Diagnostic value of ultrasonographic combining biochemical markers for Down syndrome screening in first trimester: a meta-analysis

2015 ◽  
Vol 35 (9) ◽  
pp. 879-887 ◽  
Author(s):  
Yang Liu ◽  
Xingguang Ye ◽  
Na. Zhang ◽  
Baohuan Zhang ◽  
Congcong Guo ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Biochemical Markers ◽  
Meta Analysis ◽  
First Trimester ◽  
Diagnostic Value ◽  
Down Syndrome Screening

Genetic Sonography After First-trimester Down Syndrome Screening

2007 ◽  
Vol 62 (9) ◽  
pp. 571-573
Author(s):  
D A. Krantz ◽  
T W. Hallahan ◽  
V J. Macri ◽  
J N. Macri
Keyword(s):  
Down Syndrome ◽  
First Trimester ◽  
Down Syndrome Screening

Fetal Nasal Bone Assessment in First Trimester Down Syndrome Screening

2008 ◽  
Vol 24 (1) ◽  
pp. 61-66 ◽  
Author(s):  
Recep Has ◽  
Ibrahim Kalelioglu ◽  
Atil Yuksel ◽  
Lemi Ibrahimoglu ◽  
Hayri Ermis ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Nasal Bone ◽  
First Trimester ◽  
Fetal Nasal Bone ◽  
Bone Assessment ◽  
Down Syndrome Screening

scholarly journals The Effect of Down Syndrome Biochemical Markers on Predicting Severity of Preeclampsia

2020 ◽  
Author(s):  
AYSE OZBAN
Keyword(s):  
Down Syndrome ◽  
Pregnant Women ◽  
Biochemical Markers ◽  
First Trimester ◽  
Maternal Serum ◽  
Screening Tests ◽  
Second Trimester ◽  
Study Results ◽  
Second Trimester Screening ◽  
Trimester Screening

Abstract Objective: This study aims to determine whether it is possible to predict preeclampsia by comparing postpartum results and test results of the pregnant women diagnosed with preeclampsia, whose first and/or second trimester screening tests were accessible, and to demonstrate the predictability of severity and week of onset.Background: 204 patients underwent renal transplantation in our center and 84 of them were female. Five of our patients (one of them had two births) gave birth to a total of 6 pregnancies.Method: 135 patients were diagnosed with preeclampsia and their first and/or second trimester screening tests were accessible, and 366 control participants gave birth to a healthy baby between 37-41 weeks after standard follow-up period for pregnancy and their screening tests were also accessible.Results: The study results show that the first trimester maternal serum PAPP-A level is significantly low in preeclamptic pregnant women, and that the second trimester maternal serum AFP and hCG levels are significantly high and uE3 levels are significantly low The results also suggest that the first and second trimester Down syndrome biochemical markers can be used in preeclampsia screening.Conclusion: Among these markers, uE3 is the parameter which affects the possibility of preeclampsia the most. However, the first and second trimester Down syndrome biochemical markers are not effective in predicting the severity and onset week of preeclampsia.

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