From sample preparation to NMR‐based metabolic profiling in food commodities: The case of table olives

2021 ◽  
Author(s):  
Stavros Beteinakis ◽  
Anastasia Papachristodoulou ◽  
Emmanuel Mikros ◽  
Maria Halabalaki
Keyword(s):  
Sample Preparation ◽  
Metabolic Profiling ◽  
Table Olives ◽  
Food Commodities

An overview of fecal sample preparation for global metabolic profiling

2015 ◽  
Vol 113 ◽  
pp. 137-150 ◽  
Author(s):  
Olga Deda ◽  
Helen G. Gika ◽  
Ian D. Wilson ◽  
Georgios A. Theodoridis
Keyword(s):  
Sample Preparation ◽  
Fecal Sample ◽  
Metabolic Profiling

Evaluation and optimization of sample preparation methods for metabolic profiling analysis ofEscherichia coli

2015 ◽  
Vol 36 (18) ◽  
pp. 2140-2147 ◽  
Author(s):  
Xiyue Wang ◽  
Fengxu Yang ◽  
Yuansheng Zhang ◽  
Guowang Xu ◽  
Yang Liu ◽  
...  
Keyword(s):  
Sample Preparation ◽  
Metabolic Profiling ◽  
Ofescherichia Coli ◽  
Preparation Methods ◽  
Metabolic Profiling Analysis ◽  
Profiling Analysis ◽  
Sample Preparation Methods

Sample preparation optimization in fecal metabolic profiling

2017 ◽  
Vol 1047 ◽  
pp. 115-123 ◽  
Author(s):  
Olga Deda ◽  
Anastasia Chrysovalantou Chatziioannou ◽  
Stella Fasoula ◽  
Dimitris Palachanis ◽  
Νicolaos Raikos ◽  
...  
Keyword(s):  
Sample Preparation ◽  
Metabolic Profiling

scholarly journals Screening blood spots for inborn errors of metabolism by electrospray tandem mass spectrometry with a microplate batch process and a computer algorithm for automated flagging of abnormal profiles

1997 ◽  
Vol 43 (7) ◽  
pp. 1129-1141 ◽  
Author(s):  
Mohamed S Rashed ◽  
Martin P Bucknall ◽  
Douglas Little ◽  
Amin Awad ◽  
Minnie Jacob ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Sample Preparation ◽  
Tandem Mass Spectrometry ◽  
Metabolic Profiling ◽  
Inborn Errors Of Metabolism ◽  
Batch Process ◽  
Tandem Mass ◽  
Electrospray Tandem Mass Spectrometry ◽  
Inborn Errors ◽  
Diagnostic Parameters

Abstract Metabolic profiling of amino acids and acylcarnitines from blood spots by automated electrospray tandem mass spectrometry (ESI-MS/MS) is a powerful diagnostic tool for inborn errors of metabolism. New approaches to sample preparation and data interpretation have helped establish the methodology as a robust, high-throughput neonatal screening method. We introduce an efficient 96-well-microplate batch process for blood-spot sample preparation, with which we can obtain high-quality profiles from 500-1000 samples per day per instrument. A computer-assisted metabolic profiling algorithm automatically flags abnormal profiles. We selected diagnostic parameters for the algorithm by comparing profiles from patients with known metabolic disorders and those from normal newborns. Reference range and cutoff values for the diagnostic parameters were established by measuring either metabolite concentrations or peak ratios of certain metabolite pairs. Rigorous testing of the algorithm demonstrates its outstanding clinical sensitivity in flagging abnormal profiles and its high cumulative specificity.

scholarly journals Sample Preparation for Metabolic Profiling using MALDI Mass Spectrometry Imaging

10.3791/62008 ◽  
2020 ◽  
Author(s):  
Kelly Veerasammy ◽  
Yuki X. Chen ◽  
Sami Sauma ◽  
Mathilde Pruvost ◽  
David K. Dansu ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Sample Preparation ◽  
Metabolic Profiling ◽  
Mass Spectrometry Imaging ◽  
Maldi Mass Spectrometry ◽  
Maldi Mass Spectrometry Imaging
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