Correlation between prenatal ultrasound and fetal autopsy findings in fetal anomalies terminated in the second trimester

2007 ◽  
Vol 27 (5) ◽  
pp. 457-462 ◽  
Author(s):  
Hulya Akgun ◽  
Mustafa Basbug ◽  
Mahmut Tuncay Ozgun ◽  
Ozlem Canoz ◽  
Fatma Tokat ◽  
...  
Keyword(s):  
Prenatal Ultrasound ◽  
Second Trimester ◽  
Fetal Anomalies ◽  
Fetal Autopsy ◽  
Autopsy Findings

Correlation between prenatal ultrasound and fetal autopsy findings on urinary system anomalies terminated in the second trimester

2014 ◽  
Vol 34 (3) ◽  
pp. 285-290 ◽  
Author(s):  
Hulya Akgun ◽  
Mustafa Basbug ◽  
Mahmut Tuncay Ozgun ◽  
Figen Ozturk ◽  
Turhan Okten
Keyword(s):  
Prenatal Ultrasound ◽  
Urinary System ◽  
Second Trimester ◽  
Fetal Autopsy ◽  
Autopsy Findings

Correlation between prenatal ultrasound and autopsy findings: a study of second-trimester abortions

2006 ◽  
Vol 28 (7) ◽  
pp. 925-933 ◽  
Author(s):  
A. Kaasen ◽  
J. Tuveng ◽  
A. Heiberg ◽  
H. Scott ◽  
G. Haugen
Keyword(s):  
Prenatal Ultrasound ◽  
Second Trimester ◽  
Autopsy Findings

scholarly journals Second-trimester fetal autopsy: A morphological study with prenatal USG correlations and clinical implications

2018 ◽  
Vol 10 (03) ◽  
pp. 338-345
Author(s):  
Chaitra Venkataswamy ◽  
Umamaheswari Gurusamy ◽  
S. Vidhya Lakshmi
Keyword(s):  
Histopathological Examination ◽  
Recurrence Risk ◽  
Final Diagnosis ◽  
Prenatal Ultrasound ◽  
Intrauterine Fetal Death ◽  
Complete Agreement ◽  
Second Trimester ◽  
Fetal Autopsy ◽  
Increased Risk ◽  
Autopsy Examination

ABSTRACT OBJECTIVES: The objective of this study is to analyze the second-trimester fetal autopsies and to reemphasize the role of autopsy by comparing autopsy findings with prenatal ultrasound observations. MATERIALS AND METHODS: Retrospective analysis of second-trimester fetal autopsies over a period of 7.5 years (January 2009–June 2016). A standard protocol of autopsy procedure was followed, which included external examination with photography, X-ray, internal examination, and histopathological examination. In fetuses with congenital malformations (CMs), the findings of prenatal ultrasonogram and autopsy examination were compared. RESULTS: We analyzed a total of 66 fetuses, which includes 17 intrauterine fetal death, 49 terminations for CM, and increased risk for chromosomal abnormality. In fetuses with CM, multiple anomalies were more common than a single anomaly. The most common anomalies were seen involving central nervous system (neural tube defect) followed by the genitourinary system. Autopsy confirmed prenatal ultrasound findings in all cases except three. Complete agreement between USG findings and autopsy were seen in 17 cases (39.7%). Additional findings on autopsy were noted in 25 cases (62.2%). Among these, 15 cases had a significant change of recurrence risk due to altered initial ultrasound diagnosis. CONCLUSION: Fetal autopsy plays an important role in arriving at the final diagnosis and detecting the cause of death. This information is very essential for the clinicians, in genetic counseling of the parents, and management of future pregnancies.

Correlation of Prenatal Ultrasound Diagnosis and Pathologic Findings in Fetal Anomalies

1999 ◽  
Vol 2 (2) ◽  
pp. 131-142 ◽  
Author(s):  
Chen-Chih J. Sun ◽  
Kathryn Grumbach ◽  
Donna T. DeCosta ◽  
Carol M. Meyers ◽  
Jeffrey S. Dungan
Keyword(s):  
Prenatal Diagnosis ◽  
False Positive ◽  
Chromosomal Abnormalities ◽  
False Negative ◽  
Prenatal Ultrasound ◽  
Complete Agreement ◽  
Fetal Anomalies ◽  
Autopsy Findings ◽  
Organ Systems ◽  
The Us

This retrospective study compared the prenatal ultrasound (US) diagnosis with autopsy findings in 61 intact fetuses following induced abortion and 36 fragmented fetuses from dilatation and evacuation (D&E). In intact fetuses, complete agreement between US diagnosis and autopsy findings was achieved in 65.6% of cases in the central nervous system (CNS) and 47.5% in other somatic organ systems (SOS). There were major differences between US and autopsy findings involving the CNS in 6.5% of cases and SOS in 27.9%. Correlation was better for evaluation of renal anomalies (complete agreement in 63.6% of 11 suspected cases, 2 false-positive and no false-negative cases) than congenital heart disease (complete agreement in 27.3% of 11 suspected cases, 5 false-positive and 3 false-negative cases). In D&E specimens, a prenatal diagnosis of neural tube defect (NTD) was confirmed in 90% of cases. However, due to fragmentation of fetal parts, the US diagnosis in the CNS could not be confirmed totally (69.4%) or partially (2.8%) in fetuses with chromosomal abnormalities (ChA) or multiple congenital anomalies (MCA). Nonetheless, the US diagnosis of SOS was confirmed in six cases on D&E, including Meckel-Gruber syndrome, cystic hygroma, renal agenesis with contralateral renal dysplasia, cardiac defect, fetal hydrops, and tracheal atresia. Our results show that a thorough autopsy of an intact fetus after abortion is necessary to confirm prenatal diagnosis and allow proper management and counseling. The pathologic examination of D&E specimens can reliably confirm the US diagnosis of NTD, but it is very limited in identifying other fetal anomalies.

scholarly journals Impact of SARS-CoV-2 on Fetal Malformation During Pregnancy: A Case Report of Fetal Autopsy

2020 ◽  
Author(s):  
Yuping Guo ◽  
Jiacai Ren ◽  
Jingping Yuan ◽  
Di Lei ◽  
Nawsherwan . ◽  
...  
Keyword(s):  
Case Report ◽  
Congenital Defects ◽  
Fetal Malformation ◽  
Second Trimester ◽  
Fetal Anomalies ◽  
Fetal Autopsy ◽  
Case Presentation ◽  
Multiple Risk Factors ◽  
Second Trimester Pregnancy ◽  
The Impact

Abstract Background: Little is known about the impact of SARS-CoV-2 on fetal anomalies. Case presentation: We described a case report of fetal anomalies during second-trimester (25+3 weeks) pregnancy. The fetal autopsy was found with abnormal heart anatomy (including ventricular septal defect, oval hole valve missing, and pericardial effusion), polycystic kidney, and acute chorioamnionitis. Conclusions: SARS-CoV-2 infection in second-trimester pregnancy not the direct factor resulted in congenital defects, and multiple risk factors contribute to these changes.

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