Metabolomic analysis reveals the valuable bioactive compounds of Ardisia elliptica

2020 ◽  
Author(s):  
Pei Lou Wong ◽  
Nurul Shazini Ramli ◽  
Chin Ping Tan ◽  
Azrina Azlan ◽  
Faridah Abas
Keyword(s):  
Bioactive Compounds ◽  
Metabolomic Analysis ◽  
Ardisia Elliptica

scholarly journals LC-ESI/LTQOrbitrap/MS Metabolomic Analysis of Fennel Waste (Foeniculum vulgare Mill.) as a Byproduct Rich in Bioactive Compounds

Foods ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 1893
Author(s):  
Maria Assunta Crescenzi ◽  
Gilda D’Urso ◽  
Sonia Piacente ◽  
Paola Montoro
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Bioactive Metabolites ◽  
Flavonoid Glycosides ◽  
Metabolomic Analysis ◽  
Foeniculum Vulgare ◽  
Plant Parts ◽  
Accurate Mass Measurements ◽  
Metabolite Profiles ◽  
Hydroxycinnamic Acid Derivatives

Food industries produce a high amount of waste every year. These wastes represent a source of bioactive compounds to be used to produce cosmetic and nutraceutical products. In this study, the possibility to retrain food waste as a potential source of bioactive metabolites is evaluated. In particular, metabolite profiles of different parts (bulb, leaves, stems and little stems) of fennel waste were investigated by liquid chromatography coupled with mass spectrometry (LC-ESI/LTQ Orbitrap MS). To discriminate the different plant parts, a Multivariate Data Analysis approach was developed. Metabolomic analysis allowed the identification of different metabolites mainly belonging to hydroxycinnamic acid derivatives, flavonoid glycosides, flavonoid aglycons, phenolic acids, iridoid derivatives and lignans. The identification of compounds was based on retention times, accurate mass measurements, MS/MS data, exploration on specific metabolites database and comparison with data reported in the literature for F. vulgare. Moreover, the presence of different oxylipins was relieved; these metabolites for the first time were identified in fennel. Most of the metabolites identified in F. vulgare possess anti-inflammatory, antioxidant and/or immunomodulatory properties. Considering that polyphenols are described to possess antioxidant activity, spectrophotometric tests were performed to evaluate the antioxidant activity of each part of the fennel.

scholarly journals Metabolomic analysis of bioactive compounds in mature rhizomes and daughter rhizomes in ginger (Zingiber officinale)

2019 ◽  
Author(s):  
Zhexin Li ◽  
Ze-Xiong Chen ◽  
Jian-Min Tang ◽  
Yu-Song Jiang ◽  
Qin-Hong Liao ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Metabolic Pathways ◽  
Theoretical Basis ◽  
Chemical Constituents ◽  
Zingiber Officinale ◽  
Flavonoid Biosynthesis ◽  
Metabolomic Analysis ◽  
Comprehensive Development ◽  
Development And Utilization

Abstract Background The bioactive compounds of ginger (Zingiber officinale), such as gingerols, diarylheptanoids, and flavonoids, are of importance to human health because of their anticancer, antioxidant, and anti-inflammatory properties. The daughter rhizomes arise from mature rhizomes, but the pungency and pharmacological quality of the two rhizome types differ substantially. Results In this study, a metabolomic analysis was performed to investigate the biosynthesis of major bioactive compounds in the mature rhizome (R) and daughter rhizome (DR) in ginger. A total of 1212 differentially accumulated metabolites with p < 0.05 and |fold change| ≥ 1 were identified, of which 399 metabolites were more highly accumulated in R samples than in DR samples, whereas 211 metabolites were most highly accumulated in DR samples. Metabolic pathways associated with the bioactive compounds that determine the pharmacological activity of ginger, including the “terpenoid backbone biosynthesis”, “stilbenoid, diarylheptanoid, and gingerol biosynthesis”, and "flavonoid biosynthesis" pathways, were enriched in R samples, which indicated that bioactive compounds mainly accumulated in mature rhizomes of ginger. Conclusion Differences in the key bioactive chemical constituents between the rhizome and daughter rhizome were analyzed. These results provide a theoretical basis for comprehensive development and utilization of ginger resources.

Investigation of bioactive compounds in the genus Garcinia (Guttiferae) of Cameroon

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
B Biloa Messi ◽  
R Ho ◽  
A Meli Lannang ◽  
JG Tangmouo ◽  
A Marston ◽  
...  
Keyword(s):  
Bioactive Compounds

Strategies and Methods for a Sustainable Search for Bioactive Compounds

Planta Medica ◽  
2012 ◽  
Vol 78 (05) ◽  
Author(s):  
L Bohlin ◽  
C Alsmark ◽  
U Göransson ◽  
M Klum ◽  
C Wedén ◽  
...  
Keyword(s):  
Bioactive Compounds

Genome mining and characterisation of multiple bioactive compounds from a Burkholderia gladioli isolate collection

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
C Jones ◽  
MJ Bull ◽  
M Jenner ◽  
L Song ◽  
Y Dashti ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Genome Mining ◽  
Burkholderia Gladioli

Discovery of Novel Bioactive Compounds from Rhamnaceae Plants: The Initial Steps

2017 ◽  
Author(s):  
B Kang Kyo ◽  
J Park ◽  
H Hahn ◽  
W Han Byung ◽  
W Lee ◽  
...  
Keyword(s):  
Bioactive Compounds
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