First-trimester screening for Down syndrome in France combining fetal nuchal translucency measurement and biochemical markers

2003 ◽  
Vol 23 (10) ◽  
pp. 833-836 ◽  
Author(s):  
Fran�oise Muller ◽  
Clarisse Benattar ◽  
Fran�ois Audibert ◽  
Nathalie Roussel ◽  
Sophie Dreux ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Biochemical Markers ◽  
First Trimester ◽  
Nuchal Translucency ◽  
First Trimester Screening ◽  
Trimester Screening ◽  
Nuchal Translucency Measurement

First-trimester screening for Down syndrome with ductus venosus Doppler studies in addition to nuchal translucency and serum markers

2005 ◽  
Vol 25 (10) ◽  
pp. 901-905 ◽  
Author(s):  
Antoni Borrell ◽  
Anna Gonce ◽  
Josep M. Martinez ◽  
Virginia Borobio ◽  
Albert Fortuny ◽  
...  
Keyword(s):  
Down Syndrome ◽  
First Trimester ◽  
Nuchal Translucency ◽  
Serum Markers ◽  
Ductus Venosus ◽  
Doppler Studies ◽  
First Trimester Screening ◽  
Trimester Screening

scholarly journals Is there still a role for nuchal translucency measurement in the changing paradigm of first trimester screening?

2019 ◽  
Vol 40 (2) ◽  
pp. 197-205 ◽  
Author(s):  
Francesca Bardi ◽  
Pien Bosschieter ◽  
Joke Verheij ◽  
Attie Go ◽  
Monique Haak ◽  
...  
Keyword(s):  
First Trimester ◽  
Nuchal Translucency ◽  
First Trimester Screening ◽  
Trimester Screening ◽  
Nuchal Translucency Measurement

Distribution of Biochemical and Ultrasound Markers Values in the First Trimester Screening Program in Timisoara

2017 ◽  
Vol 68 (7) ◽  
pp. 1636-1639
Author(s):  
Dan Navolan ◽  
Simona Vladareanu ◽  
Ioana Ciohat ◽  
Adrian Carabineanu ◽  
Marius Craina ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Pregnant Women ◽  
Biochemical Markers ◽  
Screening Program ◽  
First Trimester ◽  
Nuchal Translucency ◽  
Ultrasound Measurement ◽  
First Trimester Screening ◽  
Disturbing Factor ◽  
Trimester Screening

The aim of our study was to analyze the distribution of biochemical markers (free-� hCG and PAPP-A) and nuchal translucency (NT) values and their deviation from expected median in our screening program. NT, free-� hCG and PAPP-A values were measured in first trimester sera of 1313 singleton pregnant women. The age (mean �standard deviation) of pregnant women at the time of screening was 28.94�4.95 years and the gestational age was 87.66�4.74 days. The value of NT (median�standard error of mean) was 0.87�0.01 multiple of median corrected (MoMc), of free-b hCG was 1.07�0.02 MoMc and of PAPP-A was 1.06�0.01 MoMc. Since the huge majority of pregnant women carried a healthy fetus it was assumed that the median value of measurements was equal to 1 MoMc and the deviation from median was equal to null. Our results showed that the greatest deviation from the expected median (-0.13 MoMc) was recorded for the NT measurement while the deviation for the free-� hCG and PAPP-A values was 0.07 respectively 0.06. In conclusion the main disturbing factor in calculating the aneuploidy risk was the measurement of NT. A systematic audit of laboratory and ultrasound measurement is necessary.

Sign in / Sign up

Export Citation Format

Share Document