Apparent diffusion coefficient measurements of the fetal brain during the third trimester of pregnancy: how reliable are they in clinical practice?

2014 ◽  
Vol 34 (4) ◽  
pp. 357-366 ◽  
Author(s):  
Agnès Sartor ◽  
Owen Arthurs ◽  
Corinne Alberti ◽  
Nadia Belarbi ◽  
Bogdana Tilea ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Clinical Practice ◽  
Apparent Diffusion Coefficient ◽  
Fetal Brain ◽  
Third Trimester ◽  
The Third ◽  
Apparent Diffusion

Regional apparent diffusion coefficient values in 3rd trimester fetal brain

2014 ◽  
Vol 56 (7) ◽  
pp. 561-567 ◽  
Author(s):  
Chen Hoffmann ◽  
Boaz Weisz ◽  
Shlomo Lipitz ◽  
Gal Yaniv ◽  
Eldad Katorza ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Fetal Brain ◽  
Apparent Diffusion Coefficient Values ◽  
Apparent Diffusion

scholarly journals The Influence of Various Cerebral and Extracerebral Pathologies on Apparent Diffusion Coefficient Values in the Fetal Brain

2020 ◽  
Vol 30 (4) ◽  
pp. 477-485
Author(s):  
Nadja Schönberg ◽  
Christian Weisstanner ◽  
Roland Wiest ◽  
Harald M. Bonél ◽  
Eike I. Piechowiak ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Fetal Brain ◽  
Apparent Diffusion Coefficient Values ◽  
Apparent Diffusion

scholarly journals Normative Apparent Diffusion Coefficient Values in the Developing Fetal Brain

2009 ◽  
Vol 30 (9) ◽  
pp. 1799-1803 ◽  
Author(s):  
M.M. Schneider ◽  
J.I. Berman ◽  
F.M. Baumer ◽  
H.C. Glass ◽  
S. Jeng ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Fetal Brain ◽  
Apparent Diffusion Coefficient Values ◽  
Apparent Diffusion

Assessment of Apparent Diffusion Coefficient of Normal Fetal Brain Development from Gestational Age Week 24 Up to Term Age: A Preliminary Study

2014 ◽  
Vol 37 (2) ◽  
pp. 102-107 ◽  
Author(s):  
Rui Han ◽  
Lu Huang ◽  
Ziyan Sun ◽  
Dongyou Zhang ◽  
Xinlin Chen ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
White Matter ◽  
Apparent Diffusion Coefficient ◽  
Brain Development ◽  
Gestational Age ◽  
Fetal Brain ◽  
Adc Value ◽  
Apparent Diffusion ◽  
Fetal Brain Development ◽  
Adc Values

Objectives: This study was designed to investigate the feasibility of apparent diffusion coefficient (ADC) values in evaluating normal fetal brain development from gestational week 24 up to term age. Methods: Diffusion-weighted imaging (DWI) was performed on 40 normal fetuses (with normal results on sonography and normal fetal MRI results), with two b-values of 0 and 600 s/mm2 in the three (x, y, z) orthogonal axes. Ten regions of interest (ROIs) were manually placed symmetrically in the bilateral frontal white matter (FWM), occipital white matter (OWM), thalamus (THAL), basal ganglia (BG), and cerebellar hemispheres (CH). ADC values of the ten ROIs in all subjects were measured by two radiologists independently. One-way ANOVA was used to calculate the differences among the five regions in the fetal brain and linear regression analysis was used to evaluate the correlation between ADC values and gestational age (GA). p < 0.05 was considered significantly different. Results: Mean GA was 31.3 ± 3.9 (range 24-41) weeks. The overall mean ADC values (×10-6 mm2/s) of the fetuses were 1,800 ± 214 (FWM), 1,400 ± 100 (BG), 1,300 ± 126 (THAL), 1,700 ± 133 (OWM) and 1,400 ± 155 (CH), respectively. The ADC value of BG was not significantly different from those of THAL and CH, while the other four ROIs had significant differences with each other. The ADC values of BG, THAL, OWM and CH had strong negative correlations with increasing GA (R were -0.568, -0.716, -0.830 and -0.700, respectively, all p < 0.01), OWM declined fastest with GA, followed by CH and THAL, the slowest being BG. The ADC value of FWM had no significant change with GA (p = 0.366). Conclusions: The measurement of ADC values is feasible to evaluate fetal brain development with high reliability and reproducibility.

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