Unchanged prevalence of Down syndrome in the Netherlands: results from an 11-year nationwide birth cohort

2012 ◽  
Vol 32 (11) ◽  
pp. 1035-1040 ◽  
Author(s):  
Helma B. M. van Gameren-Oosterom ◽  
S. E. Buitendijk ◽  
C. M. Bilardo ◽  
Karin M. van der Pal-de Bruin ◽  
J. P. Van Wouwe ◽  
...  
2011 ◽  
Vol 55 (5) ◽  
pp. 462-473 ◽  
Author(s):  
G. de Graaf ◽  
M. Haveman ◽  
R. Hochstenbach ◽  
J. Engelen ◽  
K. Gerssen-Schoorl ◽  
...  

2020 ◽  
Vol 59 (12) ◽  
pp. 1086-1091
Author(s):  
Kathryn K. Ostermaier ◽  
Amy L. Weaver ◽  
Scott M. Myers ◽  
Ruth E. Stoeckel ◽  
Slavica K. Katusic ◽  
...  

American Academy of Pediatrics (AAP) guidelines for children with Down syndrome (DS) include assessment for celiac disease (CD), although data to support this recommendation have been inconsistent. We determined the incidence of CD among children with DS in a population-based birth cohort of children born from 1976 to 2000 in Olmsted County, Minnesota. Individuals with karyotype-confirmed DS and CD (using diagnosis codes, positive serology, and duodenal biopsies) were identified. The incidence of CD in DS was compared with the published incidence of CD for Olmsted County residents (17.4 [95% confidence interval = 15.2-19.6] per 100 000 person-years). Among 45 individuals with DS from the birth cohort, 3 (6.7%) were identified with positive celiac serology and confirmatory biopsies at ages 9, 12, and 23 years, for an incidence of 325 per 100 000 person-years. Thus, individuals with DS have more than 18 times the incidence rate of CD compared with the general population, supporting the AAP guidelines.


2013 ◽  
Vol 26 (1) ◽  
pp. 45-62 ◽  
Author(s):  
Sanne Groen ◽  
Paul Vermeer

Abstract Religious disaffiliation, a major phenomenon in the Netherlands, is predominantly a generational matter. Each successive birth cohort is less involved in institutional religion than the previous one. Parents do not seem to pass on a lasting religious commitment to their offspring, which might indicate an overall shift in parental values from conformity to autonomy. In this article we use panel data to test the assumption and to compare parenting goals and their effects on the offspring’s church attendance over two generations of parents. Our research question is: To what extent is the intergenerational transmission of religious commitment affected by a change in parental values from an emphasis on conformity to an emphasis on autonomy? Results show that while there is indeed a shift in parental values from conformity to autonomy, this barely affects the offspring’s church attendance — which is determined, rather, by the parents’ church attendance, irrespective of the goals they pursue.


2006 ◽  
Vol 43 (6) ◽  
pp. 710-714 ◽  
Author(s):  
F. J. C. van der Veen ◽  
J. M. van Hagen ◽  
J. Berkhof ◽  
J. P. W. Don Griot

Objective: The Dutch Cleft Palate Association (DCPA) registers all patients with cleft lip or palate and associated congenital anomalies in the Netherlands. The aim of this study was to assess if early registration of cleft patients leads to underreporting of associated congenital anomalies and, if so, whether reregistration is necessary. Methods: The DCPA registration of the birth cohort 1997 to 2001 was compared with the medical files of these cleft patients for prevalence, type, and moment of registration of associated congenital anomalies. To assess possible long-term underregistration, a second birth cohort of 1990 to 1991 was analyzed. Results: The percentage of cleft patients with associated congenital anomalies was 26% in the DCPA database and 33% in the retrospective medical file review. A syndrome, sequence, or association was recognized in 8% of the cleft patients by the DCPA compared with 13% in our medical file review. Of all associated congenital anomalies diagnosed during a follow-up of 12 years, 53% were diagnosed in the first year of life. The cumulative percentage was 59% after 2 years, 62% after 3 years, 80% after 6 years, and 97% after 10 years. Conclusion: Early registration of cleft patients leads to underreporting of other associated anomalies. For a complete registration of associated congenital anomalies in cleft patients, reregistration at a later age is necessary.


2006 ◽  
Vol 26 (8) ◽  
pp. 711-718 ◽  
Author(s):  
P. C. J. I. Schielen ◽  
M. van Leeuwen-Spruijt ◽  
I. Belmouden ◽  
L. H. Elvers ◽  
M. Jonker ◽  
...  

2016 ◽  
Vol 22 (8) ◽  
pp. 736.e9-736.e15 ◽  
Author(s):  
J.G. Wildenbeest ◽  
M.P. van der Schee ◽  
S. Hashimoto ◽  
K.S.M. Benschop ◽  
R.P. Minnaar ◽  
...  

2015 ◽  
Vol 18 (2) ◽  
pp. 179-187 ◽  
Author(s):  
Päivi Merjonen ◽  
Conor V. Dolan ◽  
Meike Bartels ◽  
Dorret I. Boomsma

The aim of the present article was to study the prevalence and the heritability of the initiation of breastfeeding in the Netherlands. The study was carried out in 5,581 participants from the Netherlands Twin Register, and included female twins, their sisters and mothers. All of the participants were born between 1911 and 1991. Breastfeeding was self-reported by the participants, and its prevalence was estimated conditional on birth cohort (born before 1955, 1955–1964, 1965–1974, 1975, or later). To estimate the heritability, we conducted extended twin-family modeling using the SEM package OpenMx in R. Mothers of twins had lower prevalence to initiate breastfeeding and the prevalence of initiation of breastfeeding increased with birth cohort: among mothers of twins 66% in the oldest (pre-1955) to 74% in the youngest (post-1974) and among mothers, who were twins themselves or sisters of twins, 79% in the oldest (pre-1955) to 85% in the youngest (post-1974). When accounting for prevalence differences between mothers of twins and other women, heritability of initiation of breastfeeding was 70%. However, the familial resemblance for sister and mother-daughter pairs was clearly lower than for DZ twin pairs, but as the number of non-twin sisters was relatively low, this observation did not lead to a significant contribution of a special shared twin environment.


1999 ◽  
Vol 45 (6) ◽  
pp. 920-920
Author(s):  
T Vik ◽  
K Borthne ◽  
O. J. Johansen
Keyword(s):  

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