Fetal intracranial hemorrhage: role of fetal MRI

2017 ◽  
Vol 37 (8) ◽  
pp. 827-836 ◽  
Author(s):  
Laura Sanapo ◽  
Matthew T. Whitehead ◽  
Dorothy I. Bulas ◽  
Homa K. Ahmadzia ◽  
Lindsay Pesacreta ◽  
...  
Keyword(s):  
Intracranial Hemorrhage ◽  
Fetal Mri

scholarly journals Coagulopathy and its effect on treatment and mortality in patients with traumatic intracranial hemorrhage

2021 ◽  
Author(s):  
Janne Kinnunen ◽  
Jarno Satopää ◽  
Mika Niemelä ◽  
Jukka Putaala
Keyword(s):  
Intracranial Hemorrhage ◽  
Multivariable Analysis ◽  
International Normalized Ratio ◽  
University Hospital ◽  
Lower Mortality ◽  
Traumatic Intracranial Hemorrhage ◽  
Hemorrhage Volume ◽  
Anticoagulant Medication ◽  
Admission Glasgow Coma Scale

Abstract Background The role of coagulopathy in patients with traumatic brain injury has remained elusive. In the present study, we aim to assess the prevalence of coagulopathy in patients with traumatic intracranial hemorrhage, their clinical features, and the effect of coagulopathy on treatment and mortality. Methods An observational, retrospective single-center cohort of consecutive patients with traumatic intracranial hemorrhage treated at Helsinki University Hospital between 01 January and 31 December 2010. We compared clinical and radiological parameters in patients with and without coagulopathy defined as drug- or disease-induced, i.e., antiplatelet or anticoagulant medication at a therapeutic dose, thrombocytopenia (platelet count < 100 E9/L), international normalized ratio > 1.2, or thromboplastin time < 60%. Primary outcome was 30-day all-cause mortality. Logistic regression analysis allowed to assess for factors associated with coagulopathy and mortality. Results Of our 505 patients (median age 61 years, 65.5% male), 206 (40.8%) had coagulopathy. Compared to non-coagulopathy patients, coagulopathy patients had larger hemorrhage volumes (mean 140.0 mL vs. 98.4 mL, p < 0.001) and higher 30-day mortality (18.9% vs. 9.7%, p = 0.003). In multivariable analysis, older age, lower admission Glasgow Coma Scale score, larger hemorrhage volume, and conservative treatment were independently associated with mortality. Surgical treatment was associated with lower mortality in both patients with and without coagulopathy. Conclusions Coagulopathy was more frequent in patients with traumatic intracranial hemorrhage presenting larger hemorrhage volumes compared to non-coagulopathy patients but was not independently associated with higher 30-day mortality. Hematoma evacuation, in turn, was associated with lower mortality irrespective of coagulopathy.

scholarly journals The Role of Beta-2-Adrenomediated Mechanisms of Injures of Venous Cerebral Blood Flow in Newborn Rats with Intracranial Hemorrhage

2015 ◽  
Vol 15 (2) ◽  
pp. 93-97
Author(s):  
Oksana Valerievna Semyachkina-Glushkovskaya ◽  
◽  
Marya Vasylievna Ulanova ◽  
Arkady Sergeevich Abdurashitov ◽  
Artemii Sergeevich Gekaluk ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Intracranial Hemorrhage ◽  
Newborn Rats ◽  
Beta 2

Fetal MRI of the cardiovascular system: role of steady-state free precession sequences for the evaluation of normal and pathological appearances

2009 ◽  
Vol 114 (6) ◽  
pp. 852-870 ◽  
Author(s):  
L. Manganaro ◽  
S. Savelli ◽  
M. Di Maurizio ◽  
A. Francioso ◽  
F. Fierro ◽  
...  
Keyword(s):  
Steady State ◽  
Cardiovascular System ◽  
Steady State Free Precession ◽  
Fetal Mri ◽  
Free Precession

Calvarial Hemangioendothelioma with Intracranial Hemorrhage

Neurosurgery ◽  
1979 ◽  
Vol 4 (2) ◽  
pp. 178-180 ◽  
Author(s):  
Joseph C. Maroon ◽  
Stephen J. Haines ◽  
John G. Phillips
Keyword(s):  
Intracranial Hemorrhage ◽  
Bone Tumor ◽  
Epidural Hematoma ◽  
Surgical Excision ◽  
Occipital Bone ◽  
Tumor Vascularity ◽  
Wide Surgical Excision ◽  
Life Threatening ◽  
Acute Epidural Hematoma

Abstract A case of a hemangioendothelioma of the occipital bone that presented clinically as an acute epidural hematoma is reported. The literature regarding this rare bone tumor is reviewed. The treatment of choice seems to be wide surgical excision, but life-threatening hemorrhage may occur due to extreme tumor vascularity. The role of radiotherapy remains uncertain.

scholarly journals P23.12: Role of fetal MRI in the clinical practice: a radiologist's point of view

2014 ◽  
Vol 44 (S1) ◽  
pp. 324-324
Author(s):  
L. Ples ◽  
R. Sima ◽  
E. Mihaly ◽  
E. Tarta ◽  
A. Ghergus ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Fetal Mri ◽  
Point Of View

scholarly journals Diagnostic Features of Myelomeningocele: The Role of Ultrafast Fetal MRI

2014 ◽  
Vol 37 (3) ◽  
pp. 219-225 ◽  
Author(s):  
David M. Mirsky ◽  
Erin S. Schwartz ◽  
Deborah M. Zarnow
Keyword(s):  
Imaging Techniques ◽  
Fetal Mri ◽  
Resonance Imaging ◽  
Fetal Magnetic Resonance Imaging ◽  
Diagnostic Features ◽  
Technical Aspects ◽  
Ultrafast Imaging ◽  
Perinatal Management ◽  
Magnetic Resonance Imaging Mri

Fetal magnetic resonance imaging (MRI) is a useful adjunct to ultrasound in the evaluation of neural tube defects. The development of ultrafast imaging techniques has contributed to the increasing clinical use of fetal MRI. This review summarizes the utility, safety and technical aspects of fetal MRI and the role it plays in the evaluation of myelomeningocele. Emphasis is placed on the benefit of fetal MRI as it pertains to presurgical planning and perinatal management.

scholarly journals The Role of the Fetal MRI to Predict the Postnatal Survival in Fetuses with Congenital Diaphragmatic Hernia

2021 ◽  
Author(s):  
Fatma Ceren Sarıoğlu ◽  
Orkun Sarıoğlu ◽  
İnci Türkan Yılmaz ◽  
Bahar Konuralp Atakul ◽  
Deniz Öztekin ◽  
...  
Keyword(s):  
Congenital Diaphragmatic Hernia ◽  
Diaphragmatic Hernia ◽  
Fetal Mri ◽  
Lung Parenchyma ◽  
P Value ◽  
Total Lung Volume ◽  
Ipsilateral Lung ◽  
Liver Herniation ◽  
Magnetic Resonance Imaging Mri

Objective: To assess the role of the magnetic resonance imaging (MRI) to predict the postnatal survival in patients with congenital diaphragmatic hernia (CDH). Method: 25 patients with CDH who had fetal MRI between 2015 and 2020 were enrolled in this retrospective study. Patients were divided into two groups according to the postnatal survival at 30 days of age: alive and dead. The fetal MRI images were assessed to calculate the lung-to-liver signal intensity ratio (LLSIR), and the total lung volume (TLV). In addition, the site of the defect (right or left), accompanying liver herniation (present or absent), detectable-ipsilateral lung parenchyma at the apex (present or absent) were also recorded. MRI images were evaluated by two pediatric radiologists. A p value lesser than 0.05 was considered statistically significant. Results: Among 25 fetuses, 6 were alive and 19 were dead within 30 days after birth. The detectable lung parenchyma had a relationship with the alive group (p = 0.023). Observed-to-expected TLV (p = 0.001) and LLSIR (p = 0.023) were significantly lower in the dead group. Using the cutoff values for the observed-to-expected TLV as 0.27 (a sensitivity of 84%, a specificity of 84%) and for the LLSIR as 2.02 (a sensitivity of 89%, a specificity of 67%) were found as predictors for death. Conclusion: The postnatal survival in CDH may be predicted using the observed-to-expected TLV and LLSIR on the fetal MRI. The presence of the detectable-ipsilateral lung parenchyma at the apex may also be associated with the postnatal survival.

The Role of Platelet Transfusions After Intracranial Hemorrhage in Patients on Antiplatelet Agents: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 141 ◽  
pp. 455-466.e13 ◽  
Author(s):  
Etrusca Brogi ◽  
Davide Corbella ◽  
Federico Coccolini ◽  
Emiliano Gamberini ◽  
Emanuele Russo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Intracranial Hemorrhage ◽  
Meta Analysis ◽  
Antiplatelet Agents ◽  
Platelet Transfusions

Abstract TMP69: Incidence of Intracranial Hemorrhage After Intravenous Thrombolysis in Telestroke

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Nabeel A Herial ◽  
Evan M Fitchett ◽  
Maureen DePrince ◽  
Giuliana Labella ◽  
Kimon Bekelis ◽  
...  
Keyword(s):  
Intracranial Hemorrhage ◽  
Intravenous Thrombolysis ◽  
Study Data ◽  
Hemorrhagic Complication ◽  
Stroke Outcomes ◽  
Intravenous Tissue Plasminogen Activator ◽  
Comprehensive Stroke Center ◽  
Stroke Center ◽  
Iv Tpa

Background: Promoting intravenous tissue plasminogen activator (IV tPA) in treating eligible patients with acute ischemic stroke (AIS) is critical in reducing overall stroke burden. Effective telestroke networks are proven to facilitate higher rates of IV tPA use. Increasing data on stroke outcomes continues to emerge with expansion of telestroke services nationwide. Objective: To estimate the incidence of intracranial hemorrhage (ICH) in AIS patients treated with IV tPA via telestroke evaluation. Methods: In this study, data from a large telestroke network comprising 36 hospitals from 3 States and associated with a university-based health system and comprehensive stroke center was utilized. Data included total of 3198 acute telestroke evaluations performed within the network between January 2014 and June 2016. Distance of spoke hospitals from the hub ranged between 2.5 and 125 miles. All telestroke consultations were done using the remote presence robotic technology. 15% of all telestroke evaluations and 51% of post-IV tPA patients were transferred to the hub. CT imaging was used for identification and ICH as defined mainly in the NINDS trial was used for comparison. Results: Mean age of patients was 67 years (sd=16) and majority were women (n=1759, 55%). Average NIHSS score at presentation was 7. IV tPA was administered to 18% of all telestroke patients. Post IV tPA, any ICH (symptomatic or not) was noted in 8.7% of patients. Petechial hemorrhage was most frequently reported finding. Rate of any ICH in our telestroke population was relatively lower compared to the ECASS II (39%, p<0.001), ECASS III (27%, p<0.001), SITS-MOST (9.6%, p=0.63), ATLANTIS (11.4%, p=0.30), and higher than the NINDS (6.4%, p=0.29). Conclusions: Higher rate of IV tPA use and lower rate of hemorrhagic complication observed in this large study further supports and strengthens the role of telestroke technology and expertise in treatment of AIS.

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