Fetal abnormalities leading to termination of singleton pregnancy: the 7-year experience of a single medical center

2006 ◽  
Vol 26 (10) ◽  
pp. 938-943 ◽  
Author(s):  
Zvi Vaknin ◽  
Ido Ben-Ami ◽  
Orit Reish ◽  
Arie Herman ◽  
Ron Maymon
Keyword(s):  
Medical Center ◽  
Singleton Pregnancy ◽  
Fetal Abnormalities

scholarly journals Clinical and ultrasound features associated with congenital cytomegalovirus infection as potential predictors for targeted newborn screening in high-risk pregnancies

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Hitomi Imafuku ◽  
Hideto Yamada ◽  
Akiko Uchida ◽  
Masashi Deguchi ◽  
Tokuro Shirakawa ◽  
...  
Keyword(s):  
Preterm Delivery ◽  
Medical Center ◽  
Clinical Manifestations ◽  
High Sensitivity ◽  
Clinical Findings ◽  
Youden Index ◽  
Cmv Infection ◽  
Fetal Abnormality ◽  
Congenital Cytomegalovirus ◽  
Fetal Abnormalities

AbstractThis prospective cohort study aimed to determine clinical factors associated with congenital cytomegalovirus (CMV) infection in pregnancy. Newborns born at a perinatal medical center received PCR analyses for CMV-DNA in their urine with informed consent. Clinical data, including age, maternal fever or flu-like symptoms, complications, ultrasound fetal abnormality, gestational weeks at delivery, and birth weight, were collected. Logistic regression analyses determined clinical findings associated with congenital CMV infection (cCMV). cCMV was diagnosed in 32 of 4380 pregnancies. Univariate and multivariable analyses revealed that age < 25 years old (OR 2.7, 95% CI 1.1–6.6; p < 0.05), the presence of maternal fever or flu-like symptoms (5.4, 2.6–11.2; p < 0.01), ultrasound fetal abnormalities (12.7, 5.8–27.7; p < 0.01), and preterm delivery at less than 34 gestational weeks (2.6, 1.1–6.0; p < 0.05) were independent clinical findings associated with cCMV. A combination of maternal fever/flu-like symptoms, ultrasound fetal abnormalities, or preterm delivery at less than 34 gestational weeks as optimal predictive factors showed 90.6% sensitivity, 66.4% specificity, and a maximum Youden index of 0.57. CMV-DNA tests in the urine of newborns born to mothers with these clinical manifestations may be an effective method in detecting cCMV as a targeted screening with a high sensitivity.

scholarly journals The effect of pregnancy and the duration of postpartum convalescence on the physical fitness of healthy women: A cohort study of active duty servicewomen receiving 6 weeks versus 12 weeks convalescence

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0255248
Author(s):  
David W. DeGroot ◽  
Collin A. Sitler ◽  
Michael B. Lustik ◽  
Kelly L. Langan ◽  
Keith G. Hauret ◽  
...  
Keyword(s):  
Weight Gain ◽  
Physical Fitness ◽  
Medical Center ◽  
Active Duty ◽  
Failure Rates ◽  
Singleton Pregnancy ◽  
Physical Fitness Test ◽  
Modifiable Factors ◽  
Pregnancy And Postpartum ◽  
Associate Risk

Introduction Pregnancy profoundly affects cardiovascular and musculoskeletal performance requiring up to 12 months for recovery in healthy individuals. Objective To assess the effects of extending postpartum convalescence from 6 to 12 weeks on the physical fitness of Active Duty (AD) soldiers as measured by the Army Physical Fitness Test (APFT) and Body Mass Index (BMI). Methods We conducted a retrospective study of AD soldiers who delivered their singleton pregnancy of ≥ 32weeks gestation at a tertiary medical center. Pre- and post-pregnancy APFT results as well as demographic, pregnancy, and postpartum data were collected. Changes in APFT raw scores, body composition measures, and failure rates across the 6-week and 12-week convalescent cohorts were assessed. Multivariable regressions were utilized to associate risk factors with failure. Results Four hundred sixty women met inclusion criteria; N = 358 in the 6 week cohort and N = 102 in the 12 week cohort. Demographic variables were similar between the cohorts. APFT failure rates across pregnancy increased more than 3-fold in both groups, but no significant differences were found between groups in the decrement of performance or weight gain. With the combined cohort, multivariable regression analysis showed failure on the postpartum APFT to be independently associated with failure on the pre-pregnancy APFT (OR = 16.92, 95% CI 4.96–57.77), failure on pre-pregnancy BMI (OR = 8.44, 95% CI 2.23–31.92), elevated BMI at 6–8 weeks postpartum (OR = 4.02, 95% CI 1.42–11.35) and not breastfeeding at 2 months (OR = 3.23, 95% CI 1.48–7.02). Within 36 months of delivery date, 75% of women had achieved pre-pregnancy levels of fitness. Conclusion An additional 6 weeks of convalescence did not adversely affect physical performance or BMI measures in AD Army women following pregnancy. Modifiable factors such as pre- and post-pregnancy conditioning and weight, weight gain in pregnancy and always breastfeeding were found to be significant in recovery of physical fitness postpartum.

Fetal abnormalities leading to third trimester abortion: nine-year experience from a single medical center

2009 ◽  
Vol 29 (3) ◽  
pp. 223-228 ◽  
Author(s):  
Oshri Barel ◽  
Zvi Vaknin ◽  
Noam Smorgick ◽  
Orit Reish ◽  
Sonia Mendlovic ◽  
...  
Keyword(s):  
Medical Center ◽  
Third Trimester ◽  
Trimester Abortion ◽  
Fetal Abnormalities

scholarly journals Children born with assisted technology: a focus on parents’ reproductive health

2021 ◽  
pp. 539-543
Author(s):  
Daria A. Kinsht ◽  
◽  
Mariia K. Soboleva ◽  
Keyword(s):  
Reproductive Health ◽  
Assisted Reproductive Technologies ◽  
Medical Center ◽  
Newborn Infants ◽  
Uterine Cavity ◽  
Perinatal Outcomes ◽  
Reproductive Technologies ◽  
Singleton Pregnancy ◽  
Vitro Fertilization

Aim. To assess the main indicators of the initial reproductive health of parents, somatic health of the mother and their impact on the health of children born with singleton pregnancy ART. Materials and methods. The study included all newborn infants from singleton ART who were born at the Avicenna Medical Center (Novosibirsk) over the period 2006–2017 (n=409) and their parents (n=818). All stages of overcoming infertility (from the moment the parents go to the clinic to the birth of children) are considered in the context of one center, in a relatively homogeneous social group, with ensuring continuity at all stages. The average experience of infertility in couples was 7.2±0.2 years. The groups were formed depending on the type of infertility and the method of assisted reproductive technologies (ART) used: 205 children were born using in vitro fertilization (IVF), 204 children were born using the method of Intracytoplasm Sperm Injection (ICSI). The method of IVF and transfer of embryos into the uterine cavity is more often used in women with tuboperitoneal, endocrine types of infertility (premature ovarian failure syndrome), as well as in infertility associated with endometriosis. More serious reproductive problems (severe forms of male infertility, a combination of several types of infertility) in most cases lead to the use of more serious technological methods of ART, in particular, the addition of IVF and embryo transfer by the ICSI method. The reasons underlying infertility in most cases lead not only to the choice of the ART method, but also determine the characteristics of the course of pregnancy and the development of the intrauterine fetus. Pregnancy in the IVF group is significantly more often complicated by the threat of termination and premature birth, while ICSI pregnancy more often leads to impaired development of the intrauterine fetus. Conclusion. Features of medical support of women during the preparation for ART and, of course, during pregnancy, with a comprehensive, interdisciplinary correction of expected complications in each of the groups, will improve the perinatal outcomes of induced pregnancy and will contribute to the birth of healthy offspring.

scholarly journals Single Umbilical Artery and Pregnancy Outcome: Cause for Concern

2012 ◽  
Vol 4 (2) ◽  
pp. 103-105 ◽  
Author(s):  
Pushpalatha LNU ◽  
Gonnabaktula Naga Vasanthalakshmi ◽  
Priyanka Mehta ◽  
S Asha Devi
Keyword(s):  
Pregnancy Outcome ◽  
Umbilical Artery ◽  
Medical Center ◽  
Singleton Pregnancy ◽  
Single Umbilical Artery ◽  
Renal Anomalies ◽  
Cardiac Anomalies ◽  
Doppler Study ◽  
A Prospective Study ◽  
Singleton Pregnancies

ABSTRACT Objective To study the pregnancy outcome of antenatal women diagnosed with single umbilical artery (SUA) in singleton pregnancy in tertiary medical center and its association with intrauterine growth restriction (IUGR), renal and cardiac anomalies. Materials and methods We performed a prospective study of 6,711 singleton pregnancies at Sri Ramachandra Medical College, Chennai, between July 2009 and June 2011 and the pregnancies diagnosed with SUA were followed. The primary outcomes were renal anomalies, cardiac anomalies and IUGR. Results Of the 6,711 pregnancies there were 59 (0.88%) cases of SUA diagnosed at anatomic survey. Thirty seven pregnancies had isolated SUA (62.7%) and 22 singleton pregnancies had associated malformations (37.2%). Conclusion Our data suggests that the prevalence of SUA and associated anomalies seems to be similar to that reported in other countries. Evaluating cord vessels is important and fetuses with isolated SUA need more detailed assessment and monitoring1 including Doppler study in the presence of IUGR. SUA with multiple anomalies need further evalution with fetal echocardiogram and invasive tests like amniocentesis for karyotyping. How to cite this article Vasanthalakshmi GN, Pushpalatha, Mehta P, Devi SA. Single Umbilical Artery and Pregnancy Outcome: Cause for Concern. J South Asian Feder Obst Gynae 2012;4(2):103-105.

scholarly journals OP15.08: Fetal abnormalities leading to 3rdtrimester abortion: 9 year experience from a single Medical Center

2008 ◽  
Vol 32 (3) ◽  
pp. 362-362
Author(s):  
O. Barel ◽  
Z. Vaknin ◽  
N. Smorgick ◽  
O. Reish ◽  
S. Mendelovic ◽  
...  
Keyword(s):  
Medical Center ◽  
Fetal Abnormalities

Fetal abnormalities leading to termination of twin pregnancies: the 17-year experience of a single medical center

2016 ◽  
Vol 30 (3) ◽  
pp. 347-351 ◽  
Author(s):  
Yaakov Melcer ◽  
Ran Svirsky ◽  
Zvi Vaknin ◽  
Orna Levinsohn-Tavor ◽  
Noa Feldman ◽  
...  
Keyword(s):  
Medical Center ◽  
Fetal Abnormalities ◽  
Twin Pregnancies

Termination of pregnancy due to fetal abnormalities performed after 32 weeks’ gestation: survey of 57 fetuses from a single medical center

2017 ◽  
Vol 31 (6) ◽  
pp. 740-746 ◽  
Author(s):  
Noa Feldman ◽  
Yaakov Melcer ◽  
Edward Hod ◽  
Orna Levinsohn-Tavor ◽  
Ran Svirsky ◽  
...  
Keyword(s):  
Medical Center ◽  
Termination Of Pregnancy ◽  
Fetal Abnormalities

Termination of Pregnancy due to Fetal Abnormalities Performed after 23 Weeks’ Gestation: Analysis of Indications in 144 Cases from a Single Medical Center

2009 ◽  
Vol 25 (2) ◽  
pp. 291-296 ◽  
Author(s):  
Zvi Vaknin ◽  
Yael Lahat ◽  
Oshri Barel ◽  
Ido Ben-Ami ◽  
Orit Reish ◽  
...  
Keyword(s):  
Medical Center ◽  
Termination Of Pregnancy ◽  
Fetal Abnormalities

Medicaid & Medicare: D.C. Appellate Court Denies Claim for Medicare Reimbursement of GME Cost

1999 ◽  
Vol 27 (2) ◽  
pp. 205-205
Author(s):  
choeffel Amy
Keyword(s):  
Medical Center ◽  
Federal District ◽  
Federal Court ◽  
University Of Pennsylvania ◽  
District Court ◽  
Appellate Court ◽  
Court Of Appeals ◽  
Department Of Health ◽  
Administrative Proceedings ◽  
Summary Judgment

The U.S. Court of Appeals for the District of Columbia upheld, in Presbyterian Medical Center of the University of Pennsylvania Health System v. Shalala, 170 F.3d 1146 (D.C. Cir. 1999), a federal district court ruling granting summary judgment to the Department of Health and Human Services (DHHS) in a case in which Presbyterian Medical Center (PMC) challenged Medicare's requirement of contemporaneous documentation of $828,000 in graduate medical education (GME) expenses prior to increasing reimbursement amounts. DHHS Secretary Donna Shalala denied PMC's request for reimbursement for increased GME costs. The appellants then brought suit in federal court challenging the legality of an interpretative rule that requires requested increases in reimbursement to be supported by contemporaneous documentation. PMC also alleged that an error was made in the administrative proceedings to prejudice its claims because Aetna, the hospital's fiscal intermediary, failed to provide the hospital with a written report explaining why it was denied the GME reimbursement.

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