First-trimester serum marker distribution in singleton pregnancies conceived with assisted reproduction

2010 ◽  
Vol 30 (4) ◽  
pp. 372-377 ◽  
Author(s):  
M. A. J. Engels ◽  
M. Kooij ◽  
R. Schats ◽  
J. W. R. Twisk ◽  
M. A. Blankenstein ◽  
...  
2009 ◽  
Vol 201 (6) ◽  
pp. S226
Author(s):  
Melanie Engels ◽  
Marjolein Kooij ◽  
Roel Schats ◽  
Jos W. Twisk ◽  
Rien Blankenstein ◽  
...  

2005 ◽  
Vol 20 (9) ◽  
pp. 2623-2627 ◽  
Author(s):  
José Bellver ◽  
Coral Lara ◽  
Sergio R. Soares ◽  
Alberto Ramírez ◽  
Antonio Pellicer ◽  
...  

Med Phoenix ◽  
2017 ◽  
Vol 2 (1) ◽  
pp. 34-37
Author(s):  
Akhilesh Kumar Jha ◽  
Bikranta Rimal ◽  
Tarannum Khatun

Background: Ultrasonography is the reliable and safe way for the evaluation of pregnancy. Heart rate can be detected more confidently from the Ultrasonography. Heart rate is an important parameter for the evaluation of early pregnancy. The purpose of this study was to evaluate the normal heart rate in embryos/fetuses between 6 and 8 weeks of gestation.Method: In our region people are poor and most of them do not know the benefit of regular follow up examination during pregnancy. So most of pregnant women come to our centre at late stage of pregnancy. The number of pregnancy cases is good in our centre but the number of early pregnancy cases coming to regular follow up examination is low. Thus the study was conducted in 51 normal singleton pregnancies undergoing routine ultrasound examination during the first trimester of pregnancy. The duration of study was 6 weeks.Result: Out of 51 singleton pregnancies, 20 cases (39.2%) heart rate were between 131-150 beat per minute and 25 cases (49.0 %) heart rate were between 151-170 beat per minute. However 4 cases (7.8%) were between 110-120 beat per minute and 2 cases (3.9%) were more than 171 beat per minute. There were zero cases above the 180 beat per minute.Conclusion: The result of this study will help to evaluate abnormal and normal fetal heart rate so that early clinical decision whether to continue the pregnancy or terminate it can be taken, as Ultrasonography is only the method used in screening fetal well being in most of the region of our country.Med Phoenix Vol.2(1) July 2017, 34-37


2015 ◽  
Vol 212 (1) ◽  
pp. S142
Author(s):  
Laura L. Jelliffe-Pawlowski ◽  
Rebecca Baer ◽  
Yair Blumenfeld ◽  
Christina Chambers ◽  
Maurice Druzin ◽  
...  

2020 ◽  
Vol 47 (10) ◽  
pp. 749-756
Author(s):  
José A. Sainz ◽  
María R. Torres ◽  
Ignacio Peral ◽  
Reyes Granell ◽  
Manuel Vargas ◽  
...  

<b><i>Introduction:</i></b> Contingent cell-free (cf) DNA screening on the basis of the first-trimester combined test (FCT) results has emerged as a cost-effective strategy for screening of trisomy 21 (T21). <b><i>Objectives:</i></b> To assess performance, patients’ uptake, and cost of contingent cfDNA screening and to compare them with those of the established FCT. <b><i>Methods:</i></b> This is a prospective cohort study including all singleton pregnancies attending to their FCT for screening of T21 at 2 university hospitals in South Spain. When the FCT risk was ≥1:50, there were major fetal malformations, or the nuchal translucency was ≥3.5 mm, women were recommended invasive testing (IT); if the risk was between 1:50 and 1:270, women were recommended cfDNA testing; and for risks bellow 1:270, no further testing was recommended. Detection rate (DR), false-positive rate (FPR), patients’ uptake, and associated costs were evaluated. <b><i>Results:</i></b> We analyzed 10,541 women, including 46 T21 cases. DR of our contingent strategy was 89.1% (41/46) at 1.4% (146/10,541) FPR. Uptake of cfDNA testing was 91.2% (340/373), and overall IT rate was 2.0%. The total cost of our strategy was €1,462,895.7, similar to €1,446,525.7 had cfDNA testing not been available. <b><i>Conclusions:</i></b> Contingent cfDNA screening shows high DR, low IT rate, and high uptake at a similar cost than traditional screening.


2019 ◽  
Vol 134 (4) ◽  
pp. 863-868 ◽  
Author(s):  
Mackenzie N. Naert ◽  
Alberto Muniz Rodriguez ◽  
Hanaa Khadraoui ◽  
Mariam Naqvi ◽  
Nathan S. Fox

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