independent Risk Factor ◽  
Significant Independent Risk Factor

scholarly journals Neutrophil to Lymphocyte Ratio in Maternal Blood: A Clue to Suspect Amnionitis

2021 ◽  
Vol 10 (12) ◽  
pp. 2673
Author(s):  
Joon-Hyung Lee ◽  
Chan-Wook Park ◽  
Kyung-Chul Moon ◽  
Joong-Shin Park ◽  
Jong-Kwan Jun
Keyword(s):  
Risk Factor ◽  
Independent Risk Factor ◽  
Rank Correlation ◽  
Maternal Blood ◽  
Spontaneous Preterm Birth ◽  
Spearman’S Rank Correlation ◽  
Group 4 ◽  
Significant Independent Risk Factor ◽  
Study Population ◽  
Group 2

There is no information about whether maternal neutrophil to lymphocyte ratios (NLRs) progressively increase with respect to the progression of acute histologic chorioamnionitis (acute-HCA) and increased maternal NLR is a risk factor for amnionitis, known as advanced acute-HCA, in pregnant women at risk for spontaneous preterm birth (PTB). The objective of the current study is to examine this issue. The study population included 132 singleton PTB (<34 weeks) due to either preterm labor or preterm-PROM with both placental pathology and maternal CBC results within 48 h before delivery. We examined maternal NLRs according to the progression of acute-HCA in extra-placental membranes (EPM) (i.e., group-0, inflammation-free EPM; group-1, inflammation restricted to decidua; group-2, inflammation restricted to the membranous trophoblast of chorion and the decidua; group-3, inflammation in the connective tissue of chorion but not amnion; group-4, amnionitis). Maternal NLRs significantly and progressively increased with the progression of acute-HCA (Spearman’s rank correlation test, γ = 0.363, p = 0.000019). Moreover, the increased maternal NLR (≥7.75) (Odds-ratio 5.56, 95% confidence-interval 1.26-24.62, p < 0.05) was a significant independent risk factor for amnionitis even after the correction for potential confounders. In conclusion, maternal NLRs significantly and progressively increased according to the progression of acute-HCA and the increased maternal NLR (≥7.75) was an independent risk factor for amnionitis in spontaneous PTB. The evaluation of the performance of NLR should clearly require a prospective description of this parameter in a cohort of patients with either threatened PTL or preterm-PROM.

scholarly journals Impact of COPD on COVID-19 prognosis: A nationwide population-based study in South Korea

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sang Chul Lee ◽  
Kang Ju Son ◽  
Chang Hoon Han ◽  
Seon Cheol Park ◽  
Ji Ye Jung
Keyword(s):  
Mechanical Ventilation ◽  
Critical Care ◽  
Risk Factor ◽  
Respiratory Failure ◽  
Independent Risk Factor ◽  
Multivariate Logistic Regression Model ◽  
Significant Independent Risk Factor ◽  
Copd Patients ◽  
All Cause Mortality ◽  
The Impact

AbstractUnderlying chronic respiratory disease may be associated with the severity of coronavirus disease 2019 (COVID-19). This study investigated the impact of chronic obstructive pulmonary disease (COPD) on the risk for respiratory failure and mortality in COVID-19 patients. A nationwide retrospective cohort study was conducted in 4610 patients (≥ 40 years old) infected with COVID-19 between January 20 and May 27, 2020, using data from the Ministry of Health and Welfare and Health Insurance Review and Assessment Service in Korea. The clinical course and various clinical features were compared between COPD and non-COPD patients, and the risks of respiratory failure and all-cause mortality in COPD patients were analyzed using a multivariate logistic regression model. Among 4610 COVID-19 patients, 4469 (96.9%) and 141 (3.1%) were categorized into the non-COPD and COPD groups, respectively. The COPD group had greater proportions of older (≥ 60 years old) (78.0% vs. 45.2%, P < 0.001) and male (52.5% vs. 36.6%, P < 0.001) patients than the non-COPD group. Relatively greater proportions of patients with COPD received intensive critical care (7.1% vs. 3.7%, P = 0.041) and mechanical ventilation (5.7% vs. 2.4%, P = 0.015). Multivariate analyses showed that COPD was not a risk factor for respiratory failure but was a significant independent risk factor for all-cause mortality (OR = 1.80, 95% CI 1.11–2.93) after adjustment for age, sex, and Charlson Comorbidity Index score. Among COVID-19 patients, relatively greater proportions of patients with COPD received mechanical ventilation and intensive critical care. COPD is an independent risk factor for all-cause mortality in COVID-19 patients in Korea.

Tu1546 Sarcopenia: Significant Independent Risk Factor for Poor Survival Following Esophageal Resection

2013 ◽  
Vol 144 (5) ◽  
pp. S-1124
Author(s):  
Aaron S. Rickles ◽  
James C. Iannuzzi ◽  
Dylan R. Nieman ◽  
Michal J. Lada ◽  
Kristin N. Kelly ◽  
...  
Keyword(s):  
Risk Factor ◽  
Independent Risk Factor ◽  
Esophageal Resection ◽  
Poor Survival ◽  
Significant Independent Risk Factor

scholarly journals Dual Effects of Large Spleen Volume After Splenectomy for the Patients With Chronic Liver Disease

2019 ◽  
Vol 104 (9-10) ◽  
pp. 412-422
Author(s):  
Akitoshi Matsuda ◽  
Naohisa Kuriyama ◽  
Shugo Mizuno ◽  
Masanobu Usui ◽  
Hiroyuki Sakurai ◽  
...  
Keyword(s):  
Risk Factor ◽  
Liver Disease ◽  
Liver Function ◽  
Chronic Liver Disease ◽  
Independent Risk Factor ◽  
Splenic Vein ◽  
Chronic Liver ◽  
Spleen Volume ◽  
Significant Independent Risk Factor ◽  
Volume Group

Background After splenectomy in patients with chronic liver disease, a large spleen was reported to be not only a risk factor of portal/splenic vein thrombosis (PSVT), but also a prediction for favorable improvement of liver function. This study aimed to evaluate the risk of PSVT and the improvement of liver function after splenectomy, with special attention to spleen volume (SV). Methods This studied included 50 patients who underwent splenectomy with diagnosed chronic liver disease between January 2005 and December 2017. After evaluation of risk factors for PSVT the cut-off value of SV for predicting PSVT was determined. According to the cut-off value of SV, 50 patients were divided into 2 groups: small-volume group (SVG) and large-volume group (LVG). Postoperative liver functions were compared between the 2 groups. Results Twenty-eight patients developed PSVT. Larger SV was the most significant independent risk factor for PSVT. The cut-off value of SV was 520 mL. Preoperatively, LVG had significantly higher total bilirubin, and MELD (model for end-stage liver disease) score, and had significantly higher rates of pancytopenia than SVG. Postoperatively, compared to SVG, platelet count, choline esterase, and total cholesterol in LVG were significantly increased. Conclusion After splenectomy in the patients with chronic liver disease, large SV is an independent risk factor for PSVT, with a clear benefit in improving liver function, if PSVT is properly diagnosed and managed.

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