Characterization of fetal cardiac structure and function detected by echocardiography in women with normal pregnancy and gestational diabetes mellitus

2011 ◽  
Vol 31 (5) ◽  
pp. 459-465 ◽  
Author(s):  
Yunyun Ren ◽  
Qiongjie Zhou ◽  
Yingliu Yan ◽  
Chen Chu ◽  
Yonghao Gui ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Normal Pregnancy ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Cardiac Structure And Function ◽  
And Function

scholarly journals Association of Gestational Diabetes Mellitus With Left Ventricular Structure and Function: The CARDIA Study

Diabetes Care ◽  
2016 ◽  
Vol 39 (3) ◽  
pp. 400-407 ◽  
Author(s):  
Duke Appiah ◽  
Pamela J. Schreiner ◽  
Erica P. Gunderson ◽  
Suma H. Konety ◽  
David R. Jacobs ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Left Ventricular ◽  
Structure And Function ◽  
Left Ventricular Structure ◽  
Ventricular Structure ◽  
And Function

scholarly journals History of gestational diabetes mellitus and postpartum maternal retinal microvascular structure and function

2019 ◽  
Vol 36 (6) ◽  
pp. 784-786
Author(s):  
K. H. Yee ◽  
K. H. Tan ◽  
I. M. Aris ◽  
E. L. Lamoureux ◽  
Y. S. Chong ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Structure And Function ◽  
History Of ◽  
And Function

scholarly journals Ultrastructure of Placenta of Gravidas with Gestational Diabetes Mellitus

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Qian Meng ◽  
Li Shao ◽  
Xiucui Luo ◽  
Yingping Mu ◽  
Wen Xu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Morphological Changes ◽  
Basal Membrane ◽  
Normal Pregnancy ◽  
Placental Development ◽  
Terminal Villi ◽  
And Function ◽  
And Control

Objectives. Gestational diabetes mellitus (GDM) leads to an abnormal placental environment which may cause some structural alterations of placenta and affect placental development and function. In this study, the ultrastructural appearances of term placentas from women with GDM and normal pregnancy were meticulously compared.Materials and Methods. The placenta tissues of term birth from 10 women with GDM and 10 women with normal pregnancy were applied with the signed informed consent. The morphology of fetomaternal interface of placenta was examined using light microscopy (LM) and transmission electron microscopy (TEM).Results. On LM, the following morphological changes in villous tissues were found in the GDM placentas when compared with the control placentas: edematous stroma, apparent increase in the number of syncytial knots, and perivillous fibrin deposition. On TEM, the distinct ultrastructural alterations indicating the degeneration of terminal villi were found in the GDM placentas as follows: thickening of the basal membrane (BM) of vasculosyncytial membrane (VSM) and the VSM itself, significantly fewer or even absent syncytiotrophoblastic microvilli, swollen or completely destroyed mitochondria and endoplasmic reticulum, and syncytiotrophoblasts with multiple vacuoles.Conclusion. Ultrastructural differences exist between GDM and control placentas. The differences of placenta ultrastructure are likely responsible for the impairment of placental barrier and function in GDM.

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