Prenatal diagnosis of X-linked mental retardation with fragile (X) using fetoscopy and fetal blood sampling

1983 ◽  
Vol 3 (2) ◽  
pp. 131-137 ◽  
Author(s):  
T. Webb ◽  
C. M. Gosden ◽  
C. H. Rodeck ◽  
M. A. Hamill ◽  
P. E. Eason
Keyword(s):  
Mental Retardation ◽  
Prenatal Diagnosis ◽  
Fragile X ◽  
Blood Sampling ◽  
Fetal Blood ◽  
Fetal Blood Sampling

PRENATAL DIAGNOSIS OF ? THALASSEMIA: EXPERIENCE WITH 133 CASES AND THE EFFECT OF FETAL BLOOD SAMPLING ON CHILD DEVELOPMENT

1980 ◽  
Vol 344 (1 Fourth Cooley) ◽  
pp. 165-180 ◽  
Author(s):  
A. Cao ◽  
M. Furbetta ◽  
A. Angius ◽  
A. Ximenes ◽  
G. Angioni ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Child Development ◽  
Blood Sampling ◽  
Fetal Blood ◽  
Fetal Blood Sampling

Prenatal diagnosis of alpha-1-antitrypsin deficiency by fetal blood sampling

1987 ◽  
Vol 7 (2) ◽  
pp. 101-108 ◽  
Author(s):  
G. Corney ◽  
D. B. Whitehouse ◽  
D. A. Hopkinson ◽  
C. H. Rodeck ◽  
K. Nicolaides ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Blood Sampling ◽  
Fetal Blood ◽  
Fetal Blood Sampling ◽  
Antitrypsin Deficiency ◽  
Alpha 1 Antitrypsin Deficiency ◽  
Alpha 1 Antitrypsin

Prenatal diagnosis for hemoglobinopathies – 10 years experience using fetal blood sampling

Pathology ◽  
1993 ◽  
Vol 25 (1) ◽  
pp. 48-51 ◽  
Author(s):  
Vasili Berdoukas ◽  
Janet Argyle ◽  
Wendy Cox ◽  
Colin Fisher ◽  
Peter Warren
Keyword(s):  
Prenatal Diagnosis ◽  
Blood Sampling ◽  
Fetal Blood ◽  
Fetal Blood Sampling

Early fetal blood sampling — another available option for early prenatal diagnosis

1997 ◽  
Vol 25 (6) ◽  
pp. 505-508 ◽  
Author(s):  
Chinnaiya Anandakumar ◽  
Venkat Annapoorna ◽  
Yee Chee Wong ◽  
Dawn Chia ◽  
Bongso Ariff ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Blood Sampling ◽  
Fetal Blood ◽  
Fetal Blood Sampling

Prenatal Diagnosis of Haemophilia by Assay of Fetal Factors VIIIC and IX and Immunoradiometric Assay of Factor VIII Clotting Antigen (VIIICAg)

1979 ◽  
Author(s):  
R.S. Mibashan ◽  
C.H. Rodeck ◽  
J.K. Thumpston ◽  
I.R. Peake ◽  
A.L. Bloom
Keyword(s):  
Prenatal Diagnosis ◽  
Normal Serum ◽  
Blood Sampling ◽  
Added Value ◽  
Ultra Sound ◽  
Immunoradiometric Assay ◽  
Fetal Blood ◽  
Fetal Blood Sampling ◽  
Normal Ranges ◽  
Definition Of

Initial studies in adults measured foetor VIII clotting antigen (VIIICAg) in normal serum or plasma by on immunaradiometric assay (IRMA) and showed it grossly reduced or absent in 29 of 30 haemophilic kindreds. Pure fetal blood has been obtained (C.H.R.) at 15-22 weeks by direct fetoscopy with realtime ultra-sound in 64 (86%) of 74 patients studied diagnostically or pre-abortion. At 18-22 weeks 48 of 51 fetoscopies (94%) yielded pure fetal blood. In 22 consecutive somples of fetal citrate-plasma VIIIC was 32-79 ( 50) u/ dl, and FIX 8-18 ( 12) u/dl. VIIICAg in 9 fetoscopic plasmas ranged from 11-29 ( 20) u/ dl, and in 8 su ch sera VIIICAg was 4-14 ( 9) u/dl. VIIICAg levels in amniotic fluid were < 0.1 u/dl. Blood was obtained from 6 mole fetuses of obligate hoemophilia A carriers: In 3 only post-termination serum was available, and in one of these VIIICAg of <0.1 u/dl was found. In another both fetoscopic plasma and abortus serum hod < 0.1 u/dl VIIICAg. In the other 2, fetal blood-sampling gave plasma VIIIC levels of 49 and 63 u/dl, and VIIICAg of 13 and 16 u/dl; since these values were within their normal ranges, the pregnancies continued and their neonatal status is still awaited (Feb .79). The results suggest that prenatal diagnosis of haemophilia is possible by combining modified coagulant assays or IRMA with meticulous fetal blood sampling. Further definition of their normal ranges, relative predictive value and added value of VIIIRAg assay is needed.

Prenatal Diagnosis of Rubella Infection by Fetal Blood Sampling

2010 ◽  
Vol 17 (2) ◽  
pp. 113-117 ◽  
Author(s):  
Kaoru Suzumori ◽  
Tadashi Iida ◽  
Ritsuko Adachi ◽  
Setsuo Okada ◽  
Yoshiaki Yagami
Keyword(s):  
Prenatal Diagnosis ◽  
Blood Sampling ◽  
Fetal Blood ◽  
Rubella Infection ◽  
Fetal Blood Sampling
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