Maternal serum free-β-chorionic gonadotrophin, pregnancy-associated plasma protein-A and fetal nuchal translucency thickness at 10–13+6 weeks in relation to co-variables in pregnant Saudi women

2007 ◽  
Vol 27 (4) ◽  
pp. 303-311 ◽  
Author(s):  
Mohammed-Salleh M. Ardawi ◽  
Hasan A. Nasrat ◽  
Abdulrahim A. Rouzi ◽  
Mohammed H. Qari ◽  
Mohammed H. Al-Qahtani ◽  
...  
Keyword(s):  
Plasma Protein ◽  
Protein A ◽  
Nuchal Translucency ◽  
Maternal Serum ◽  
Chorionic Gonadotrophin ◽  
Serum Free ◽  
Saudi Women

Maternal serum human chorionic gonadotrophin and pregnancy-associated plasma protein a, markers for fetal down syndrome at 8–14 weeks

1994 ◽  
Vol 14 (3) ◽  
pp. 203-208 ◽  
Author(s):  
M. C. M. Macintosh ◽  
R. Iles ◽  
B. Teisner ◽  
K. Sharma ◽  
T. Chard ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Plasma Protein ◽  
Protein A ◽  
Maternal Serum ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin

scholarly journals The Relationship Between First-Trimester Aneuploidy Markers and Birth Weight

2021 ◽  
pp. 1-6
Author(s):  
Cenk Soysal ◽  
İsmail Biyik ◽  
Özlem Erten ◽  
Onur Ince ◽  
Hatice Sari ◽  
...  
Keyword(s):  
Plasma Protein ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Protein A ◽  
First Trimester ◽  
Nuchal Translucency ◽  
Maternal Serum ◽  
Large For Gestational Age ◽  
Aneuploidy Screening ◽  
Beta Human Chorionic Gonadotropin

OBJECTIVE: We aimed to determine the relationship between the first-trimester aneuploidy screeningma and the predicted weight at birth: Small for gestational age and large for gestational age. STUDY DESIGN: 594 low-risk pregnant women with a singleton pregnancy, who underwent first-trimester aneuploidy screening by measuring nuchal translucency, maternal serum free beta-human chorionic gonadotropin, and pregnancy-associated plasma protein-A were included in the study. Those weighing above the 3rd percentile and below the 10th percentile were defined as small for gestational age, and those over the 90th percentile were defined as large for gestational age. RESULTS: A total of 594 pregnant women were enrolled. The mean maternal age of the studied group was 28.8±5.5 years. Low maternal serum pregnancy-associated plasma protein-A levels and decreased nuchal translucency measurements were associated with the small for gestational age newborn (p<0.001 and p=0.001, respectively). There is a significant correlation with large for gestational age for newborns only with an increase in maternal serum pregnancy-associated plasma protein-A levels (p=0.001). beta-human chorionic gonadotropin levels were not associated with the birth weight (p=0.735). CONCLUSION: Maternal serum pregnancy-associated plasma protein-A levels, one of the markers in first-trimester aneuploidy screening, can be used in the prediction of small for gestational age and large for gestational age However, due to its low correlation, it is not a suitable screening test for clinical practice.

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